Clinical trial: Five or ten cycles of granulocyte-monocyte apheresis show equivalent efficacy and safety in ulcerative colitis

Alimentary Pharmacology and Therapeutics

Volumn 31, Issue 12, 2010, Pages 1286-1295

  Dignass, A U ^a   Eriksson, A ^b   Kilander, A ^b   Pukitis, A ^c   Rhodes, J M ^d   Vavricka, S ^e  

^a AGAPLESION MARKUS KRANKENHAUS   (Germany)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^c PAULS STRADINS CLINICAL UNIVERSITY HOSPITAL   (Latvia)

^d ROYAL LIVERPOOL UNIVERSITY HOSPITAL   (United Kingdom)

^e UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

STEROID;

ADULT; APHERESIS; ARTICLE; CLINICAL EFFECTIVENESS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FATIGUE; FEMALE; GRANULOCYTE MONOCYTE ADSORPTIVE APHERESIS; HEADACHE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NAUSEA; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REMISSION; RHINOPHARYNGITIS; TREATMENT RESPONSE; ULCERATIVE COLITIS;

ADULT; BLOOD COMPONENT REMOVAL; COLITIS, ULCERATIVE; FEMALE; GRANULOCYTES; HUMANS; MALE; MIDDLE AGED; MONOCYTES; PROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; STEROIDS; TREATMENT OUTCOME;

EID: 77952758032     PISSN: 02692813     EISSN: 13652036     Source Type: Journal    
DOI: 10.1111/j.1365-2036.2010.04295.x     Document Type: Article

References (25)

1. Stange EF, Travis SPL, Vermeire S, et al. European evidence-based consensus on the diagnosis and management of ulcerative colitis: definitions and diagnosis. J Crohn's Colitis 2008 2 : 1 23.
2. Stein RB, Hanaur SB. Comparative tolerability of treatments for inflammatory bowel disease. Drug Saf 2000 23 : 429 448.
3. Rutgeerts P, Sandborn WJ, Feagan BG, et al. Infliximab for induction and maintenance therapy for ulcerative colitis. N Engl J Med 2005 353 : 2462 2476. (Pubitemid 41770166)
4. Baumgart DC. The diagnosis and treatment of Crohn's disease and ulcerative colitis. Dtsch Ärtzebl 2009 106 : 123 133.
5. Torres MI, Rios A. Current view of the immunopathogenesis in inflammatory bowel disease and its implications for therapy. World J Gastroenterol 2008 14 : 1972 1980.
6. Shimoyama T, Sawada K, Hiwatashi N, et al. Safety and efficacy of granulocyte and monocyte adsorption apheresis in patients with active ulcerative colitis: a multicenter study. J Clin Apher 2001 16 : 1 9.
7. Suzuki Y, Yoshimura N, Saniabadi AR, et al. Selective granulocyte and monocyte adsorptive apheresis as a first line treatment for steroid naïve patients with active ulcerative colitis. Dig Dis Sci 2004 49 : 565 571.
8. Kashiwagi N, Sugimura K, Koiwai H, et al. Immunomodulatory effects of granulocyte and monocyte adsorption apheresis as a treatment for patients with ulcerative colitis. Dig Dis Sci 2002 47 : 1334 1341.
9. Bicks RO, Groshart KD. Tempest about T-lymphocyte apheresis in Crohn's disease. Gastroenterology 1995 108 : 952 953.
10. Bicks RO, Groshart KD. The current status of T-lymphocyte apheresis (TLA) treatment of Crohn's disease. J Clin Gastroenterol 1989 11 : 136 138.
11. Kruis W, Dignass A, Steinhagen-Thiessen E, et al. Open label trial of granulocyte apheresis suggests therapeutic efficacy in chronically active steroid refractory ulcerative colitis. World J Gastroenterol 2005 11 : 7001 7006.
12. Japan Immunoresearch Laboratories Co., Ltd. Adacolumn, a Granulocyte and Monocyte/Macrophage Adsorption Apheresis Device. Prescribing information 2004; Authorized Representative, Otsuka Pharmaceutical Europe Ltd
13. Abreu MT, Plevy S, Sands BE, et al. Selective leukocyte apheresis for the treatment of inflammatory bowel disease. J Clin Gastroenterol 2007 41 : 874 888. (Pubitemid 350307073)
14. Hanai H. Positions of selective leukocytapheresis in the medical therapy of ulcerative colitis. World J Gastroenterol 2006 12 : 7568 7577.
15. Tanaka T, Okanobu H, Yoshimi S, et al. In patients with ulcerative colitis, adsorptive depletion of granulocytes and monocytes impacts mucosal level of neutrophils and clinically is most effective in steroid naive patients. Dig Liver Dis 2008 40 : 731 736.
16. Rachmilewitz D. Coated mesalazine (5-aminosalicylic acid) versus sulphasalazine in the treatment of active ulcerative colitis: a randomised trial. BMJ 1989 298 : 82 6.
17. Bresci G, Parisi G, Mazzoni G, et al. Granulocytaphresis versus methylprednisolone in patients with acute ulcerative colitis: 12 month follow up. J Gastroenterol Hepatol 2008 23 : 1678 1682.
18. Shimoyama T, Sawada K, Hiwatashi N, et al. Granulocytes and monocyte apheresis with the G-1 column in the treatment of patients with active ulcerative colitis. Jpn J Apher 1999 18 : 117 131.
19. Hanai H, Watanabe F, Takeuchi Y, et al. Leukocyte adsorptive apheresis for the treatment of ulcerative colitis: a prospective, uncontrolled, pilot study. Clin Gastroenterol Hepatol 2003 1 : 28 35.
20. Hanai H, Iida T, Takeuchi K, et al. Intensive granulocyte and monocyte adsorption versus intravenous prednisolone in patients with severe ulcerative colitis: an unblinded randomised multi-centre controlled study. Dig Liver Dis 2008 40 : 433 440.
21. Sands BE, Sandborn WJ, Feagan B, et al. A randomized, double-blind, sham-controlled study of granulocyte/monocyte apheresis for active ulcerative colitis. Gastroenterology 2008 135 : 400 409.
22. Habermalz B, Sauerland S. Clinical effectiveness of selective granulocyte, monocyte adsorptive apheresis with the Adacolumn® device in ulcerative colitis. Dig Dis Sci 2009 [Epub ahead of print].
23. Ruuska T, Wewer V, Lindgren F, et al. Granulocyte-monocyte adsorptive apheresis in pediatric inflammatory bower disease: results, practical issues, safety, and future perspectives. Inflamm Bowel Dis 2009 15 : 1049 1054.
24. Panes J, Guilera M, Ginard D, et al. Treatment cost of ulcerative colitis is apheresis with Adacolumn cost-effective? Dig Liver Dis 2007 39 : 617 625.
25. Hibi T, Sameshima Y, Sekiguchi Y, et al. Treating ulcerative colitis by Adacolumn therapeutic leucocytapheresis: clinical efficacy and safety based on surveillance of 656 patients in 53 centres in Japan. Dig Liver Dis 2009 41 : 570 577.