Single-Fraction High-Dose-Rate Brachytherapy and Hypofractionated External Beam Radiotherapy for Men With Intermediate-Risk Prostate Cancer: Analysis of Short- and Medium-Term Toxicity and Quality of Life

International Journal of Radiation Oncology Biology Physics

Volumn 77, Issue 3, 2010, Pages 811-817

  Morton, Gerard C ^a   Loblaw, D Andrew ^a   Sankreacha, Raxa ^b   Deabreu, Andrea ^a   Zhang, Liying ^a   Mamedov, Alexandre ^a   Cheung, Patrick ^a   Keller, Brian ^b   Danjoux, Cyril ^a   Szumacher, Ewa ^a   Thomas, Gillian ^a  

^a DEPARTMENT OF RADIATION ONCOLOGY   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

High dose rate brachytherapy; Hypofractionated radiotherapy; Prostate cancer

Indexed keywords

ADVERSE EVENTS; BIOCHEMICAL FAILURE; CLINICAL EXAMINATION; COMMON TERMINOLOGY CRITERIA; CONCENTRATION OF; ERECTILE DYSFUNCTION; EXPANDED PROSTATE CANCER INDEX COMPOSITES; EXTERNAL BEAM RADIATION THERAPY; EXTERNAL BEAM RADIOTHERAPY; GASTROINTESTINAL TOXICITIES; GENITOURINARY TOXICITIES; GLEASON SCORES; HEALTH-RELATED QUALITY OF LIVES; HIGH-DOSE-RATE BRACHYTHERAPY; INTERNATIONAL PROSTATE SYMPTOM SCORES; LOCALIZED PROSTATE CANCER; LOW TOXICITY; MEDIUM TERM; PROSTATE BIOPSY; PROSTATE CANCERS; PROSTATE SPECIFIC ANTIGEN; QUALITY OF LIFE; URINARY SYMPTOMS;

BIOPSY; DISEASE CONTROL; DISEASES; HEALTH RISKS; ONCOLOGY; RADIATION EFFECTS; TOXICITY;

RADIOTHERAPY;

PROSTATE SPECIFIC ANTIGEN;

ADULT; AGED; ARTICLE; BRACHYTHERAPY; CANCER RISK; CLINICAL EXAMINATION; CLINICAL TRIAL; COMMON TERMINOLOGY CRITERIA FOR ADVERSE EVENTS; ERECTILE DYSFUNCTION; EXPANDED PROSTATE CANCER INDEX COMPOSITE; EXTERNAL BEAM RADIOTHERAPY; FOLLOW UP; GASTROINTESTINAL TOXICITY; GLEASON SCORE; HUMAN; HUMAN TISSUE; INTERNATIONAL INDEX OF ERECTILE FUNCTION; INTERNATIONAL PROSTATE SYMPTOM SCORE; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PENIS ERECTION; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; PROSTATE BIOPSY; PROSTATE CANCER; QUALITY OF LIFE; RADIATION DOSE FRACTIONATION; RADIATION RESPONSE; SCORING SYSTEM; URINARY TRACT DISEASE; UROGENITAL TRACT DISEASE;

ACUTE DISEASE; AGED; AGED, 80 AND OVER; BRACHYTHERAPY; DOSE FRACTIONATION; ERECTILE DYSFUNCTION; GASTROINTESTINAL TRACT; HEALTH STATUS; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC NEOPLASMS; QUALITY OF LIFE; RADIOTHERAPY, CONFORMAL; REGRESSION ANALYSIS; URINATION DISORDERS;

EID: 77952573175     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2009.05.054     Document Type: Article

References (18)

1. Morton G.C. The emerging role of high-dose-rate brachytherapy for prostate cancer. Clin Oncol (R Coll Radiol) 17 4 (2005) 219-227
2. Hoskin P.J., Motohashi K., Bownes P., Bryant L., and Ostler P. High dose rate brachytherapy in combination with external beam radiotherapy in the radical treatment of prostate cancer: initial results of a randomised phase three trial. Radiother Oncol 84 2 (2007) 114-120
3. Kim Y., Hsu I.C., and Pouliot J. Measurement of craniocaudal catheter displacement between fractions in computed tomography-based high dose rate brachytherapy of prostate cancer. J Appl Clin Med Phys 8 4 (2007) 2415
4. Loblaw D.A., and Cheung P. External beam irradiation for localized prostate cancer: The promise of hypofractionation. Can J Urol 13 Suppl 1 (2006) 62-66
5. Ritter M. Rationale, conduct, and outcome using hypofractionated radiotherapy in prostate cancer. Semin Radiat Oncol 18 4 (2008) 249-256
6. Lessard E., and Pouliot J. Inverse planning anatomy-based dose optimization for HDR-brachytherapy of the prostate using fast simulated annealing algorithm and dedicated objective function. Med Phys 28 5 (2001) 773-779
7. Rosen R.C., Riley A., Wagner G., Osterloh I.H., Kirkpatrick J., and Mishra A. The international index of erectile function (IIEF): A multidimensional scale for assessment of erectile dysfunction. Urology 49 6 (1997) 822-830
8. Wei J.T., Dunn R.L., Litwin M.S., Sandler H.M., and Sanda M.G. Development and validation of the expanded prostate cancer index composite (EPIC) for comprehensive assessment of health-related quality of life in men with prostate cancer. Urology 56 6 (2000) 899-905
9. Keyes M., Miller S., Moravan V., Pickles T., McKenzie M., Pai H., et al. Predictive factors for acute and late urinary toxicity after permanent prostate brachytherapy: long-term outcome in 712 consecutive patients. Int J Radiat Oncol Biol Phys 73 4 (2009) 1023-1032
10. Keyes M., Schellenberg D., Moravan V., McKenzie M., Agranovich A., Pickles T., et al. Decline in urinary retention incidence in 805 patients after prostate brachytherapy: The effect of learning curve?. Int J Radiat Oncol Biol Phys 64 3 (2006) 825-834
11. Ferrer M., Suarez J.F., Guedea F., Fernandez P., Macias V., Marino A., et al. Health-related quality of life 2 years after treatment with radical prostatectomy, prostate brachytherapy, or external beam radiotherapy in patients with clinically localized prostate cancer. Int J Radiat Oncol Biol Phys 72 2 (2008) 421-432
12. Kupelian P.A., Reddy C.A., Klein E.A., and Willoughby T.R. Short-course intensity-modulated radiotherapy (70 GY at 2.5 GY per fraction) for localized prostate cancer: preliminary results on late toxicity and quality of life. Int J Radiat Oncol Biol Phys 51 4 (2001) 988-993
13. Ash D., Bottomley D., Al Qaisieh B., Carey B., Gould K., and Henry A. A prospective analysis of long-term quality of life after permanent I-125 brachytherapy for localised prostate cancer. Radiother Oncol 84 2 (2007) 135-139
14. Schroeck F.R., Krupski T.L., Sun L., Albala D.M., Price M.M., Polascik T.J., et al. Satisfaction and regret after open retropubic or robot-assisted laparoscopic radical prostatectomy. Eur Urol 54 4 (2008) 785-793
15. Pinkawa M., Fischedick K., Treusacher P., Asadpour B., Gagel B., Piroth M.D., et al. Dose-volume impact in high-dose-rate Iridium-192 brachytherapy as a boost to external beam radiotherapy for localized prostate cancer-A phase II study. Radiother Oncol 78 1 (2006) 41-46
16. Pinkawa M., Gagel B., Piroth M.D., Fischedick K., Asadpour B., Kehl M., et al. Erectile dysfunction after external beam radiotherapy for prostate cancer. Eur Urol (2008, March 24) Epub ahead of print.
17. Merrick G.S., Butler W.M., Wallner K.E., Galbreath R.W., and Lief J.H. Long-term urinary quality of life after permanent prostate brachytherapy. Int J Radiat Oncol Biol Phys 56 2 (2003) 454-461
18. Link R.E., Su L.M., Sullivan W., Bhayani S.B., and Pavlovich C.P. Health related quality of life before and after laparoscopic radical prostatectomy. J Urol 173 1 (2005) 175-179