Fibrin Glue Is Effective Healing Perianal Fistulas in Patients with Crohn's Disease

Gastroenterology

Volumn 138, Issue 7, 2010, Pages

  Grimaud, Jean Charles ^a   Munoz Bongrand, Nicolas ^b   Siproudhis, Laurent ^c   Abramowitz, Laurent ^d   Sénéjoux, Agnès ^e   Vitton, Véronique ^a   Gambiez, Luc ^f   Flourié, Bernard ^g   Hébuterne, Xavier ^h   Louis, Edouard ⁱ   Coffin, Benoit ^j   De Parades, Vincent ^k   Savoye, Guillaume ^l   Soulé, Jean Claude ^d   Bouhnik, Yoram ^e   Colombel, Jean Frédéric ^f   Contou, Jean François ^m   François, Yves ^g   Mary, Jean Yves ^b   Lémann, Marc ^b  

^a HÔPITAL NORD   (France)

^b SAINT LOUIS HOSPITAL   (France)

^c UNIVERSITÉ DE RENNES 1   (France)

^d BICHAT HOSPITAL   (France)

^e BEAUJON HOSPITAL   (France)

^f UNIV LILLE   (France)

^g UNIVERSITÉ LYON 1   (France)

^h CENTRE HOSPITALIER UNIVERSITAIRE DE NICE   (France)

ⁱ UNIVERSITY OF LIÈGE   (Belgium)

^j HÔPITAL LOUIS MOURIER   (France)

^k HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^l UNIVERSITÉ DE ROUEN   (France)

^m HÔPITAL SAINT ANTOINE   (France)

more..

Author keywords

Controlled Trial; Crohn's Disease; Fibrin Therapy; Perianal Fistula

Indexed keywords

AMINOSALICYLIC ACID DERIVATIVE; AZATHIOPRINE; BUDESONIDE; CORTICOSTEROID; FIBRIN GLUE; INFLIXIMAB; MERCAPTOPURINE; METHOTREXATE; PREDNISONE; THALIDOMIDE;

ADULT; ANUS FISTULA; ARTICLE; CLINICAL OBSERVATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROHN DISEASE; DISEASE ACTIVITY; ENDOSCOPIC ECHOGRAPHY; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NUCLEAR MAGNETIC RESONANCE IMAGING; OPEN STUDY; OUTCOME ASSESSMENT; PATIENT SAFETY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REMISSION; SURGICAL DRAINAGE;

EID: 77952715586     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2010.02.013     Document Type: Article

References (33)

1. Hellers G., Bergstrand O., Ewerth S., et al. Occurrence and outcome after primary treatment of anal fistulae in Crohn's disease. Gut 21 (1980) 525-527
2. Schwartz D.A., Loftus E.V., Tremaine W.J., et al. The natural history of fistulizing Crohn's disease in Olmsted County, Minnesota. Gastroenterology 122 (2002) 875-880
3. Schwartz D.A., Pemberton J.H., and Sandborn W.J. Diagnosis and treatment of perianal fistulas in Crohn's disease. Ann Intern Med 135 (2001) 906-918
4. Pescatori M., Interisano A., and Basso L. Management of perianal Crohn's disease. Dis Colon Rectum 38 (1995) 121-124
5. Bernstein L.H., Frank M.S., Brandt L.J., et al. Healing of perineal Crohn's disease with metronidazole. Gastroenterology 79 (1980) 357-365
6. Present D.H., Korelitz B., Wisch N., et al. Treatment of Crohn's disease with 6-mercaptopurine: a long-term randomized double blind study. N Engl J Med 302 (1980) 981-987
7. Pearson D.C., May G.R., Fick G.H., et al. Azathioprine and 6-mercaptopurine in Crohn's disease. A meta-analysis. Ann Intern Med 123 (1995) 132-142
8. Hanauer S.B., and Smith M.B. Rapid closure of Crohn's disease fistulas with continuous intravenous cyclosporine A. Am J Gastroenterol 88 (1993) 646-649
9. Sandborn W.J., Present D.H., Isaacs K.L., et al. Tacrolimus for the treatment of fistulas in patients with Crohn's disease: a randomized, placebo-controlled trial. Gastroenterology 125 (2003) 380-388
10. Present D.H., Rutgeerts P., Targan S., et al. Infliximab for the treatment of fistulas in patients with Crohn's disease. N Engl J Med 340 (1999) 1398-1405
11. Sands B.E., Anderson F.H., Bernstein C.N., et al. Infliximab maintenance therapy for fistulizing Crohn's disease. N Engl J Med 350 (2004) 876-885
12. Colombel J.F., Sandborn W.J., Rutgeerts P., et al. Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: the CHARM trial. Gastroenterology 132 (2007) 52-65
13. Van Assche G., Vanbeckevoort D., Bielen D., et al. Magnetic resonance imaging of the effects of infliximab on perianal fistulizing Crohn's disease. Am J Gastroenterol 98 (2003) 332-339
14. Williams J.G., Rothenberger D.A., Nemer F.D., et al. Fistula-in-ano in Crohn's disease. Results of aggressive surgical treatment. Dis Colon Rectum 34 (1991) 378-384
15. Zimmerman D.D., Briel J.W., Gosselink M.P., et al. Anocutaneous advancement flap repair of transsphincteric fistulas. Dis Colon Rectum 44 (2001) 1474-1480
16. Joo J.S., Weiss E.G., Nogueras J.J., et al. Endorectal advancement flap in perianal Crohn's disease. Ann Surg 64 (1998) 147-150
17. Garcia-Aguilar J., Belmonte C., Wong W.D., Goldberg S.M., et al. Anal fistula surgery: factors associated with recurrence and incontinence. Dis Colon Rectum 39 (1996) 723-729
18. Horjtrup A., Moesgaard F., and Kjaegard J. Fibrin adhesive in the treatment of perianal fistulas. Dis Colon Rectum 34 (1991) 752-754
19. Abel M.E., Chiu Y.S., Russel T.R., et al. Autologus fibrin glue in the treatment of rectovaginal and complex fistulas. Dis Colon Rectum 36 (1993) 447-449
20. Venkatesch K.S., and Ramanujam P. Fibrin glue application in the treatment of recurrent anorectal fistulas. Dis Colon Rectum 42 (1999) 1136-1139
21. Cintron J.R., Park J.J., Orsay C.P., et al. Repair of fistulas-in-ano using fibrin adhesive: long-term follow-up. Dis Colon Rectum 43 (2000) 944-949
22. Park J.J., Cintron J.R., Orsay C.P., et al. Repair of chronic anorectal fistulae using commercial fibrin sealant. Arch Surg 135 (2000) 166-169
23. Partjl M., Kocman B., Martinae M., et al. Fibrin glue-antibiotics mixture in the treatment of anal fistulae: experience with 69 cases. Dig Surg 17 (2000) 77-80
24. Sentovitch S.M. Fibrin glue for anal fistulas. J Gastrointest Surg 5 (2001) 158-161
25. Loungnarath R., Dietz D.W., Mutch M.G., et al. Fibrin glue treatment of complex anal fistulas have low success rate. Dis Colon Rectum 47 (2004) 432-436
26. Singer M., Cintron J., Nelson R., et al. Treatment of fistulas-in-ano with fibrin sealant in combination with intra-adhesive antibiotics and/or surgical closure of the internal fistula opening. Dis Colon Rectum 48 (2005) 799-808
27. Zmora O., Neufeld D., Ziv Y., et al. Prospective, multicenter evaluation of highly concentrated fibrin glue in the treatment of complex cryptogenic perianal fistulas. Dis Colon Rectum 48 (2005) 2167-2172
28. Maraclan G., Baskonu Y., Aybasti N., et al. The use of fibrin glue in the treatment of fistula-in-ano: a prospective study. Surg Today 36 (2006) 166-170
29. de la Portilla F., Rada R., Leon E., et al. Evaluation of the use of BioGlue in the treatment of high anal fistulas: preliminary result of a pilot study. Dis Colon Rectum 50 (2006) 1-5
30. Vitton V., Gasmi M., Barthet M., et al. Long-term healing of Crohn's anal fistulas with fibrin glue injection. Aliment Pharmacol Ther 21 (2005) 1453-1457
31. Johnson E.K., Gaw J., and Armstrong D.N. Efficacy of anal fistula plug vs fibrin glue in closure of anorectal fistulas. Dis Colon Rectum 49 (2006) 371-376
32. Ellis N., and Clark S. Fibrin glue as an adjunct to flap repair of anal fistulas: a randomized controlled study. Dis Colon Rectum 49 (2006) 1736-1740
33. Orsoni P., Barthet M., Portier F., et al. Prospective comparison between endosonography, magnetic resonance imaging and surgical exploration in the assessment of anorectal fistulas and abcesses complicating Crohn's disease. Br J Surg 86 (1999) 360-364