D225G mutation in the hemagglutinin protein found in 3 severe cases of 2009 pandemic influenza A (H1N1) in Spain

Diagnostic Microbiology and Infectious Disease

Volumn 67, Issue 2, 2010, Pages 207-208

  Antón, Andrés ^a   Marcos, María Ángeles ^a   Martínez, Miguel Julián ^a   Ramón, Susana ^a   Martínez, Anna ^b   Cardeñosa, Neus ^b   Godoy, Pere ^b   Torner, Nuria ^b   De Molina, Patricia ^a   Isanta, Ricard ^a   Jiménez de Anta, María Teresa ^a   Pumarola, Tomàs ^a  

^a HOSPITAL CLÍNIC   (Spain)

^b Generalitat de Catalunya ^*  (Spain)

Author keywords

D225G mutation; Influenza; Pandemic

Indexed keywords

HEMAGGLUTININ;

ARTICLE; GENE MUTATION; GENE SEQUENCE; GENETIC LINKAGE; GEOGRAPHIC DISTRIBUTION; INFLUENZA VIRUS A H1N1; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; SPAIN; VIRUS ISOLATION; VIRUS TRANSMISSION;

HEMAGGLUTININS, VIRAL; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; MUTATION, MISSENSE; POINT MUTATION; SEQUENCE ANALYSIS, DNA; SPAIN;

EID: 77952746076     PISSN: 07328893     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diagmicrobio.2010.02.002     Document Type: Article

References (5)

1. Gagneux P., Cheriyan M., Hurtado-Ziola N., van der Linden E.C., Anderson D., McClure H., Varki A., Varki N.M. Human-specific regulation of alpha 2-6-linked sialic acids. J. Biol. Chem. 2003, 278:48245-48250.
2. Reina J. Factors affecting the virulence and pathogenicity of avian and human viral strains (influenza virus type A). Enferm. Infecc. Microbiol. Clin. 2002, 20:346-353.
3. Shinya K., Ebina M., Yamada S., Ono M., Kasai N., Kawaoka Y. Avian flu: influenza virus receptors in the human airway. Nature 2006, 440:435-436.
4. Tumpey T.M., Maines T.R., Van Hoeven N., Glaser L., Solórzano A., Pappas C., Cox N.J., Swayne D.E., Palese P., Katz J.M., García-Sastre A. A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission. Science 2007, 315:655-659.
5. van Riel D., Munster V.J., de Wit E., Rimmelzwaan G.F., Fouchier R.A., Osterhaus A.D., Kuiken T. Human and avian influenza viruses target different cells in the lower respiratory tract of humans and other mammals. Am J Pathol 2007, 171:1215-1223.