Nano is better than micro for targeted vaccine delivery

Journal of Controlled Release

Volumn 144, Issue 2, 2010, Pages 117-

  Park, Kinam ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; DRUG CARRIER; MICROPARTICLE; NANOCARRIER; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VACCINE;

ANTIGEN SPECIFICITY; CONTROLLED DRUG RELEASE; DEGRADATION KINETICS; DENDRITIC CELL; DRUG EFFICACY; DRUG PENETRATION; EDITORIAL; HUMAN; IMMUNE RESPONSE; IMMUNOMODULATION; MICROENCAPSULATION; NANOENCAPSULATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; VACCINATION;

DRUG DELIVERY SYSTEMS; HUMANS; NANOSTRUCTURES;

EID: 77952669649     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.04.022     Document Type: Editorial

References (4)

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2. Manolova V., Flace A., Bauer M., Schwarz K., Saudan P., Bachmann M.F. Nanoparticles target distinct dendritic cell populations according to their size. Eur. J. Immunol. 2008, 38:1404-1413.
3. Cruz L.J., Tacken P.J., Fokkink R., Joosten B., Stuart M.C., Albericio F., Torensma R., Figdor C.G. Targeted PLGA nano- but not microparticles specifically deliver antigen to human dendritic cells via DC-SIGN in vitro. J. Control. Release 2010, 144:118-126.
4. Mundargi R.C., Babu V.R., Rangaswamy V., Patel P., Aminabhavi T.M. Nano/micro technologies for delivering macromolecular therapeutics using poly(d, l-lactide-co-glycolide) and its derivatives. J. Control. Release 2008, 125:193-209.