Liquid chromatographic direct resolution of flecainide and its analogs on a chiral stationary phase based on (+)-(18-Crown-6)-2,3,11,12-tetracarboxylic acid

Chirality

Volumn 22, Issue 7, 2010, Pages 693-698

  Lee, Areum ^a   Choi, Hee Jung ^a   Hyun, Myung Ho ^a  

^a Pusan National University   (South Korea)

Author keywords

(+) 18 crown 6 2,3,11,12 tetracarboxylic acid; Chiral resolution; Chiral stationary phase; Enantiomer separation; Flecainide; Liquid chromatography

Indexed keywords

(18 CROWN 6) 2,3,11,12 TETRACARBOXYLIC ACID; ANTIARRHYTHMIC AGENT; CARBOXYLIC ACID DERIVATIVE; FLECAINIDE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; CHIRALITY; ENANTIOMER; HEART ARRHYTHMIA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY;

ANTI-ARRHYTHMIA AGENTS; BENZOATES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CROWN ETHERS; FLECAINIDE; STEREOISOMERISM;

EID: 77952772991     PISSN: 08990042     EISSN: 1520636X     Source Type: Journal    
DOI: 10.1002/chir.20818     Document Type: Article

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