Regioselective reaction of Ethyl 5-Acetyl-3,4-dihydropyridine-1(2 H)-carboxylate with hydrazines: A facile approach to new pyrazole derivatives

Synthesis

Volumn , Issue 11, 2010, Pages 1781-1786

  Maximov, Nazar B ^a,b   Mykhailiuk, Pavel K ^a,b   Golovach, Sergey M ^a   Tverdokhlebov, Anton V ^a,b   Voitenko, Zoya V ^b   Tolmachev, Andrey A ^a,b  

^a ENAMINE LTD   (Ukraine)

^b TARAS SHEVCHENKO NATIONAL UNIVERSITY OF KYIV   (Ukraine)

Author keywords

Hydrazine; Pyrazole; Regioselectivity; Tetrahydropyridine

Indexed keywords

DIHYDROPYRIDINES; PYRAZOLE; PYRAZOLE DERIVATIVES; PYRAZOLES; REGIO-SELECTIVE; REGIOSELECTIVE REACTIONS;

CARBOXYLATION; HYDRAZINE; PYRIDINE;

REGIOSELECTIVITY;

1 (1,4,5,6 TETRAHYDROPYRIDIN 3 YL)ETHANONE; 2 [4 (3 AMINOPROPYL) 3 METHYL 1H PYRAZOL 1 YL]ETHANOL; 3 (1 ISOBUTYL 3 METHYL 1H PYRAZOL 4 YL)PROPYLAMINE; 3 (1,3 DIMETHYL 1H PYRAZOL 4 YL)PROPYLAMINE; 3 [1 (1H BENZIMIDAZOL 2 YL) 3 METHYL 1H PYRAZOL 4 YL]PROPYLAMINE; 3 [1 (2 FLUOROPHENYL) 3 METHYL 1H PYRAZOL 4 YL]PROPYLAMINE; 3 [1 (3 CHLOROPHENYL) 3 METHYL 1H PYRAZOL 4 YL]PROPYLAMINE; 3 [1 (4 CHLOROPHENYL) 3 METHYL 1H PYRAZOL 4 YL]PROPYLAMINE; 3 [3 METHYL 1 (PYRIDIN 2 YLMETHYL) 1H PYRAZOL 4 YL]PROPYLAMINE; ETHYL (1,3 DIMETHYL 1H PYRAZOL 4 YL)PROPYLCARBAMATE; ETHYL 3 (1 ISOBUTYL 3 METHYL 1H PYRAZOLE 4 YL)PROPYLCARBAMATE; ETHYL 3 (3 METHYL 1 PHENYL 1H PYRAZOLE 4 YL)PROPYLCARBAMATE; ETHYL 3 [1 (1H BENZIMIDAZOL 2 YL) 3 METHYL 1H PYRAZOL 4 YL]PROPYLCARBAMATE; ETHYL 3 [1 (2 FLUOROPHENYL) 3 METHYL 1H PYRAZOL 4 YL]PROPYLCARBAMATE; ETHYL 3 [1 (2 HYDROXYETHYL) 3 METHYL 1H PYRAZOL 4 YL]PROPYLCARBAMATE; ETHYL 3 [1 (3 CHLOROPHENYL) 3 METHYL 1H PYRAZOL 4 YL]PROPYLCARBAMATE; ETHYL 3 [1 (4 CHLOROPHENYL) 3 METHYL 1H PYRAZOL 4 YL]PROPYLCARBAMATE; ETHYL 3 [3 METHYL 1 (PYRIDIN 2 YLMETHYL) 1H PYRAZOL4 YL]PROPYLCARBAMATE; ETHYL 5 ACETYL 3,4 DIHYDROPYRIDINE 1(2H) CARBOXYLATE; PYRAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; SYNTHESIS;

EID: 77952762270     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0029-1219760     Document Type: Article

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