β-Catenin regulates melanocyte dendricity through the modulation of PKCζ and PKCδ

Pigment Cell and Melanoma Research

Volumn 23, Issue 3, 2010, Pages 385-393

  Kim, Jin Hwa ^a   Sohn, Kyung Cheol ^b   Choi, Tae Young ^b   Kim, Mi Yoon ^b   Ando, Hideya ^c,d   Choi, Sun Ja ^e,f   Kim, Sooil ^b   Lee, Young Ho ^b   Lee, Jeung Hoon ^b   Kim, Chang Deok ^b   Yoon, Tae Jin ^a  

^a Gyeongsang National University School of Medicine   (South Korea)

^b Chungnam National University   (South Korea)

^c DOSHISHA UNIVERSITY   (Japan)

^d Kobe Skin Research Institute   (South Korea)

^e Daeduk University   (South Korea)

^f Chonbuk National University   (South Korea)

Author keywords

catenin; Dendrite; Normal human epidermal melanocytes; PKC ; PKC

Indexed keywords

BETA CATENIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN CDC42; PROTEIN KINASE C DELTA; PROTEIN KINASE C ZETA; RAC1 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN;

ADENOVIRUS; ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CELL STRUCTURE; CONTROLLED STUDY; DENDRITIC CELL; DOWN REGULATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MELANOCYTE; MELANOGENESIS; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SKIN PIGMENTATION; UPREGULATION;

BETA CATENIN; CYTOSKELETON; DENDRITES; EPIDERMIS; HUMANS; MALE; MELANOCYTES; MODELS, BIOLOGICAL; PIGMENTATION; PROTEIN KINASE C; PROTEIN KINASE C-DELTA; SIGNAL TRANSDUCTION;

ADENOVIRIDAE;

EID: 77952569763     PISSN: 17551471     EISSN: 1755148X     Source Type: Journal    
DOI: 10.1111/j.1755-148X.2010.00695.x     Document Type: Article

References (34)

1. Bagrodia, S., Derijard, B., Davis, R.J. Cerione, R.A. (1998). Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation. J. Biol. Chem. 270, 27995 27998.
2. Bahadoran, P., Aberdam, E., Mantoux, F., Buscà, R., Bille, K., Yalman, N., de Saint-Basile, G., Casaroli-Marano, R., Ortonne, J.P. Ballotti, R. (2001). Rab27a: a key to melanosome transport in human melanocytes. J. Cell Biol. 152, 843 850.
3. Carreira, S., Goodall, J., Denat, L., Rodriguez, M., Nuciforo, P., Hoek, K.S., Testori, A., Larue, L. Goding, C.R. (2006). Mitf regulation of Dia1 controls melanoma proliferation and invasiveness. Genes Dev. 20, 3426 3439.
4. Choi, T.Y., Kim, J.H., Ko, D.H., Kim, C.H., Hwang, J.S., Ahn, S., Kim, S.Y., Kim, C.D., Lee, J.H. Yoon, T.J. (2007). Zebrafish as a new model for phenotype-based screening of melanogenic regulatory compounds. Pigment Cell Res. 20, 120 127.
5. Delmas, V., Beermann, F., Martinozzi, S. et al. (2007). β-Catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N-Ras in melanoma development. Genes Dev. 21, 2923 2935.
6. Deroanne, C.F., Hamelryckx, D., Ho, T.T., Lambert, C.A., Catroux, P., Lapiere, C.M. Nusgens, B.V. (2005). Cdc42 downregulates MMP-1 expression by inhibiting the ERK1/2 pathway. J. Cell Sci. 118, 1173 1183.
7. Dorsky, R.I., Moon, R.T. Raible, D.W. (1998). Control of neural crest cell fate by the Wnt signalling pathway. Nature 396, 370 373.
8. Dorsky, R.I., Moon, R.T. Raible, D.W. (2000a). Environmental signals and cell fate specification in premigratory neural crest. Bioessays 22, 708 716.
9. Dorsky, R.I., Raible, D.W. Moon, R.T. (2000b). Direct regulation of nacre, a zebrafish MITF homolog required for pigment cell formation, by the Wnt pathway. Genes Dev. 14, 158 162.
10. Dunn, K.J., Williams, B.O., Li, Y. Pavan, W.J. (2000). Neural crest-directed gene transfer demonstrates Wnt1 role in melanocyte expansion and differentiation during mouse development. Proc. Natl. Acad. Sci. USA 97, 10050 10055.
11. Gat, U., DasGupta, R., Degenstein, L. Fuchs, E. (1998). De novo hair follicle morpho-genesis and hair tumors in mice expressing a truncated β-catenin in skin. Cell 95, 605 614.
12. Goodall, J., Martinozzi, S., Dexter, T.J., Champeval, D., Carreira, S., Larue, L. Goding, C.R. (2004). Brn-2 expression controls melanoma proliferation and is directly regulated by beta-catenin. Mol. Cell. Biol. 24, 2915 2922.
13. Hari, L., Brault, V., Kléber, M., Lee, H.Y., Ille, F., Leimeroth, R., Paratore, C., Suterm, U., Kemler, R. Sommer, L. (2002). Lineage-specific requirements of β-catenin in neural crest development. J. Cell Biol. 159, 867 880.
14. Hata, K., Hori, K. Takahashi, S. (2003). Role of p38 MAPK in lupeol-induced B16 2F2 mouse melanoma cell differentiation. J. Biochem. 134, 441 445.
15. Huang, C., Borchers, C.H., Schaller, M.D. Jacobson, K. (2004). Phosphorylation of paxillin by p38MAPK is involved in the neurite extension of PC-12 cells. J. Cell Biol. 164, 593 602.
16. Hume, A.N., Ushakov, D.S., Tarafder, A.K., Ferenczi, M.A. Seabra, M.C. (2007). Rab27a and MyoVa are the primary Mlph interactors regulating melanosome transport in melanocytes. J. Cell Sci. 120, 3111 3122.
17. Kohn, A.D. Moon, R.T. (2005). Wnt and calcium signaling: β-catenin-independent pathways. Cell Calcium 38, 439 446.
18. Kwon, Y.B., Lee, Y.S., Sohn, K.C., Piao, Y.J., Back, S.J., Seo, Y.J., Suhr, K.B., Park, J.K., Kim, C.D. Lee, J.H. (2007). Sphingosylphosphorylcholine- induced interleukin-6 production is mediated by protein kinase C and p42/44 extracellular signal-regulated kinase in human dermal fibroblasts. J. Dermatol. Sci. 46, 91 99.
19. Larue, L. Beermann, F. (2007). Cutaneous melanoma in genetically modified animals. Pigment Cell Res. 20, 485 497.
20. Larue, L. Delmas, V. (2006). The WNT/β-catenin pathway in melanoma. Front. Biosci. 11, 733 742.
21. Larue, L., Kumasaka, M. Goding, C.R. (2003). β-Catenin in the melanocyte lineage. Pigment Cell Res. 16, 312 317.
22. Li, C., Hu, Y., Sturm, G., Wick, G. Xu, Q. (2000). Ras/Rac-dependent activation of p38 mitogen-activated protein kinases in smooth muscle cells stimulated by cyclic strain stress. Arterioscler. Thromb. Vasc. Biol. 20, E1 E9.
23. Linseman, D.A. Loucks, F.A. (2008). Diverse roles of Rho family GTPases in neuronal development, survival, and death. Front. Biosci. 13, 657 676.
24. Minden, A., Lin, A., Claret, F.X., Abo, A. Karin, M. (1995). Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs. Cell 81, 1147 1157.
25. Morooka, T. Nishida, E. (1998). Requirement of p38 mitogen-activated protein kinase for neuronal differentiation in PC12 cells. J. Biol. Chem. 273, 24285 24288.
26. Schepsky, A., Bruser, K., Gunnarsson, G.J., Goodall, J., Hallsson, J.H., Goding, C.R., Steingrimsson, E. Hecht, A. (2006). The microphthalmia-associated transcription factor Mitf interacts with β-catenin to determine target gene expression. Mol. Cell. Biol. 26, 8914 8927.
27. Scott, G. (2002). Rac and rho: the story behind melanocyte dendrite formation. Pigment Cell Res. 15, 322 330.
28. Sohn, K.C., Shi, G., Jang, S. et al. (2009). Pitx2, a β-catenin-regulated transcription factor, regulates the differentiation of outer root sheath cells cultured in vitro. J. Dermatol. Sci. 54, 6 11.
29. Steingrimsson, E., Moore, K.J., Lamoreux, M.L. et al. (1994). Molecular basis of mouse microphthalmia (mi) mutations helps explain their developmental and phenotypic consequences. Nat. Genet. 8, 256 263.
30. Takeda, K., Yasumoto, K., Takada, R., Takada, S., Watanabe, K., Udono, T., Saito, H., Takahashi, K. Shibahara, S. (2000). Induction of melanocyte-specific microphthalmia-associated transcription factor by Wnt-3a. J. Biol. Chem. 275, 14013 14016.
31. Vasiliev, J.M. (2004). Cytoskeletal mechanisms responsible for invasive migration of neoplastic cells. Int. J. Dev. Biol. 48, 425 439.
32. Widlund, H.R., Horstmann, M.A., Price, E.R., Cui, J., Lessnick, S.L., Wu, M., He, X. Fisher, D.E. (2002). β-Catenin-induced melanoma growth requires the downstream target microphthalmia-associated transcription factor. J. Cell Biol. 158, 1079 1087.
33. 2-terminal truncated β-catenin on mouse intestinal epithelial homeostasis. J. Cell Biol. 141, 765 777.
34. Wu, X., Wang, F., Rao, K., Sellers, J.R. Hammer, J.A. III. (2002). Rab27a is an essential component of melanosome receptor for myosin Va. Mol. Biol. Cell 13, 1735 1749.