The clock genes period 1 and period 2 mediate diurnal rhythms in dioxin-induced Cyp1A1 expression in the mouse mammary gland and liver

Toxicology Letters

Volumn 196, Issue 1, 2010, Pages 28-32

  Qu, Xiaoyu ^a   Metz, Richard P ^b   Porter, Weston W ^b   Neuendorff, Nichole ^c   Earnest, Barbara J ^a   Earnest, David J ^a,c  

^a TEXAS A AND M UNIVERSITY   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

^c TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

AhR nuclear translocator; Aryl hydrocarbon receptor; Circadian clock; Cytochrome p450 enzymes; PAS genes; Xenobiotics

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; CLOCK GENE PERIOD 1; CLOCK GENE PERIOD 2; CYTOCHROME P450 1A1; TRANSCRIPTION FACTOR CLOCK; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CIRCADIAN RHYTHM; CONTROLLED STUDY; ENZYME INDUCTION; FEMALE; GENE EXPRESSION; GENE FUNCTION; LIVER; MAMMARY GLAND; MOUSE; MUTANT; NIGHT; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WILD TYPE;

ANIMALS; CIRCADIAN RHYTHM; CLOCK PROTEINS; CYTOCHROME P-450 CYP1A1; DIOXINS; FEMALE; LIVER; MAMMARY GLANDS, ANIMAL; MICE; MUTATION; PERIOD CIRCADIAN PROTEINS;

ANIMALIA; MAMMALIA; MUS;

EID: 77952744732     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2010.03.020     Document Type: Article

References (31)

1. Akhtar R.A., Reddy A.B., Maywood E.S., Clayton J.D., King V.M., Smith A.G., Gant T.W., Hastings M.H., Kyriacou C.P. Circadian cycling of the mouse liver transcriptome, as revealed by cDNA microarray, is driven by the suprachiasmatic nucleus. Curr. Biol. 2002, 12:540-550.
2. Bae K., Jin X., Maywood E.S., Hastings M.H., Reppert S.M., Weaver D.R. Differential functions of mPer1, mPer2, and mPer3 in the SCN circadian clock. Neuron 2001, 30:525-536.
3. Christou M., Savas U., Schroeder S., Shen X., Thompson T., Gould M.N., Jefcoate C.R. Cytochromes CYP1A1 and CYP1B1 in the rat mammary gland: cell-specific expression and regulation by polycyclic aromatic hydrocarbons and hormones. Mol. Cell. Endocrinol. 1995, 115:41-50.
4. Ciolino H.P., Yeh G.C. The steroid hormone dehydroepiandrosterone inhibits CYP1A1 expression in vitro by a post-transcriptional mechanism. J. Biol. Chem. 1999, 274:35186-35190.
5. Brd mice. J. Comp. Physiol. 2006, 192:769-775.
6. Duffield G.E. DNA microarray analyses of circadian timing: the genomic basis of biological time. J. Neuroendocrinol. 2003, 15:991-1002.
7. Fu L., Pelicano H., Liu J., Huang P., Lee C. The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo. Cell 2002, 111:41-50.
8. Fujii-Kuriyama Y., Mimura J. Molecular mechanisms of AhR functions in the regulation of cytochrome P450 genes. Biochem. Biophys. Res. Commun. 2005, 338:311-317.
9. Furukawa T., Manabe S., Watanabe T., Sehata S., Sharyo S., Okada T., Mori Y. Daily fluctuation of hepatic P450 monooxygenase activities in male rats is controlled by the suprachiasmatic nucleus but remains unaffected by adrenal hormones. Arch. Toxicol. 1999, 73:367-372.
10. Gery S., Komatsu N., Baldjyan L., Yu A., Koo D., Koeffler H.P. The circadian gene per1 plays an important role in cell growth and DNA damage control in human cancer cells. Mol. Cell 2006, 22:375-382.
11. Gorski J.R., Lebofsky M., Rozman K. Corticosterone decreases toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in hypophysectomized rats. J. Toxicol. Environ. Health 1988, 25:349-360.
12. Hara R., Wan K., Wakamatsu H., Aida R., Moriya T., Akiyama M., Shibata S. Restricted feeding entrains liver clock without participation of the suprachiasmatic nucleus. Genes Cells 2001, 6:269-278.
13. Lee C.C. Tumor suppression by the mammalian Period genes. Cancer Causes Control 2006, 17:525-530.
14. Lee J.E., Safe S. Involvement of a post-transcriptional mechanism in the inhibition of CYP1A1 expression by resveratrol in breast cancer cells. Biochem. Pharmacol. 2001, 62:1113-1124.
15. Levi F., Schibler U. Circadian rhythms: mechanisms and therapeutic implications. Ann. Rev. Pharmacol. Toxicol. 2007, 47:593-628.
16. Lin Y.M., Chang J.H., Yeh K.T., Yang M.Y., Liu T.C., Lin S.F., Su W.W., Chang J.G. Disturbance of circadian gene expression in hepatocellular carcinoma. Mol. Carcinog. 2008, 47:925-933.
17. Lindebro M.C., Poellinger L., Whitelaw M.L. Protein-protein interaction via PAS domains: role of the PAS domain in positive and negative regulation of the bHLH/PAS dioxin receptor-Arnt transcription factor complex. EMBO J. 1995, 14:3528-3539.
18. Metz R.P., Qu X., Laffin B., Earnest D., Porter W.W. Circadian clock and cell cycle gene expression in mouse mammary epithelial cells and in the developing mouse mammary gland. Dev. Dyn. 2006, 235:263-271.
19. Panda S., Antoch M.P., Miller B.H., Su A.I., Schook A.B., Straume M., Schultz P.G., Kay S.A., Takahashi J.S., Hogenesch J.B. Coordinated transcription of key pathways in the mouse by the circadian clock. Cell 2002, 109:307-320.
20. Pollenz R.S. The mechanism of AH receptor protein down-regulation (degradation) and its impact on AH receptor-mediated gene regulation. Chem. Biol. Interact. 2002, 141:41-61.
21. Prough R.A., Linder M.W., Pinaire J.A., Xiao G.H., Falkner K.C. Hormonal regulation of hepatic enzymes involved in foreign compound metabolism. FASEB J. 1996, 10:1369-1377.
22. Qu X., Metz R.P., Porter W.W., Cassone V.M., Earnest D.J. Disruption of clock gene expression alters responses of the AhR signaling pathway in the mouse mammary gland. Mol. Pharm. 2007, 72:1349-1358.
23. Qu X., Metz R.P., Porter W.W., Cassone V.M., Earnest D.J. Disruption of period gene expression alters the inductive effects of dioxin on the AhR signaling pathway in the mouse liver. Tox. Appl. Pharm. 2009, 234:370-377.
24. Reppert S.M., Weaver D.R. Coordination of circadian timing in mammals. Nature 2002, 418:935-941.
25. Richardson V.M., Santostefano M.J., Birnbaum L.S. Daily cycle of bHLH-PAS proteins, Ah receptor and Arnt, in multiple tissues of female Sprague-Dawley rats. Biochem. Biophys. Res. Commun. 1998, 252:225-231.
26. Shearman L.P., Zylka M.J., Weaver D.R., Kolakowski L.F., Reppert S.M. Two period homologs: circadian expression and photic regulation in the suprachiasmatic nuclei. Neuron 1997, 19:1261-1269.
27. Shimizu Y., Nakatsuru Y., Ichinose M., Takahashi Y., Kume H., Mimura J., Fujii-Kuriyama Y., Ishikawa T. Benzo[α]pyrene carcinogenicity is lost in mice lacking the aryl hydrocarbon receptor. Proc. Natl. Acad. Sci. U.S.A. 2000, 97:779-782.
28. Storch K.F., Lipan O., Leykin I., Viswanathan N., Davis F.C., Wong W.H., Weitz C.J. Extensive and divergent circadian gene expression in liver and heart. Nature 2002, 417:78-83.
29. Winter S.L., Bosnoyan-Collins L., Pinnaduwage D., Andrulis I.L. Expression of the circadian clock genes Per1 and Per2 in sporadic and familial breast tumors. Neoplasia 2007, 9:797-800.
30. Yamazaki S., Numano R., Abe M., Hida A., Takahashi R., Ueda M., Block G.D., Sakaki Y., Menaker M., Tei H. Resetting central and peripheral circadian oscillators in transgenic rats. Science 2000, 288:682-685.
31. Zylka M.J., Shearman L.P., Weaver D.R., Reppert S.M. Three period homologs in mammals: differential light responses in the suprachiasmatic circadian clock and oscillating transcripts outside of brain. Neuron 1998, 20:1103-1110.