Myristoylation of the dual-specificity phosphatase c-JUN N-terminal kinase (JNK) stimulatory phosphatase 1 is necessary for its activation of JNK signaling and apoptosis

FEBS Journal

Volumn 277, Issue 11, 2010, Pages 2463-2473

  Schwertassek, Ulla ^a   Buckley, Deirdre A ^a   Xu, Chong Feng ^b   Lindsay, Andrew J ^c   McCaffrey, Mary W ^c   Neubert, Thomas A ^b   Tonks, Nicholas K ^a  

^a Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

Apoptosis; JNK; JSP1; Myristoylation; Phosphatase

Indexed keywords

ALANINE; GLYCINE; PHOSPHOPROTEIN PHOSPHATASE; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE STIMULATORY PHOSPHATASE 1; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL COUNT; CELL CULTURE; CELL STRAIN COS1; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; GENETIC TRANSFECTION; HELA CELL; HUMAN; IMMUNOBLOTTING; MASS SPECTROMETRY; MICROSCOPY; MUTANT; MYRISTYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SIGNAL TRANSDUCTION; WILD TYPE;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; CELL DEATH; CELL SURVIVAL; DUAL-SPECIFICITY PHOSPHATASES; EMBRYONIC DEVELOPMENT; ENZYME ACTIVATION; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAMMALS; MASS SPECTROMETRY; MITOGEN-ACTIVATED PROTEIN KINASE PHOSPHATASES; MORPHOGENESIS; MYRISTIC ACID; PHOSPHOPROTEIN PHOSPHATASES; PHOSPHOSERINE; PHOSPHOTHREONINE; PHOSPHOTYROSINE; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY; TRANSFECTION;

EID: 77952685704     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2010.07661.x     Document Type: Article

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