Heat stress deteriorates mitochondrial β-oxidation of long-chain fatty acids in cultured fibroblasts with fatty acid β-oxidation disorders

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 878, Issue 20, 2010, Pages 1669-1672

  Li, Hong ^a,b   Fukuda, Seiji ^a   Hasegawa, Yuki ^a   Purevsuren, Jamiyan ^a   Kobayashi, Hironori ^a   Mushimoto, Yuichi ^a   Yamaguchi, Seiji ^a  

^a SHIMANE UNIVERSITY FACULTY OF MEDICINE   (Japan)

^b NINGXIA MEDICAL UNIVERSITY   (China)

Author keywords

Acylcarnitine profiling; Fatty acids oxidation disorder; Heat stress; Tandem mass spectrometry

Indexed keywords

ACYL-COA; ACYLCARNITINE PROFILING; CARNITINE; HEALTHY CONTROLS; HEAT STRESS; IN-CELL; LONG-CHAIN ACYL-COA; LONG-CHAIN FATTY ACIDS; MEDIUM-CHAIN ACYL-COA DEHYDROGENASE; PALMITIC ACID; SUDDEN DEATHS; TANDEM MASS SPECTROMETRY;

ACIDS; CELL CULTURE; DEFECTS; FIBROBLASTS; MASS SPECTROMETRY; OXIDATION; THERMAL STRESS;

FATTY ACIDS;

ACYLCARNITINE; CARNITINE PALMITOYLTRANSFERASE; CARNITINE PALMITOYLTRANSFERASE II; LONG CHAIN ACYL COENZYME A DEHYDROGENASE; LONG CHAIN FATTY ACID; PALMITIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME DEFICIENCY; FATTY ACID OXIDATION; FEVER; FIBROBLAST; HEAT STRESS; HUMAN; HUMAN CELL; MASS SPECTROMETRY; MITOCHONDRION; PRIORITY JOURNAL;

ADOLESCENT; CARNITINE; CHILD; FATTY ACIDS; FEMALE; FIBROBLASTS; HEAT STRESS DISORDERS; HUMANS; LIPID METABOLISM, INBORN ERRORS; MALE; MITOCHONDRIA; OXIDATION-REDUCTION; TANDEM MASS SPECTROMETRY;

EID: 77952746412     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2010.01.046     Document Type: Article

References (21)

1. Rinaldo P., Matern D., and Bennett M.J. Annu. Rev. Physiol. 64 (2002) 477
2. Wilcken B., Wiley V., Hammond J., and Carpenter K. N. Engl. J. Med. 348 (2003) 2304
3. Ghisla S. Eur. J. Biochem. 271 (2004) 459
4. Spiekerkoetter U., Lindner M., Santer R., Grotzke M., Baumgartner M.R., Boehles H., de Klerk H., Knerr I., Koch H.G., Plecko B., Roschinger W., Schwab K.O., Scheible D., Wijburg F.A., schocke J., Mayatapek E., and Wendel U. J. Inherit. Metab. Dis. 32 (2009) 488
5. Lundemose J.B., Kolvraa S., Gregersen N., Christensen E., and Gregersen M. J. Clin. Pathol: Mol. Pathol. 50 (1997) 212
6. Strauss A.W., Powell C.K., Hale D.E., Anderson M.M., Ahuja A., Brackett J.C., and Sims H.F. Proc. Natl. Acad. Sci. U.S.A. 92 (1995) 10496
7. Ahmed R.G. Int. J. Dev. Neurosci. 23 (2005) 549
8. Togashi T., Matsuzono Y., Narita M., and Morishima T. Virus Res. 103 (2004) 75
9. Chen Y., Mizuguchi H., Yao D., Ide M., Kuroda Y., Shigematsu Y., Yamaguchi S., Yamaguchi M., Kinoshita M., and Kido H. FEBS Lett. 579 (2005) 2040
10. Purevsuren J., Hasegawa Y., Kobayashi H., Endo M., and Yamaguchi S. Brain Dev. 30 (2008) 520
11. Roe D.S., Yang B.Z., Vianey-Saban C., Struys E., Sweetman L., and Roe C.R. Mol. Genet. Metab. 87 (2006) 40
12. Roe D.S., Vianey-Saban C., Sharma S., Zabot M.T., and Roe C.R. Clin. Chim. Acta 312 (2001) 55
13. Olsen R.K.J., Olpin S.E., Andresen B.S., Miedzybrodzka Z.H., Pourfarzam M., Merinero B., Frerman F.E., Beresford M.W., Dean J.C.S., Cornelius N., Andersen O., Oldfors A., Holme E., Gregersen N., Douglass M., Turnbull D.M., and Morris A.A.M. Brain 130 (2007) 2045
14. Okun J.G., Kolker S., Schulze A., Kohlmuller D., Olgemoller K., and Lindner M. Biochim. Et. Biophys. Acta 1584 (2002) 91
15. Sim K.G., Hammond J., and Wilcken B. Clin. Chim. Acta 323 (2002) 37
16. Nada M.A., Rhead W.J., Sprecher H., Schulz H., and Roe C.R. J. Biol. Chem. 270 (1995) 530
17. schulze A., Lindner M., Kohlmuller D., Olgemoller K., Mayatepek E., and Hoffmann G.F. Pediatrics 111 (2003) 1399
18. Nomachi S., Nakajima T., Sakurada M., Ota N., Fukushi M., Yano K., and Jensen U.G. Ann. Rep. Sapporo City Inst. Public Health 34 (2007) 37
19. H. Li, S. Fukuda, Y. Hasegawa, H. Kobayashi, Y. Mushimoto, S. Yamaguchi, Brain Dev., 2009. [Epub ahead of print].
20. Garg U., and Dasouki M. Clin. Biochem. 39 (2006) 315
21. Yao D., Mizuguchi H., Yamaguchi M., Yamada H., Chida J., Shikata K., and Kido H. Hum. Mutat. 29 (2008) 718