TGFβ1 induces Jagged1 expression in astrocytes via ALK5 and Smad3 and regulates the balance between oligodendrocyte progenitor proliferation and differentiation

GLIA

Volumn 58, Issue 8, 2010, Pages 964-974

  Zhang, Yueting ^a   Zhang, Jingya ^a   Navrazhina, Kristina ^a   Argaw, Azeb Tadesse ^a   Zameer, Andleeb ^a   Gurfein, Blake T ^a   Brosnan, Celia F ^b   John, Gareth R ^a,b  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Autoimmunity; CNS repair; Multiple sclerosis; Notch

Indexed keywords

ACTIN; ACTIVIN A; GLYCOGEN SYNTHASE KINASE 3; JAGGED1; MITOGEN ACTIVATED PROTEIN KINASE P38; NOTCH1 RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; SMAD2 PROTEIN; SMAD3 PROTEIN; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3; BETAIG H3 PROTEIN; BETAIG-H3 PROTEIN; CALCIUM BINDING PROTEIN; ENZYME INHIBITOR; MEMBRANE PROTEIN; PROTEIN SERINE THREONINE KINASE; SCLEROPROTEIN; SERRATE PROTEINS; SIGNAL PEPTIDE; TGF BETA TYPE I RECEPTOR; TGF-BETA TYPE I RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ARTICLE; ASTROCYTE; CELL PROLIFERATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN TISSUE; MULTIPLE SCLEROSIS; MYELINATION; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN INDUCTION; REGULATORY MECHANISM; REMYELINIZATION; SIGNAL TRANSDUCTION; ANALYSIS OF VARIANCE; ANIMAL; BRAIN CORTEX; CELL DIFFERENTIATION; CYTOLOGY; DRUG EFFECT; GENETIC TRANSFECTION; METABOLISM; METHODOLOGY; NEWBORN; PHYSIOLOGY; RAT; STEM CELL;

ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; CALCIUM-BINDING PROTEINS; CELL DIFFERENTIATION; CELL PROLIFERATION; CEREBRAL CORTEX; ENZYME INHIBITORS; EXTRACELLULAR MATRIX PROTEINS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; OLIGODENDROGLIA; PROTEIN-SERINE-THREONINE KINASES; RATS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RNA, SMALL INTERFERING; SMAD3 PROTEIN; STEM CELLS; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 77952559805     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.20978     Document Type: Article

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