Congenital abnormalities in the offspring of pregnant women with type 1, type 2 and gestational diabetes mellitus: A population-based case-control study

Congenital Anomalies

Volumn 50, Issue 2, 2010, Pages 115-121

  Bánhidy, Ferenc ^a   Ács, Nándor ^a   Puhó, Erzsébet H ^b   Czeizel, Andrew E ^b  

^a Semmelweis University   (Japan)

^b FOUNDATION FOR THE COMMUNITY CONTROL OF HEREDITARY DISEASES   (Hungary)

Author keywords

Congenital abnormality; Gestational diabetes mellitus; Maternal effect; Population based case control study; Pregnancy; Type 1; Type 2

Indexed keywords

ADULT; ANUS ATRESIA; ARTICLE; BIRTH DEFECT; CARDIOVASCULAR MALFORMATION; CAUDAL REGRESSION SYNDROME; CLEFT LIP PALATE; CLEFT PALATE; CLUBFOOT; CONGENITAL DISORDER; CONTROLLED STUDY; CRYPTORCHISM; DIAPHRAGM DISEASE; EAR MALFORMATION; ESOPHAGUS ATRESIA; ESOPHAGUS STENOSIS; FEMALE; FETUS MALFORMATION; GASTROSCHISIS; HUMAN; HUNGARY; HYPOSPADIAS; INSULIN DEPENDENT DIABETES MELLITUS; INTESTINE ATRESIA; INTESTINE STENOSIS; KIDNEY AGENESIS; KIDNEY DYSGENESIS; KIDNEY MALFORMATION; LIMB MALFORMATION; MAJOR CLINICAL STUDY; MUSCULOSKELETAL SYSTEM MALFORMATION; NEURAL TUBE DEFECT; NEWBORN DISEASE; NON INSULIN DEPENDENT DIABETES MELLITUS; POLYDACTYLY; POPULATION BASED CASE CONTROL STUDY; PREGNANCY DIABETES MELLITUS; PREGNANT WOMAN; PRENATAL CARE; PRIORITY JOURNAL; PROGENY; RECTUM STENOSIS; RISK ASSESSMENT; SYNDACTYLY; UMBILICAL HERNIA; URINARY TRACT MALFORMATION; ABNORMALITIES, DRUG-INDUCED; ADOLESCENT; CASE CONTROL STUDY; COMPLICATION; CONGENITAL ABNORMALITIES; INFANT; NEWBORN; PREGNANCY;

ABNORMALITIES, DRUG-INDUCED; ADOLESCENT; ADULT; CASE-CONTROL STUDIES; CONGENITAL ABNORMALITIES; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; DIABETES, GESTATIONAL; FEMALE; HUMANS; HUNGARY; INFANT; INFANT, NEWBORN; PREGNANCY;

EID: 77952557361     PISSN: 09143505     EISSN: 17414520     Source Type: Journal    
DOI: 10.1111/j.1741-4520.2010.00275.x     Document Type: Article

References (40)

1. Aberg A, Westbom L, Kallen B (2001) Congenital malformations among infants whose mothers had gestational diabetes or preexisting diabetes. Early Hum Develop 61 : 95 96.
2. Becerra JE, Khoury MJ, Cordero JF et al 1990) Diabetes mellitus during pregnancy and the risk for specific birth defects: A population-based case-control study. Pediatrics 85 : 1 9.
3. Ben-Haroush A, Yogev Y, Hod M (2004) Epidemiology of gestational diabetes mellitus and its association with type 2 diabetes. Diabet Med 21 : 103 113.
4. Czeizel AE (1996) Reduction of urinary tract and cardiovascular defects by periconceptional multivitamin supplementation. Am J Med Genet 62 : 179 183.
5. Czeizel AE (1997) The first 25 years of the Hungarian Congenital Abnormality Registry. Teratology 55 : 299 305.
6. Czeizel AE (1999) Ten years experience in periconceptional care. Eur J Obstet Gynecol Reprod Biol 84 : 43 49.
7. Czeizel AE, Dobo M, Vargha P (2004) Hungarian cohort-controlled trial of periconceptional multivitamin supplementation shows reduction in certain congenital abnormalities. Birth Defects Res (Part A) 70 : 853 861.
8. Czeizel AE, Dudas I (1992) Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. N Engl J Med 327 : 1832 1835.
9. Czeizel AE, Evans JA, Kodaj I, Lenz W (1994) Congenital Limb Deficiencies in Hungary. Genetic and Teratologic Epidemiological Studies. Akadémiai Kiadó, Budapest.
10. Czeizel AE, Intõdy ZS, Modell B (1993) What proportion of congenital abnormalities can be prevented? Br Med J 306 : 499 503.
11. Czeizel AE, Medveczi E (2003) No difference in the occurrence of multimalformed offspring after periconceptional multivitamin supplementation. Obstet Gynecol 102 : 1255 1261.
12. Czeizel AE, Petik D, Vargha P (2003) Validation studies of drug exposures in pregnant women. Pharmacoepid Drug Safety 12 : 409 416.
13. Czeizel AE, Puho HE, Ács N, Bánhidy F (2008) Use of specified critical periods of different congenital abnormalities instead of the first trimester concept. Birth Defects Res (Part A) 82 : 139 146.
14. Czeizel AE, Puhó E, Bánhidy F (2006) No association between periconceptional multivitamin supplementation and risk of multiple congenital abnormalities. A population-based case-control study. Am J Med Genet Part A 140A : 2469 2477.
15. Czeizel AE, Rockenbauer M, Siffel CS, Varga E (2001) Description and mission evaluation of the Hungarian Case-Control Surveillance of Congenital Abnormalities, 1980-1996. Teratology 63 : 176 185.
16. Czeizel AE, Timár L, Sárközi A (1999) Dose-dependent effect of folic acid on the prevention of orofacial clefts. Pediatrics 104 : e66.
17. Czeizel AE, Vargha P (2004) Periconceptional folic acid/multivitamin supplementation and twin pregnancy. Am J Obstet Gynecol 191 : 790 794.
18. Ferencz C, Rubin JN, NcCarter RJ, Clark EB (1990) Maternal diabetes and cardiovascular Malformations: predominance of double outlet right ventricle and truncus arteriosus. Teratology 41 : 319 326.
19. Greene MF (1999) Spontaneous abortions and major malformations in women with diabetes mellitus. Semin Reprod Endocrinol 17 : 127 136.
20. Kim C, Berger DK, Chamany S (2007) Recurrence of gestational diabetes mellitus: a systematic review. Diabetes Care 30 : 1314 1319.
21. Kritz-Siverstein D, Barrett-Connor E, Wingard DL (1989) The effect of parity on the later development of non-insulin-dependent diabetes mellitus. N Engl J Med 321 : 1214 1219.
22. Kucera J, Lenz W, Maier W (1965) Missbildungen der Beine und der kaudalen Wirbelsaule bei Kindern diabetischer Mütter. Dtsch Med Wochenschr 90 : 901 905.
23. Loffredo CA, Wilson PD, Ferencz C (2001) Maternal diabetes: An independent risk factors for major cardiovascular malformations with increased mortality of affected infants. Teratology 64 : 98 106.
24. Martinez-Frias NL, Bemejo E, Rodriguez-Pinilla E et al 1998) Epidemiological analysis of outcomes of pregnancy in gestational diabetic mothers. Am J Med Genet 78 : 140 145.
25. Meigs JB, Shader P, Sullivan LM et al 2008) Genotype score in addition to common risk factors for prediction of type 2 diabetes. N Engl J Med 359 : 2208 2219.
26. Milunsky A, Alpert E, Kitzmiller JL et al 1982) Prenatal diagnosis of neural tube defects. The importance of serum alfa-fetoprotein in diabetic pregnant women. Am J Obstet Gynecol 142 : 1030 1032.
27. Molsted-Pedersen L, Tygstrup I, Pedersen J (1964) Congenital malformations in newborn infants of diabetic women. Correlation with maternal diabetes vascular complications. Lancet 1 : 1124 1126.
28. Moore TR (2004) Diabetes in pregnancy. In : Creasy RK, Resnik R, Iams JS, eds. Maternal-Fetal Medicine, 5th edn. Saunders
29. MRC Vitamin Study Research Group (1991) Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. Lancet 338 : 131 137.
30. Nielsen GL, Norgard B, Puho E et al 2005) Risk of specific congenital abnormalities in offspring of women with diabetes. Diabet Med 22 : 693 696. (Pubitemid 40805888)
31. Passarge E, Lenz W (1966) Syndrome of caudal regression in infants of diabetic mothers: observations of further cases. Pediatrics 37 : 672 675.
32. Puho HE, Métneki J, Czeizel AE (2004) Maternal employment status and isolated orofacial clefts in Hungary. Cent Eur J Publ Health 13 : 144 148.
33. Reece EA, Leguizamón G, Wiznitzer A (2009) Gestational diabetes: the need for a common ground. Lancet 373 : 1789 1797.
34. Reece EA, Sivan E, Francis G et al 1998) Pregnancy outcomes among women with and without diabetic microvascular disease (White's classes B to FR) versus non-diabetic controls. Am J Perinatol 15 : 549 555.
35. Rusnak SL, Driscoll SG (1965) Congenital spinal anomalies in infants of diabetic mothers. Pediatrics 35 : 989 995.
36. Schaefer-Graf UM, Buchanan TA, Xiang A et al 2000) Patterns of congenital anomalies and relationship to initial maternal fasting glucose levels in pregnancies complicated by type 2 and gestational diabetes. Am J Obstet Gynecol 182 : 313 320.
37. Sheffield JS, Butler-Koster EL, Casey BM et al 2002) Maternal diabetes mellitus and infants malformations. Obstet Gynecol 100 : 925 930.
38. Weigensberg MJ, Goran MI (2009) Type 2 diabetes in children and adolescents. Lancet 373 : 1743 1744.
39. Weiss PAM, Coustan DR, eds (1988) Gestational Diabetes. Springer Verlag
40. White P (1937) Diabetes complicating pregnancy. Am J Obstet Gynecol 33 : 380 385.