Immunotherapeutic effect of anti-PrP monoclonal antibodies in transmissible spongiform encephalopathy mouse models: Pharmacokinetic and pharmacodynamic analysis

Journal of General Virology

Volumn 91, Issue 6, 2010, Pages 1635-1645

  Féraudet Tarisse, Cécile ^a,b   Andréoletti, Olivier ^a   Morel, Nathalie ^b   Simon, Stéphanie ^b   Lacroux, Caroline ^a   Mathey, Jacinthe ^a   Lamourette, Patricia ^b   Relaño, Aroa ^c   Torres, Juan Maria ^c   Créminon, Christophe ^b   Grassi, Jacques ^b  

^a UNIVERSITÉ DE TOULOUSE   (France)

^b SERVICE DE CHIMIE BIOORGANIQUE ET DE MARQUAGE   (France)

^c Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY; PRION PROTEIN; PRION PROTEIN ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE TRANSMISSION; DRUG EFFECT; DRUG EFFICACY; MOUSE; NONHUMAN; PHARMACODYNAMICS; PRION; PRION DISEASE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; SURVIVAL RATE; THERAPY;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGEN-ANTIBODY COMPLEX; DISEASE MODELS, ANIMAL; IMMUNOTHERAPY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PRION DISEASES; PRPC PROTEINS; SURVIVAL ANALYSIS; TIME FACTORS; TREATMENT OUTCOME;

ANIMALIA; MUS;

EID: 77952709638     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.018077-0     Document Type: Article

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