Short-term bone marker responses to teriparatide and strontium ranelate in patients with osteoporosis previously treated with bisphosphonates;Resposta dos marcadores de curto prazo a teriparatida e ranelato de estrôncio em pacientes com osteoporose previamente tratados com bisfosfonatos

Arquivos Brasileiros de Endocrinologia e Metabologia

Volumn 54, Issue 2, 2010, Pages 244-249

  de Sousa, Isabel Oliveira ^a   Diniz, Erik Trovão ^a   Marques, Thyciara Fontenele ^a   Griz, Luiz ^a   de Coutinho, Mário Almeida Pereira ^a   Bandeira, Francisco ^a  

^a FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

Author keywords

Bone remodeling; Osteocalcin; Osteoporosis; Strontium ranelate; Teriparatide; CTX

Indexed keywords

EID: 77952728933     PISSN: 00042730     EISSN: 16779487     Source Type: Journal    
DOI: 10.1590/s0004-27302010000200023     Document Type: Article

References (29)

1. Gandio A, Morabito N. Pharmacological management of severe postmenopausal osteoporosis. Drugs Aging. 2005;22(5):405-17.
2. Shoback D. Update in osteoporosis and metabolic bone disorders. J Clin Endocrinol Metab. 2007;92:747-53.
3. Canalis E, Giustina A, Bilezikian JP. Mechanisms of anabolic therapies for osteoporosis. N Engl J Med. 2007;357(9):905-16.
4. Seeman E. Bone quality: the material and structural basis of bone strength. J Bone Miner Metab. 2008;26(1):1-8.
5. Black D, Greenspan S, Ensrud K, Palermo L, McGowan JA, Lang TF, et al. The effects of parathyroid hormone and alendronate alone or in combination in postmenopausal osteoporosis. N Engl J Med. 2003;349:1207-15.
6. Hammett-Stabler CA. The use of biochemical markers in osteoporosis. Clin Lab Med. 2004;24:175-97.
7. Muenier PJ, Roux C, Seeman E, Ortolani S, Badurski JE, et al. The effect of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis. N Engl J Med. 2004;350:459-68.
8. Reginster JY, Seeman E, Vernejoul MC, Adami S, Compston J, et al. Strontium ranelate reduces risk of nonvertebral fractures in postmenopausal women with osteoporosis: Treatment of Peripheral Osteoporosis (TROPOS) study. J Clin Endocrinol Metab. 2005;90(5):2816-22.
9. Delmas PD. Markers of bone turnover for monitoring treatment of osteoporosis with antiresorptive drugs. Osteoporos Int. 2000;11:Suppl 6:S66-76.
10. Alexandersen P, Peris P, Guañabens N, Byrjalsen I, Alvarez L, Solberg H, et al. Non-isomerized C-telopeptide fragments are highly sensitive markers for monitoring disease activity and treatment efficacy in paget's disease of bone. J Bone Miner Res. 2005;20(4):588-95.
11. Delmas PD, Vrijens B, Eastell R, Roux C, Pols HA, Ringe JD, et al. Effect of monitoring bone turnover markers on persistence with risedronate treatment of postmenopausal osteoporosis. J Clin Endocrinol Metab. 2007;92:1296-304
12. Reginster JY, Collette J, Neuprez A, Zegels B, Deroisy R, Bruyere O. Role of biochemical markers of bone turnover as a prognostic indicator of successful osteoporosis therapy. Bone. 2008;42(5):832-6.
13. Cosman F, Linasay R. Therapeutic potential of parathyroid hormone. Curr Osteoporos Rep. 2004;2(1):5-11.
14. Greenspan SL, Bone HG, Ettinger MP, Hanley DA, Lindsay R, Zanchetta JR, et al. Effect of recombinant human parathyroid hormone (1-84) on vertebral fracture and bone mineral density in postmenopausal women with osteoporosis: a randomized trial. Ann Intern Med. 2007;146(5):326-39.
15. Boonen S, Marin F, Obermayer-Pietsch B, Simões ME, Barker C, Glass EV, et al. Effects of previous antiresorptive therapy on the bone mineral density response to two years of teriparatide treatment in postmenopausal women with osteoporosis. J Clin Endocrinol Metab. 2008;93(3):852-60.
16. Burr DB. Does early PTH treatment compromise bone strength? The balance between remodeling, porosity, bone mineral, and bone size. Curr Osteoporos. 2005;3(1):19-24.
17. McClung MR, Sam Martin J, Miller PD, Civitelli R, Bandeira F, Omizo M, et al. Opposite bone remodeling effects of teriparatide and alendronate in increasing bone mass. Arch Intern Med. 2005;165(15):1762-8.
18. Black DM, Bouxsein ML, Palermo L, McGowan JA, Newitt D, Rosen E, et al. Randomized trial of once-weekly PTH (1-84) on bone mineral density and remodeling. J Clin Endocrinol Metab. 2008;93(6):2166-72. [Epub 2008 Mar 18]
19. Dobnig H, Sipos A, Jiang Y, Fahrleitner-Pammer A, Ste-Marie LG, Gallagher JC, et al. Early changes in biochemical markers of bone formation correlate with improvements in bone structure during teriparatide therapy. J Clin Endocrinol Metab. 2005;90:3970-7.
20. Bauer DC, Garnero P, Bilezikian JP, Greenspan SL, Ensrud KE, Rosen CJ, et al. Short-term changes in bone turnover markers and bone mineral density response to parathyroid hormone in post menopausal women with osteoporosis. J Clin Endocrinol Metab. 2006;91(4):1370-5.
21. Hodsman D, Hanley M, Ettinger MP, Bolognese MA, Fox J, Metcalfe AJ, et al. Efficacy and safety of human parathyroid hormone (1-84) in increasing bone mineral density in postmenopausal osteoporosis. J Clin Endocrinol Metab. 2003;88(11):5212-20.
22. Finkelstein JS, Leder BZ, Burnett SM, Wyland JJ, Lee H, de la Paz AV, et al. Effects of teriparatide, alendronate, or both on bone turnover in osteoporotic men. J Clin Endocrinol Metab. 2006;91(8):2882-7.
23. Graeff C, Timm W, Nickelsen NT, Farrerons J, Marín F, Barker C, et al. Monitoring teriparatide-associated changes in vertebral microstructure by high-resolution CT in vivo: results from the EUROFORS study. J Bone Miner Res. 2007;22:1426-33.
24. Black DM, Schwartz AV, Ensrud KE, Cauley JA, Levis S, Quandft SA, et al. Effects of continuing or stopping alendronate after 5 years of treatment: The Fracture Intervention Trial Long-Term Extension (FLEX): A randomized trial. JAMA. 2006;296(24):2927-38.
25. Bruyère O, Collette J, Rizzoli R, et al. Relationship between 3-month changes in biochemical markers of bone remodeling and changes in bone mineral density and fracture incidence in patients treated with strontium ranelate for 3 years. Osteoporos Int. 2009 Oct 8. [Epub ahead of print]
26. Recker RR, Marin F, Ish-Shalom S, et al. Comparative effects of tereparatide and strontium ranelate on bone biopsies and biochemical markers of bone turnover in postmenopausal women with osteoporosis. J Bone Miner Res. 2009;24(08):1358-68.
27. Reginster JY, Deroisy R, Dougados M, et al. Prevention of early postmenopausal bone loss by strontium ranelate: the randomized two-year, double-masked, dose ranging, placebo-controlled PREVOS study. Osteoporos Int. 2002;13:925-31.
28. Meunier PJ, Slosman DO, Delmas PD, et al. Strontium ranelate: dose-dependent effects in established postmenopausal vertebral osteoporosis - a two-year randomized placebo controlled trial. J Clin Endocrinal Metab. 2002;87:2060-6.
29. Blake GM, Compston JE, Fogelman I. Could strontium ranelate have a synergistic role in the treatment of osteoporosis? J Bone Miner Res. 2009;24(08):1354-7.