Sol-gel-derived glass scaffold with high pore interconnectivity and enhanced bioactivity

Journal of Materials Research

Volumn 24, Issue 12, 2009, Pages 3495-3502

  Marques, Ana C ^a,d   Almeida, Rui M ^a   Thiema, Amath ^b,e   Wang, Shaojie ^c   Falk, Matthias M ^b   Jain, Himanshu ^c  

^a ICEMS   (Portugal)

^b LEHIGH UNIVERSITY   (United States)

^c Lehigh University   (United States)

^d Dow Corning SA Belgium   (Belgium)

^e UNIVERSITÉ CHEIKH ANTA DIOP   (Senegal)

Author keywords

[No Author keywords available]

Indexed keywords

BIOACTIVITY; BONE; ETHYLENE; GLASS; HYDROXYAPATITE; NANOPORES; PHASE SEPARATION; POLYETHYLENE OXIDES; PORE SIZE; SCANNING ELECTRON MICROSCOPY; SILICA; SOLVENTS;

HIGH-RESOLUTION SCANNING ELECTRON MICROSCOPIES; HYDROXYAPATITE LAYERS; IN-VITRO BIOACTIVITY; MERCURY INTRUSION POROSIMETRY; MODIFIED SOL-GEL PROCESS; PORE INTERCONNECTIVITY; SIMULATED BODY FLUIDS; SOL-GEL TRANSITIONS;

SOL-GEL PROCESS;

EID: 77952627307     PISSN: 08842914     EISSN: None     Source Type: Journal    
DOI: 10.1557/jmr.2009.0440     Document Type: Article

References (19)

1. J.R. Jones, L.M. Ehrenfried, and L.L. Hench: Optimizing bioactive glass scaffolds for bone tissue engineering. Biomaterials 27, 964 (2006).
2. L.L. Hench, R.J. Splinter, W.C. Allen, and T.K. Greenlee, Jr.: Bonding mechanisms at the interface of ceramic prosthetic materials. J. Biomed. Mater. Res. 2, 117 (1971).
3. M.M. Pereira and L.L. Hench: Mechanisms of hydroxyapatite formation on porous gel-silica substrates. J. Sol-Gel Sci. Technol. 7, 59 (1996).
4. T.M. Freyman, I.V. Yannas, and L.J. Gibson: Cellular materials as porous scaffolds for tissue engineering. Prog. Mater. Sci. 46, 273 (2001).
5. K. Nakanishi: Pore structure control of silica gels based on phase separation. J. Porous Mater. 4, 67 (1997).
6. R. Takahashi, S. Sato, T. Sodesawa, T. Goto, K. Matsutani, and N. Mikami: Bending strength of silica gel with bimodal pores: Effect of variation in mesopore structure. Mater. Res. Bull. 40, 1148 (2005).
7. P. Sepulveda, J.R. Jones, and L.L. Hench: Bioactive sol-gel foams for tissue repair. J. Biomed. Mater. Res. 59, 340 (2002).
8. J.R. Jones, O. Tsigkou, E.E. Coates, M.M. Stevens, J.M. Polak, and L.L. Hench: Extracellular-matrix formation and mineralization on a phosphate-free porous bioactive glass scaffold using primary human osteoblast (HOB) cells. Biomaterials 28, 1653 (2007).
9. H. Maekawa, J. Esquena, S. Bishop, C. Solans, and B.F. Chmelka: Meso/macroporous inorganic oxide monoliths from polymer foams. Adv. Mater. 15, 591 (2003).
10. W. Liang and C. Rüssel: Resorbable, porous glass scaffolds by a salt sintering process. J. Mater. Sci. 41, 3787 (2006).
11. H.S. Yun, S.E. Kim, and Y.T. Hyun: Fabrication of hierarchically porous bioactive glass ceramics. Key Eng. Mater. 361-363, 285 (2008).
12. C.M. Lofton, C.B. Milz, H. Huang, and W.M. Sigmund: Bicontinuous porosity in ceramics utilizing polymer spinodal phase separation. J. Eur. Ceram. Soc. 25, 883 (2005).
13. A.C. Marques, H. Jain, and R.M. Almeida: Sol-gel derived nano/ macroporous monolithic scaffolds. Phys. Chem. Glasses: Eur. J. Glass Sci. Technol. B 48, 65 (2007).
14. A.C. Marques, H. Jain, and R.M. Almeida: Nano/macroporous monolithic scaffolds prepared by the sol-gel method. J. Sol-Gel Sci. Technol. 51, 42 (2009).
15. T. Kokubo and H. Takadama: How useful is SBF in predicting in vivo bone bioactivity? Biomaterials 27, 2907 (2006).
16. R.M. Almeida and A.C. Marques: Characterization of sol-gel materials by infrared spectroscopy, in Handbook of Sol-Gel Science and Technology, edited by S. Sakka (Kluwer Academic Publishers, London, 2005).
17. M.M. Pereira, A.E. Clark, and L.L. Hench: Calcium phosphate formation on sol-gel-derived bioactive glasses in vitro. J. Biomed. Mater. Res. 28, 693 (1994).
18. N. Olmo, A.I. Martín, A.J. Salinas, J. Turnay, M. Vallet-Regi, and M.A. Lizarbe: Bioactive sol-gel glasses with and without a HCA layer as substrates for osteoblast cells adhesion and proliferation. Biomaterials 24, 3383 (2003).
19. J. Zhong and D.C. Greenspan: Processing and properties of sol-gel bioactive glasses. J. Biomed. Mater. Res. 53, 694 (2000).