Molecular characterization of β-lactamase genes and their genetic structures in acinetobacter genospecies 3 isolates in Taiwan

Antimicrobial Agents and Chemotherapy

Volumn 54, Issue 6, 2010, Pages 2699-2703

  Huang, Li Yueh ^a   Lu, Po Liang ^b,c   Chen, Te Li ^d,e   Chang, Fang Yee ^a,f   Fung, Chang Phone ^d   Siu, L K ^a,f,g  

^a NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^d TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^e NATIONAL YANG MING UNIVERSITY   (Taiwan)

^f TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^g NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; AZTREONAM; BETA LACTAMASE; CEFEPIME; CEFTAZIDIME; CEFTRIAXONE; CEPHALOSPORINASE; CIPROFLOXACIN; COLISTIN; GENTAMICIN; IMIPENEM; INTEGRASE; MEROPENEM; PIPERACILLIN; PIPERACILLIN PLUS TAZOBACTAM; PROTEIN IMP1; PROTEIN IMP8; PROTEIN OXA58; PROTEIN VEB3; SULBACTAM; SULTAMICILLIN; TIGECYCLINE; TOBRAMYCIN; UNCLASSIFIED DRUG;

ACINETOBACTER; ACINETOBACTER GENOSPECIES 3; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM ISOLATE; BLA ADC GENE; BLA IMP1 GENE; BLA IMP8 GENE; BLA OXA58 GENE; BLA VEB3 GENE; FOLE GENE; GENETIC VARIABILITY; INTEGRON; ISABA3 GENE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; TAIWAN;

ACINETOBACTER; ACINETOBACTER INFECTIONS; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; CEPHALOSPORINASE; GENE TRANSFER, HORIZONTAL; GENES, BACTERIAL; HUMANS; INTEGRONS; MICROBIAL SENSITIVITY TESTS; MOLECULAR EPIDEMIOLOGY; MOLECULAR SEQUENCE DATA; PHYLOGENY; TAIWAN;

EID: 77952666088     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01624-09     Document Type: Article

References (38)

1. Adams, M. D., K. Goglin, N. Molyneaux, K. M. Hujer, H. Lavender, J. J. Jamison, I. J. MacDonald, K. M. Martin, T. Russo, A. A. Campagnari, A. M. Hujer, R. A. Bonomo, and S. R. Gill. 2008. Comparative genome sequence analysis of multidrug-resistant Acinetobacter baumannii. J. Bacteriol. 190: 8053-8064.
2. Beceiro, A., A. Perez, F. Fernandez-Cuenca, L. Martinez-Martinez, A. Pascual, J. Vila, J. Rodriguez-Bano, J. M. Cisneros, J. Pachon, and G. Bou. 2009. Genetic variability among ampC genes from Acinetobacter genomic species 3. Antimicrob. Agents Chemother. 53:1177-1184.
3. Boo, T. W., F. Walsh, and B. Crowley. 2009. Molecular characterization of carbapenem-resistant Acinetobacter species in an Irish university hospital: predominance of Acinetobacter genomic species 3. J. Med. Microbiol. 58: 209-216.
4. Chu, Y. W., C. M. Leung, E. T. Houang, K. C. Ng, C. B. Leung, H. Y. Leung, and A. F. Cheng. 1999. Skin carriage of acinetobacters in Hong Kong. J. Clin. Microbiol. 37:2962-2967.
5. Clinical and Laboratory Standards Institute. 2009. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically, vol. 29, no. 2. Approved standard M07-A8. Clinical and Laboratory Standards Institute, Wayne, PA.
6. Clinical and Laboratory Standards Institute. 2009. Performance standards for antimicrobial susceptibility testing, vol. 29, no. 3. Approved standard M100-S19. Clinical and Laboratory Standards Institute, Wayne, PA.
7. El Yacoubi, B., S. Bonnett, J. N. Anderson, M. A. Swairjo, D. Iwata-Reuyl, and V. de Crecy-Lagard. 2006. Discovery of a new prokaryotic type I GTP cyclohydrolase family. J. Biol. Chem. 281:37586-37593.
8. Ellington, M. J., J. Kistler, D. M. Livermore, and N. Woodford. 2007. Multiplex PCR for rapid detection of genes encoding acquired metallo-beta-lactamases. J. Antimicrob. Chemother. 59:321-322.
9. Falagas, M. E., and D. E. Karageorgopoulos. 2008. Pandrug resistance (PDR), extensive drug resistance (XDR), and multidrug resistance (MDR) among Gram-negative bacilli: need for international harmonization in terminology. Clin. Infect. Dis. 46:1121-1122.
10. Fournier, P. E., D. Vallenet, V. Barbe, S. Audic, H. Ogata, L. Poirel, H. Richet, C. Robert, S. Mangenot, C. Abergel, P. Nordmann, J. Weissenbach, D. Raoult, and J. M. Claverie. 2006. Comparative genomics of multidrug resistance in Acinetobacter baumannii. PLoS. Genet. 2:e7.
11. Heuer, H., C. Kopmann, C. T. Binh, E. M. Top, and K. Smalla. 2009. Spreading antibiotic resistance through spread manure: characteristics of a novel plasmid type with low %G+C content. Environ. Microbiol. 11:937-949.
12. IMP-4) gene cassettes in class 1 integrons in Acinetobacter strains isolated from blood cultures in 1997 to 2000. Antimicrob. Agents Chemother. 47:1382-1390.
13. Huang, L. Y., T. L. Chen, P. L. Lu, C. A. Tsai, W. L. Cho, F. Y. Chang, C. P. Fung, and L. K. Siu. 2008. Dissemination of multidrug-resistant, class 1 integron-carrying Acinetobacter baumannii isolates in Taiwan. Clin. Microbiol. Infect. 14:1010-1019.
14. Koeleman, J. G., J. Stoof, M. W. van der Bijl, C. M. Vandenbroucke- Grauls, and P. H. Savelkoul. 2001. Identification of epidemic strains of Acinetobacter baumannii by integrase gene PCR. J. Clin. Microbiol. 39:8-13.
15. Krawczyk, B., K. Lewandowski, and J. Kur. 2002. Comparative studies of the Acinetobacter genus and the species identification method based on the recA sequences. Mol. Cell Probes 16:1-11.
16. La Scola, S. B., V. A. Gundi, A. Khamis, and D. Raoult. 2006. Sequencing of the rpoB gene and flanking spacers for molecular identification of Acinetobacter species. J. Clin. Microbiol. 44:827-832.
17. Larkin, M. A., G. Blackshields, N. P. Brown, R. Chenna, P. A. McGettigan, H. McWilliam, F. Valentin, I. M. Wallace, A. Wilm, R. Lopez, J. D. Thompson, T. J. Gibson, and D. G. Higgins. 2007. Clustal W and Clustal X version 2.0. Bioinformatics 23:2947-2948.
18. Lim, Y. M., K. S. Shin, and J. Kim. 2007. Distinct antimicrobial resistance patterns and antimicrobial resistance-harboring genes according to genomic species of Acinetobacter isolates. J. Clin. Microbiol. 45:902-905.
19. Livermore, D. M., and N. Woodford. 2006. The β-lactamase threat in Enterobacteriaceae, Pseudomonas and Acinetobacter. Trends Microbiol. 14:413-420.
20. Lu, P. L., L. Y. Huang, S. T. Lian, K. Chang, C. L. Lin, I. J. Hwang, W. G. Chiang, Y. H. Chen, S. F. Lin, and L. K. Siu. 2008. How carbapenem-resistant Acinetobacter spp. established in a newly constructed hospital. Int. J. Antimicrob. Agents 31:463-466.
21. Ma, L., J. Alba, F.-Y. Chang, M. Ishiguro, K. Yamaguchi, L. K. Siu, and Y. Ishii. 2005. Novel SHV-derived extended-spectrum β-lactamase, SHV-57, that confers resistance to ceftazidime but not cefazolin. Antimicrob. Agents Chemother. 49:600-605.
22. Marti, S., J. Sanchez-Cespedes, M. D. Blasco, M. Ruiz, P. Espinal, V. Alba, F. Fernandez-Cuenca, A. Pascual, and J. Vila. 2008. Characterization of the carbapenem-hydrolyzing oxacillinase Oxa-58 in an Acinetobacter genospecies 3 clinical isolate. Antimicrob. Agents Chemother. 52:2955-2958.
23. Miembros del grupo MENSURA. 2000. Recommendations from MENSURA for selection of antimicrobial agents for susceptibility testing and criteria for the interpretation of antibiograms. Rev. Esp. Quimioter. 13:73-86.
24. Naas, T., P. Bogaerts, C. Bauraing, Y. Degheldre, Y. Glupczynski, and P. Nordmann. 2006. Emergence of PER and VEB extended-spectrum-β-lactamases in Acinetobacter baumannii in Belgium. J. Antimicrob. Chemother. 58:172-182.
25. Pankey, G. A. 2005. Tigecycline. J. Antimicrob. Chemother. 56:470-480.
26. Peleg, A. Y., H. Seifert, and D. L. Paterson. 2008. Acinetobacter baumannii: emergence of a successful pathogen. Clin. Microbiol. Rev. 21:538-582.
27. Poirel, L., and P. Nordmann. 2006. Carbapenem resistance in Acinetobacter baumannii: mechanisms and epidemiology. Clin. Microbiol. Infect. 12:826-836.
28. Poirel, L., S. Figueiredo, V. Cattoir, A. Carattoli, and P. Nordmann. 2008. Acinetobacter radioresistens as a silent source of carbapenem resistance for Acinetobacter spp. Antimicrob. Agents Chemother. 52:1252-1256.
29. EB gene acquisition. Antimicrob. Agents Chemother. 53:4940-4943.
30. XA-58 in Acinetobacter baumannii. Antimicrob. Agents Chemother. 50: 1442-1448.
31. Ruiz, M., S. Marti, F. Fernandez-Cuenca, A. Pascual, and J. Vila. 2007. Prevalence of ISAba1 in epidemiologically unrelated Acinetobacter baumannii clinical isolates. FEMS Microbiol. Lett. 274:63-66.
32. Tjernberg, I., and J. Ursing. 1989. Clinical strains of Acinetobacter classified by DNA-DNA hybridization. APMIS 97:595-605.
33. Tsakris, A., A. Ikonomidis, S. Pournaras, L. S. Tzouvelekis, D. Sofianou, N. J. Legakis, and A. N. Maniatis. 2006. VIM-1 metallo-beta-lactamase in Acinetobacter baumannii. Emerg. Infect. Dis. 12:981-983.
34. Woodford, N., M. J. Ellington, J. M. Coelho, J. F. Turton, M. E. Ward, S. Brown, S. G. Amyes, and D. M. Livermore. 2006. Multiplex PCR for genes encoding prevalent OXA carbapenemases in Acinetobacter spp. Int. J. Antimicrob. Agents 27:351-353.
35. Yeh, K. M., A. Kurup, L. K. Siu, Y. L. Koh, C. P. Fung, J. C. Lin, T. L. Chen, F. Y. Chang, and T. H. Koh. 2007. Capsular serotype K1 or K2, rather than magA and rmpA, is a major virulence determinant for Klebsiella pneumoniae liver abscess in Singapore and Taiwan. J. Clin. Microbiol. 45:466-471.
36. VIM-2 gene cassettes. J. Antimicrob. Chemother. 49:837-840.
37. OXA-58 gene confers imipenem resistance to Acinetobacter baumannii isolates from a Lebanese hospital. Antimicrob. Agents Chemother. 52:4115-4120.
38. VEB-1 variant, blaVEB-6, associated with repeated elements in a complex genetic structure. Antimicrob. Agents Chemother. 53:1693-1697.