Disturbance of mitochondrial energy homeostasis caused by the metabolites accumulating in LCHAD and MTP deficiencies in rat brain

Life Sciences

Volumn 86, Issue 21-22, 2010, Pages 825-831

  Tonin, Anelise M ^a   Ferreira, Gustavo C ^a   Grings, Mateus ^a   Viegas, Carolina M ^a   Busanello, Estela N ^a   Amaral, Alexandre U ^a   Zanatta, Ângela ^a   Schuck, Patrícia Fernanda ^a,c   Wajner, Moacir ^a,b  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

^c UNIVERSIDADE DO EXTREMO SUL CATARINENSE   (Brazil)

Author keywords

Brain bioenergetics; LCHAD deficiency; Long chain 3 hydroxy fatty acids; MTP deficiency

Indexed keywords

3 HYDROXYACYL COENZYME A DEHYDROGENASE; 3 HYDROXYDODECANOIC ACID; 3 HYDROXYMYRISTIC ACID; 3 HYDROXYPALMITIC ACID; FATTY ACID; GLUTAMIC ACID; LAURIC ACID; MALIC ACID; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL TRIFUNCTIONAL PROTEIN; PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SUCCINIC ACID; UNCLASSIFIED DRUG;

3 HYDROXYACYL COENZYME A DEHYDROGENASE DEFICIENCY; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN HOMOGENATE; BRAIN MITOCHONDRION; CELL ENERGY; CONTROLLED STUDY; ENZYME DEFICIENCY; FOREBRAIN; HOMEOSTASIS; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MITOCHONDRIAL TRIFUNCTIONAL PROTEIN DEFICIENCY; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PROTEIN DEFICIENCY; PROTEIN DETERMINATION; RAT;

3-HYDROXYACYL COA DEHYDROGENASES; ANIMALS; BRAIN; ENERGY METABOLISM; HOMEOSTASIS; LAURIC ACIDS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MULTIENZYME COMPLEXES; MYRISTIC ACIDS; NADP; OXYGEN CONSUMPTION; RATS; RATS, WISTAR;

RATTUS;

EID: 77952673083     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2010.04.003     Document Type: Article

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