Concentrations of Δ9-tetrahydrocannabinol and 11-nor-9-carboxytetrahydrocannabinol in blood and urine after passive exposure to cannabis smoke in a coffee shop

Journal of Analytical Toxicology

Volumn 34, Issue 4, 2010, Pages 196-203

  Rohrich J ^a   Schimmel, I ^b   Zorntlein S ^a   Becker, J ^a   Drobnik, S ^b   Kaufmann, T ^a   Kuntz, V ^a   Urban, R ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CANNABIS; TETRAHYDROCANNABINOL; TETRAHYDROCANNABINOLIC ACID; 11 HYDROXY DELTA(9) TETRAHYDROCANNABINOL; 11 NOR DELTA(9) TETRAHYDROCANNABINOL 9 CARBOXYLIC ACID; 11-HYDROXY-DELTA(9)-TETRAHYDROCANNABINOL; 11-NOR-DELTA(9)-TETRAHYDROCANNABINOL-9-CARBOXYLIC ACID; DRUG DERIVATIVE;

ABSORPTION; ADULT; ARTICLE; BLOOD SAMPLING; CANNABIS SMOKING; CONCENTRATION (PARAMETERS); DERIVATIZATION; FEMALE; HUMAN; HUMAN EXPERIMENT; HYDROLYSIS; IMMUNOASSAY; MALE; MASS FRAGMENTOGRAPHY; NORMAL HUMAN; PASSIVE SMOKING; QUANTITATIVE ANALYSIS; SCREENING TEST; SOLID PHASE EXTRACTION; URINALYSIS; BLOOD; CHEMISTRY; COMPARATIVE STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPOSURE; INDOOR AIR POLLUTION; MIDDLE AGED; NETHERLANDS; REPRODUCIBILITY; SMOKE; STATISTICAL PARAMETERS; TIME; URINE; VALIDATION STUDY;

CANNABIS;

ADULT; AIR POLLUTION, INDOOR; CANNABIS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; INHALATION EXPOSURE; LIMIT OF DETECTION; MALE; MIDDLE AGED; NETHERLANDS; REPRODUCIBILITY OF RESULTS; SMOKE; TETRAHYDROCANNABINOL; TIME FACTORS;

EID: 77952731638     PISSN: 01464760     EISSN: 01464760     Source Type: Journal    
DOI: 10.1093/jat/34.4.196     Document Type: Article

References (16)

1. E.J. Cone, R.E. Johnson, W.D. Darwin, D. Yousefnejad, L.D. Mell, B.D. Paul, and J. Mitchell. Passive inhalation of marijuana smoke: urinalysis and room air levels of delta-9-tetrahydrocannabinol. J. Anal. Toxicol. 11: 89-96 (1987).
2. E.J. Cone and R.E. Johnson. Contact highs and urinary cannabinoid excretion after passive exposure to marijuana smoke. Clin. Pharmacol. Ther. 40: 247-256 (1986).
3. J. Morland, A. Bugge, B. Skuterud, A. Steen, G.H. Wethe, and T. Kjeldsen. Cannabinoids in blood and urine after passive inhalation of Cannabis smoke. J. Forensic Sci. 30: 997-1002 (1985).
4. M. Perez-Reyes, S. Di Guiseppi, A.P. Mason, and K.H. Davis. Passive inhalation of marihuana smoke and urinary excretion of cannabinoids. Clin. Pharmacol. Ther. 34: 36-41 (1983).
5. A.P. Mason, M. Perez-Reyes, A.J. McBay, and R.L. Foltz. Cannabinoid concentrations in plasma after passive inhalation of marijuana smoke. J. Anal. Toxicol. 7: 172-174 (1983).
6. 9-tetrahydrocannabinol-9-carboxylic acid in urine. J. Forensic Sci. 42: 323-325 (1997).
7. G. Skopp and L. Pötsch. Zur Passivexposition bei der Beurteilung niedriger Cannabinoidkonzentrationen in Blut und Urin. Arch. Kriminol. 207: 137-147 (2001).
8. J. Becker, J. Roehrich, and S. Zoerntlein. Simultaneous determination of frequently abused illicit drugs in serum and other body fluids. Rechtsmed. 9 (Suppl. I): A30 (1999).
9. J. Roehrich, S. Zoerntlein, and J. Becker. Analysis of LSD in human body fluids and hair samples applying ImmunElute columns. Forensic Sci. Int. 107: 181-190 (2000).
10. J. Roehrich, S. Zoerntlein, L. Poetsch, G. Skopp, and J. Becker. Effect of the shampoo Ultra Clean on drug concentrations in human hair. Int. J. Legal Med. 113: 102-106 (2000).
11. F.T. Peters and H.H. Maurer. Bioanalytical method validation and its implications for forensic and clinical toxicology-a review. Accred. Qual. Assur. 7: 441-449 (2002).
12. F.T. Peters, O.H. Drummer, and F. Musshoff. Validation of new methods. Forensic Sci. Int. 165: 216-224 (2007).
13. F.T. Peters, M. Hartung, M. Herbold, G. Schmitt, T. Daldrup, and F. Mußhoff. Anlage zu den Richtlinien der GTFCh zur Qualitätssicherung bei forensisch-toxikologischen Unter-suchungen, Anhang C: Anforderungen an die Durchführung von Analysen, 1. Validierung. Toxichem. Krimtech 71: 146-154 (2004).
14. G. Schmitt, M. Herbold, and F. Peters. Methodenvalidierung im Forensisch-Toxikologischen Labor. Arvecon, Walldorf, Germany, 2003.
15. B. Law, P.A. Mason, A.C. Moffat, L.J. King, and V. Marks. Passive inhalation of cannabis smoke. J. Pharm. Pharmacol. 36: 578- 581 (1984).
16. S.J. Mulé, P. Lomax, and S.J. Gross. Active and realistic passive marijuana exposure tested by three immunoassays and GC-MS in urine. J. Anal. Toxicol. 12: 113-116 (1988).