Structure of the 70S ribosome bound to release factor 2 and a substrate analog provides insights into catalysis of peptide release

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 19, 2010, Pages 8593-8598

  Jin, Hong ^a   Kelley, Ann C ^a   Loakes, David ^a   Ramakrishnan, V ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

Ribosome structure; Translational termination; X ray crystallography

Indexed keywords

AMINOACYL TRANSFER RNA; GLUTAMINE; PEPTIDYLTRANSFERASE; RELEASE FACTOR 2; RIBOSOME PROTEIN; RNA 23S; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN MOTIF; PROTEIN SECRETION; PROTEIN STRUCTURE; RIBOSOME; STOP CODON; THERMUS THERMOPHILUS;

AMINO ACID MOTIFS; BIOCATALYSIS; GLUTAMINE; HYDROXYL RADICAL; MODELS, BIOLOGICAL; MODELS, MOLECULAR; NUCLEOTIDES; PEPTIDE CHAIN TERMINATION, TRANSLATIONAL; PEPTIDE TERMINATION FACTORS; PEPTIDES; PEPTIDYL TRANSFERASES; RIBOSOMES; RNA, TRANSFER, AMINO ACYL; SUBSTRATE SPECIFICITY; THERMUS THERMOPHILUS; WATER;

EID: 77952685666     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1003995107     Document Type: Article

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