Endoplasmic reticulum stress inhibits collagen synthesis independent of collagen-modifying enzymes in different chondrocyte populations and dermal fibroblasts

Biochemistry and Cell Biology

Volumn 88, Issue 3, 2010, Pages 539-552

  Vonk, Lucienne A ^a   Doulabi, Behrouz Zandieh ^b   Huang, Chun Ling ^a   Helder, Marco N ^b   Everts, Vincent ^a   Bank, Ruud A ^a,c  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Cartilage; Chondrocyte; Endoplasmic reticulum (ER) stress; Fibroblast; Intervertebral disc

Indexed keywords

CHONDROCYTES; ENDOPLASMIC RETICULUM (ER) STRESS; ENDOPLASMIC RETICULUM STRESS; INTERVERTEBRAL DISC; INTERVERTEBRAL DISCS;

ANTIBIOTICS; BODY FLUIDS; CARTILAGE; CATALYSTS; CELL CULTURE; CELL DEATH; COLLAGEN; ENZYMES; FIBROBLASTS; GENE EXPRESSION; GLUCOSE; LIGAMENTS; SYNTHESIS (CHEMICAL);

GENE EXPRESSION REGULATION;

CHAPERONE; COLLAGEN; N PROPEPTIDASE ADAMTS2; PEPTIDASE; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; TUNICAMYCIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CELL POPULATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION REGULATION; GLUCOSE METABOLISM; INTERVERTEBRAL DISK; KNEE MENISCUS; NONHUMAN; NUCLEUS PULPOSUS; PROTEIN FUNCTION; PROTEIN MODIFICATION; SKIN FIBROBLAST; UPREGULATION;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CARTILAGE; CELLS, CULTURED; CHONDROCYTES; COLLAGEN; DERMIS; ENDOPLASMIC RETICULUM; FIBROBLASTS; MICROSCOPY, FLUORESCENCE; POLYMERASE CHAIN REACTION; STRESS, PHYSIOLOGICAL;

EID: 77952691533     PISSN: 08298211     EISSN: 12086002     Source Type: Journal    
DOI: 10.1139/O09-174     Document Type: Article

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