Dynamically-induced spatial dispersion of repolarization and the development of VF in an animal model of sudden death

Computers in Cardiology

Volumn 36, Issue , 2009, Pages 309-312

  Gelzer, Anna R M ^a   Otani, N F ^a   Koller, M L ^b   Enyeart, M W ^a   Moise, N S ^a   Gilmour Jr , R F ^a  

^a Department of Obstetrics Gynecology   (United States)

^b Department of Cardiology ^*  (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTION POTENTIAL DURATIONS; ACTION POTENTIALS; ANIMAL MODEL; APD RESTITUTION; BEAGLE DOG; CONDUCTION BLOCK; IN-VIVO EXPERIMENTS; PREMATURE BEATS; REPOLARIZATION; RIGHT AND LEFT; SPATIAL DISPERSION; SUDDEN DEATHS; VENTRICULAR FIBRILLATION;

CARDIOLOGY;

ANIMALS;

EID: 77952739514     PISSN: 02766574     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (10)

1. Fox JJ, Riccio ML, Drury P, Werthman A, Gilmour Jr RF. Dynamic mechanism for conduction block in heart tissue. New J Phys 2003;5:101.101-101.114.
2. Fox JJ, Riccio ML, Hua F, Bodenschatz E, Gilmour Jr RF. Spatiotemporal transition to conduction block in canine ventricle. Circ Res 2002;90(3):289-296 (Pubitemid 34633930)
3. Otani NF. Theory of action potential wave block at-a-distance in the heart. Phys Rev E Stat Nonlin Soft Matter Phys 2007;75:021910.
4. Gelzer AR, Koller ML, Otani NF, Fox JJ, Enyeart MW, Hooker GJ, Riccio ML, Bartoli CR, Gilmour Jr RF. Dynamic mechanism for initiation of ventricular fibrillation in vivo antifibrillatory effects through modulation of restitution parameters. Circulation 2008;118(11):1123-1129
5. Cordeiro JM, Greene L, Heilmann C, Antzelevitch D, Antzelevitch C. Transmural heterogeneity of calcium activity and mechanical function in the canine left ventricle. Am J Physiol Heart Circ Physiol 2004;286(4):H1471-9.
6. Moise NS, Meyers-Wallen V, Flahive WF, Valentine BA, Scarlett JM, Brown CA, Chavkin MJ, Dugger DA, Renaud- Farrell S, Kornreich B. Inherited ventricular arrhythmias and sudden death in german shepherd dogs. J Am Coll Cardiol 1994;24:233-243.
7. Sosunov EA, Anyukhovsky EP, Hara M, Steinberg SF, Danilo Jr. R, Rosen MR, Moise NS, Merot J, Probst V, Charpentier F, Legeay Y, LeMarec H. Abnormal cardiac repolarization and impulse initiation in german shepherd dogs with inherited ventricular arrhythmias and sudden death. Cardiovasc Res 1999;42:65-79.
8. to in left ventricular myocytes from german shepherd dogs with inherited arrhythmias. J Cardiovasc Electrophysiol 1997;8:872-883
9. Riccio ML, Moise NS, Otani NF, Belina JC, Gelzer ARM, Gilmour RF. Vector quantization of T wave abnormalities associated with a predisposition to ventricular arrhythmias and sudden death. Ann Noninvas Electrocardiol 1998;3:46-53.
10. DaeMW, Lee RJ, Ursell PC, Chin MC, Stillson CA, S MN. Heterogeneous sympathetic innervation in german shepherd dogs with inherited ventricular arrhythmia and sudden cardiac death. Circulation 1997;96(4):1337-1342