Efficient encapsulation of plasmid DNA in pH-sensitive PMPC-PDPA polymersomes: Study of the effect of PDPA block length on copolymer-DNA binding affinity

Macromolecular Bioscience

Volumn 10, Issue 5, 2010, Pages 513-530

  Lomas, Hannah ^a   Du, Jianzhong ^a,b   Canton, Irene ^a   Madsen, Jeppe ^a   Warren, Nicholas ^a   Armes, Steven P ^a   Lewis, Andrew L ^c   Battaglia, Giuseppe ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b TONGJI UNIVERSITY   (China)

^c BIOCOMPATIBLES UK LTD   (United Kingdom)

Author keywords

Diblock copolymers; Encapsulation; pH sensitive; Plasmid DNA; Vesicles

Indexed keywords

2-METHACRYLOYLOXYETHYL PHOSPHORYLCHOLINE; AMPHIPHILIC DIBLOCK COPOLYMERS; BINDING AFFINITIES; BLOCK LENGTHS; DIBLOCK COPOLYMER; DIBLOCK COPOLYMERS; DNA BINDING AFFINITY; ELECTROSTATIC INTERACTIONS; ETHYL METHACRYLATES; HYDROPHILIC BLOCKS; PH SENSITIVE; PH VALUE; PH-SENSITIVITY; PHYSIOLOGICAL PH; PLASMID DNA; POLYMERSOMES; SALT CONCENTRATION; TERTIARY AMINE GROUPS;

BINDING ENERGY; BLOCK COPOLYMERS; COPOLYMERIZATION; DNA; ENCAPSULATION; GENES; MICROBIOLOGY; NUCLEIC ACIDS; PLASTIC PRODUCTS; POTENTIOMETRIC SENSORS;

PH EFFECTS;

AMPHOPHILE; COPOLYMER; NUCLEIC ACID; PLASMID DNA; POLY(2 METHACRYLOYLOXYETHYL PHOSPHORYLCHOLINE); POLY[2 (DIISOPROPYLAMINO)ETHYL METHACRYLATE]; SODIUM CHLORIDE; TERTIARY AMINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BIOCOMPATIBILITY; COLLOID; CONTROLLED STUDY; DISPERSION; DNA BINDING; DYNAMIC LIGHT SCATTERING; ENCAPSULATION; ENDOCYTOSIS; HYDROPHILICITY; LIGHT SCATTERING; NONHUMAN; PH; PKA; PROTON TRANSPORT; STATIC ELECTRICITY; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL;

ANIMALS; CAPSULES; DNA; HUMANS; HYDROGEN-ION CONCENTRATION; METHACRYLATES; NANOSTRUCTURES; PHOSPHORYLCHOLINE; PLASMIDS; POLYMETHACRYLIC ACIDS; STATIC ELECTRICITY; TRANSFECTION;

EID: 77952761390     PISSN: 16165187     EISSN: 16165195     Source Type: Journal    
DOI: 10.1002/mabi.201000083     Document Type: Article

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