In chronic viral hepatitis without malignancy, abnormal serum carbohydrate 19-9 antigen levels are associated with liver disease severity and are related to different viral aetiology

Digestive and Liver Disease

Volumn 42, Issue 6, 2010, Pages 458-459

  Bertino, Gaetano ^a   Ardiri, Annalisa M ^a   Calvagno, Giuseppe Stefano ^a   Boemi, Patrizia M ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

Carbohydrate antigen 19 9; Chronic hepatitis; Cirrhosis; Hepatitis B virus; Hepatitis C virus; Liver fibrosis

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA FETOPROTEIN; CA 19-9 ANTIGEN; BIOLOGICAL MARKER;

ADULT; BLOOD LEVEL; DISEASE SEVERITY; FEMALE; HEPATITIS B; HEPATITIS C; HUMAN; LETTER; LIVER BIOPSY; LIVER CIRRHOSIS; LIVER FIBROSIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; BIOPSY; BLOOD; DISEASE COURSE; HEPATITIS B VIRUS; HEPATITIS C VIRUS; HOSPITALIZATION; IMMUNOLOGY; LIVER; MIDDLE AGED; NOTE; PATHOLOGY; VIROLOGY;

BIOLOGICAL MARKERS; BIOPSY; CA-19-9 ANTIGEN; DISEASE PROGRESSION; FEMALE; HEPACIVIRUS; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HEPATITIS C, CHRONIC; HUMANS; LIVER; MALE; MIDDLE AGED; PROGNOSIS; SEVERITY OF ILLNESS INDEX;

EID: 77952743696     PISSN: 15908658     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dld.2009.08.004     Document Type: Letter

References (5)

1. Ventrucci M., Pozzato P., Cipolla A., et al. Persistent elevation of serum CA 19-9 with no evidence of malignant disease. Dig Liver Dis 2009, 41:357-363.
2. Kodama T., Satoh H., Ishikawa H., et al. Serum levels of CA19-9 in patients with nonmalignant respiratory diseases. J Clin Lab Anal 2007, 21:103-106.
3. Sugiyama M., Ito K., Iyonaga K., et al. Idiopathic interstitial pneumonia associated with a high level of CA19-9 in serum and with CA19-9 in lung tissue. Nihon Kyobu Shikkan Gakkai Zasshi 1997, 35:561-565.
4. Kitagawa Y., Iwai M., Muramatsu A., et al. Immunohistochemical localization of CEA, CA19-9 and DU-PAN-2 in hepatitis C virus-infected liver tissues. Histopathology 2002, 40:472-479.
5. Bataller R., Paik Y.H., Lindquist J.N., et al. Hepatitis C virus core and nonstructural proteins induce fibrogenic effects in hepatic stellate cells. Gastroenterology 2004, 126:529-540.