-
1
-
-
0028224640
-
Effect of 2′,3′-didehydro-3′-deoxythymidine in an in vitro hollow-fiber pharmacodynamic model system correlates with results of dose-ranging clinical studies
-
Bilello, J. A., G. Bauer, M. N. Dudley, G. A. Cole, and G. L. Drusano. 1994. Effect of 2′,3′-didehydro-3′-deoxythymidine in an in vitro hollow-fiber pharmacodynamic model system correlates with results of dose-ranging clinical studies. Antimicrob. Agents Chemother. 38:1386-1391.
-
(1994)
Antimicrob. Agents Chemother.
, vol.38
, pp. 1386-1391
-
-
Bilello, J.A.1
Bauer, G.2
Dudley, M.N.3
Cole, G.A.4
Drusano, G.L.5
-
2
-
-
0021832112
-
In-vitro model for simultaneous simulation of the serum kinetics of two drugs with different half-lives
-
Blaser, J. 1985. In-vitro model for simultaneous simulation of the serum kinetics of two drugs with different half-lives. J. Antimicrob. Chemother. 15(Suppl. A):125-130.
-
(1985)
J. Antimicrob. Chemother.
, vol.15
, Issue.SUPPL. A
, pp. 125-130
-
-
Blaser, J.1
-
3
-
-
0021809096
-
Two compartment kinetic model with multiple artificial capillary units
-
Blaser, J., B. J. Stone, and S. H. Zinner. 1985. Two compartment kinetic model with multiple artificial capillary units. J. Antimicrob. Chemother. 15(Suppl. A):131-137.
-
(1985)
J. Antimicrob. Chemother.
, vol.15
, Issue.SUPPL. A
, pp. 131-137
-
-
Blaser, J.1
Stone, B.J.2
Zinner, S.H.3
-
5
-
-
33846182015
-
ADAPT II. A program for simulation, identification, and optimal experimental design
-
University of Southern California, Los Angeles, CA
-
D'Argenio, D. Z., and A. Schumitzky. 1997. ADAPT II. A program for simulation, identification, and optimal experimental design. User manual. Biomedical Simulations Resource, University of Southern California, Los Angeles, CA. http://bmsr.usc.edu/.
-
(1997)
User Manual
-
-
D'Argenio, D.Z.1
Schumitzky, A.2
-
6
-
-
77952602904
-
Impact of granulocytes on clearance of infection in a mouse thigh infection model: Pseudomonas aeruginosa is different from Staphylococcus aureus
-
abstr. A-992
-
Drusano, G. L., C. Fregeau, W. Liu, D. L. Brown, and A. Louie. 2008. Impact of granulocytes on clearance of infection in a mouse thigh infection model: Pseudomonas aeruginosa is different from Staphylococcus aureus, abstr. A-992. Abstr. 48th Annu. Intersci. Conf. Antimicrob. Agents Chemother. (ICAAC)-Infect. Dis. Soc. Am. (IDSA) 46th Annu. Meet. American Society for Microbiology and Infectious Diseases Society of America, Washington, DC.
-
(2008)
Abstr. 48th Annu. Intersci. Conf. Antimicrob. Agents Chemother. (ICAAC)-Infect. Dis. Soc. Am. (IDSA) 46th Annu. Meet. American Society for Microbiology and Infectious Diseases Society of America, Washington, DC
-
-
Drusano, G.L.1
Fregeau, C.2
Liu, W.3
Brown, D.L.4
Louie, A.5
-
7
-
-
67049107918
-
Differing effects of combination chemotherapy with meropenem and tobramycin on cell kill and suppression of resistance on wild-type Pseudomonas aeruginosa PAO1 and its isogenic MexAB efflux pump-overexpressed mutant
-
Drusano, G. L., W. Liu, C. Fregeau, R. Kulawy, and A. Louie. 2009. Differing effects of combination chemotherapy with meropenem and tobramycin on cell kill and suppression of resistance on wild-type Pseudomonas aeruginosa PAO1 and its isogenic MexAB efflux pump-overexpressed mutant. Antimicrob. Agents Chemother. 53:2266-2273.
-
(2009)
Antimicrob. Agents Chemother.
, vol.53
, pp. 2266-2273
-
-
Drusano, G.L.1
Liu, W.2
Fregeau, C.3
Kulawy, R.4
Louie, A.5
-
8
-
-
0028274211
-
Treatment of severe pneumonia in hospitalized patients: Results of a multicenter, randomized, double-blind trial comparing intravenous ciprofloxacin with imipenem-cilastatin
-
The Severe Pneumonia Study Group
-
Fink, M. P., D. R. Snydman, M. S. Niederman, K. V. Leeper, Jr., R. H. Johnson, S. O. Heard, R. G. Wunderink, J. W. Caldwell, J. J. Schentag, and G. A. Siami. 1994. Treatment of severe pneumonia in hospitalized patients: results of a multicenter, randomized, double-blind trial comparing intravenous ciprofloxacin with imipenem-cilastatin. The Severe Pneumonia Study Group. Antimicrob. Agents Chemother. 38:547-557.
-
(1994)
Antimicrob. Agents Chemother.
, vol.38
, pp. 547-557
-
-
Fink, M.P.1
Snydman, D.R.2
Niederman, M.S.3
Leeper Jr., K.V.4
Johnson, R.H.5
Heard, S.O.6
Wunderink, R.G.7
Caldwell, J.W.8
Schentag, J.J.9
Siami, G.A.10
-
9
-
-
6944234949
-
Selection of a moxifloxacin dose that suppresses Mycobacterium tuberculosis resistance using an in vitro pharmacodynamic infection model and mathematical modeling
-
Gumbo, T., A. Louie, M. R. Deziel, L. M. Parsons, M. Salfinger, and G. L. Drusano. 2004. Selection of a moxifloxacin dose that suppresses Mycobacterium tuberculosis resistance using an in vitro pharmacodynamic infection model and mathematical modeling. J. Infect. Dis. 190:1642-1651.
-
(2004)
J. Infect. Dis.
, vol.190
, pp. 1642-1651
-
-
Gumbo, T.1
Louie, A.2
Deziel, M.R.3
Parsons, L.M.4
Salfinger, M.5
Drusano, G.L.6
-
10
-
-
0042743965
-
Application of a mathematical model to prevent in-vivo amplification of antibiotic-resistant bacterial populations during therapy
-
Jumbe, N., A. Louie, R. Leary, W. Liu, M. R. Deziel, V. H. Tam, R. Bachhawat, C. Freeman, J. B. Kahn, K. Bush, M. N. Dudley, M. H. Miller, and G. L. Drusano. 2003. Application of a mathematical model to prevent in-vivo amplification of antibiotic-resistant bacterial populations during therapy. J. Clin. Invest. 112:275-285.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 275-285
-
-
Jumbe, N.1
Louie, A.2
Leary, R.3
Liu, W.4
Deziel, M.R.5
Tam, V.H.6
Bachhawat, R.7
Freeman, C.8
Kahn, J.B.9
Bush, K.10
Dudley, M.N.11
Miller, M.H.12
Drusano, G.L.13
-
11
-
-
33748670458
-
Crystal structures of a multidrug transporter reveal a functionally rotating mechanism
-
DOI 10.1038/nature05076, PII NATURE05076
-
Murakami, S., R. Nakashima, E. Yamashita, T. Matsumoto, and A. Yamaguchi. 2006. Crystal structures of a multidrug transporter reveal a functionally rotating mechanism. Nature 443:173-179. (Pubitemid 44387601)
-
(2006)
Nature
, vol.443
, Issue.7108
, pp. 173-179
-
-
Murakami, S.1
Nakashima, R.2
Yamashita, E.3
Matsumoto, T.4
Yamaguchi, A.5
-
12
-
-
0024417053
-
Evaluation of intravenous ciprofloxacin in patients with nosocomial lower respiratory tract infections: Impact of plasma concentration and clinical condition on bacterial eradication
-
Peloquin, C. A., T. J. Cumbo, D. E. Nix, M. F. Sands, and J. J. Schentag. 1989. Evaluation of intravenous ciprofloxacin in patients with nosocomial lower respiratory tract infections: impact of plasma concentration and clinical condition on bacterial eradication. Arch. Intern. Med. 149:2269-2273.
-
(1989)
Arch. Intern. Med.
, vol.149
, pp. 2269-2273
-
-
Peloquin, C.A.1
Cumbo, T.J.2
Nix, D.E.3
Sands, M.F.4
Schentag, J.J.5
-
13
-
-
0015221860
-
Empiric therapy with carbenicillin and gentamicin for febrile patients with cancer and granulocytopenia
-
Schimpff, S., W. Satterlee, V. M. Young, and A. Serpick. 1971. Empiric therapy with carbenicillin and gentamicin for febrile patients with cancer and granulocytopenia. N. Engl. J. Med. 284:1061-1065.
-
(1971)
N. Engl. J. Med.
, vol.284
, pp. 1061-1065
-
-
Schimpff, S.1
Satterlee, W.2
Young, V.M.3
Serpick, A.4
-
14
-
-
0343821919
-
The emergence of isoniazid-resistant cultures in patients with pulmonary tuberculosis during treatment with isoniazid alone or isoniazid plus PAS
-
Selkon, J. B., S. Devadatta, K. G. Kulkarni, D. A. Mitchison, A. S. Narayana, C. N. Nair, and K. Ramachandran. 1964. The emergence of isoniazid-resistant cultures in patients with pulmonary tuberculosis during treatment with isoniazid alone or isoniazid plus PAS. Bull. World Health Organ. 31:273-294.
-
(1964)
Bull. World Health Organ.
, vol.31
, pp. 273-294
-
-
Selkon, J.B.1
Devadatta, S.2
Kulkarni, K.G.3
Mitchison, D.A.4
Narayana, A.S.5
Nair, C.N.6
Ramachandran, K.7
-
15
-
-
33846572283
-
The relationship between quinolone exposures and resistance amplification is characterized by an inverted U: A new paradigm for optimizing pharmacodynamics to counterselect resistance
-
Tam, V. H., A. Louie, M. R. Deziel, W. Liu, and G. L. Drusano. 2007. The relationship between quinolone exposures and resistance amplification is characterized by an inverted U: a new paradigm for optimizing pharmacodynamics to counterselect resistance. Antimicrob. Agents Chemother. 51: 744-747.
-
(2007)
Antimicrob. Agents Chemother.
, vol.51
, pp. 744-747
-
-
Tam, V.H.1
Louie, A.2
Deziel, M.R.3
Liu, W.4
Drusano, G.L.5
-
16
-
-
34249870835
-
Drug exposure intensity and duration of therapy's impact on emergence of resistance of Staphylococcus aureus to a quinolone antimicrobial
-
Tam, V. H., A. Louie, T. R. Fritsche, M. Deziel, W. Liu, D. L. Brown, L. Deshpande, R. Leary, R. N. Jones, and G. L. Drusano. 2007. Drug exposure intensity and duration of therapy's impact on emergence of resistance of Staphylococcus aureus to a quinolone antimicrobial. J. Infect. Dis. 195:1818-1827.
-
(2007)
J. Infect. Dis.
, vol.195
, pp. 1818-1827
-
-
Tam, V.H.1
Louie, A.2
Fritsche, T.R.3
Deziel, M.4
Liu, W.5
Brown, D.L.6
Deshpande, L.7
Leary, R.8
Jones, R.N.9
Drusano, G.L.10
-
17
-
-
23844521731
-
Acute renal failure in critically ill patients: A multinational, multicenter study
-
Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators
-
Uchino, S., J. A. Kellum, R. Bellomo, G. S. Doig, H. Morimatsu, S. Morgera, M. Schetz, I. Tan, C. Bouman, E. Macedo, N. Gibney, A. Tolwany, and C. Ronco. 2005. Acute renal failure in critically ill patients: a multinational, multicenter study. Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators. JAMA 294:813-818.
-
(2005)
JAMA
, vol.294
, pp. 813-818
-
-
Uchino, S.1
Kellum, J.A.2
Bellomo, R.3
Doig, G.S.4
Morimatsu, H.5
Morgera, S.6
Schetz, M.7
Tan, I.8
Bouman, C.9
Macedo, E.10
Gibney, N.11
Tolwany, A.12
Ronco, C.13
-
18
-
-
77952621534
-
Levofloxacin versus imipenem/cilastatin followed by ciprofloxacin in the treatment of nosocomial pneumonia: A prospective, randomized, multicenter study
-
West, M., B. R. Boulanger, C. Fogarty, A. Tennenberg, B. Weisinger, M. Oross, S.-C. Wu, and J. B. Kahn. 2003. Levofloxacin versus imipenem/cilastatin followed by ciprofloxacin in the treatment of nosocomial pneumonia: a prospective, randomized, multicenter study. Clin. Ther. 25:486-506.
-
(2003)
Clin. Ther.
, vol.25
, pp. 486-506
-
-
West, M.1
Boulanger, B.R.2
Fogarty, C.3
Tennenberg, A.4
Weisinger, B.5
Oross, M.6
Wu, S.-C.7
Kahn, J.B.8
|