Caffeine does not augment markers of muscle damage or leukocytosis following resistance exercise

International Journal of Sports Physiology and Performance

Volumn 5, Issue 1, 2010, Pages 18-26

  Machado, Marco ^a   Koch, Alexander J ^b   Willardson, Jeffrey M ^c   Dos Santos, Frederico C ^a   Curty, Victor M ^a   Pereira, Lucas N ^a  

^a Laboratory of Physiology and Biokinetic ^*  (Brazil)

^b TRUMAN STATE UNIVERSITY   (United States)

^c EASTERN ILLINOIS UNIVERSITY   (United States)

Author keywords

Exercise performance; Exercise physiology; Exercise training; Physical performance; Resistance training; Strength training

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BIOLOGICAL MARKER; CAFFEINE; CENTRAL STIMULANT AGENT; CREATINE KINASE; LACTATE DEHYDROGENASE;

ADOLESCENT; ARTICLE; BLOOD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; HUMAN; LEUKOCYTE; LEUKOCYTOSIS; LYMPHOCYTE COUNT; MALE; MONOCYTE; MUSCLE FATIGUE; NEUTROPHIL; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; RESISTANCE TRAINING; SKELETAL MUSCLE; SPORT; WEIGHT LIFTING;

ADOLESCENT; ALANINE TRANSAMINASE; ASPARTATE AMINOTRANSFERASES; BIOLOGICAL MARKERS; CAFFEINE; CENTRAL NERVOUS SYSTEM STIMULANTS; CREATINE KINASE; DOUBLE-BLIND METHOD; HUMANS; L-LACTATE DEHYDROGENASE; LEUKOCYTES; LEUKOCYTOSIS; LYMPHOCYTE COUNT; MALE; MONOCYTES; MUSCLE FATIGUE; MUSCLE, SKELETAL; NEUTROPHILS; RESISTANCE TRAINING; SOCCER; WEIGHT LIFTING;

EID: 77952555055     PISSN: 15550265     EISSN: None     Source Type: Journal    
DOI: 10.1123/ijspp.5.1.18     Document Type: Article

References (30)

1. Sökmen B, Armstrong LE, Kraemer WJ, Casa DJ, Dias JC, Judelson DA, Maresh CM. Caffeine use in sports: considerations for the athlete. J Strength Cond Res. 2008; 22: 978-986.
2. Armstrong LE, Casa DJ, Maresh CM, Ganio MS. Caffeine, fluid-electrolyte balance, temperature regulation, and exercise-heat tolerance. Exerc Sport Sci Rev. 2007; 35: 135-140.
3. Hoffman JR, Kang J, Ratamess NA, Jennings PF, Mangine GT, Faigenbaum AD. Effect of nutritionally enriched coffee consumption on aerobic and anaerobic exercise performance. J Strength Cond Res. 2007; 21: 456-459.
4. Stephenson DG. Caffeine - a valuable tool in excitation-contraction coupling research. J Physiol. 2008; 586: 695-696.
5. Schneiker KT, Bishop D, Dawson B, Hackett LP. Effects of Caffeine on Prolonged Intermittent-Sprint Ability in Team-Sport Athletes. Med Sci Sports Exerc. 2006; 38: 578-585. (Pubitemid 43364136)
6. James JE. Critical Review of Dietary Caffeine and Blood Pressure: A Relationship That Should Be Taken More Seriously. Psychosom Med. 2004; 66: 63-71.
7. Conway KJ, Orr R, Stannard SR. Effect of a divided caffeine dose on endurance cycling performance, postexercise urinary caffeine concentration, and plasma paraxanthine. J Appl Physiol. 2003; 94: 1557-1562. (Pubitemid 36348836)
8. Mclean C, Graham. TE. Effects of exercise and thermal stress on caffeine pharmacokinetics in men and eumenorrheic women. J Appl Physiol. 2002; 93: 1471-1478.
9. Dennehy CE, Tsourounis C, Horn AJ. Dietary supplement-related adverse events reported to the California Poison Control System. Am J Health Syst Pharm. 2005; 62: 1476-1482. (Pubitemid 41008861)
10. Kruk B, ChmuraJ, Krzeminski K, NazarK, PekkarienH, Kaciuba-Uscilko H. Influence of caffeine, cold and exercise on multiple choice reaction times. Psychopharmacology (Berl). 2001;157: 197-201. (Pubitemid 32802133)
11. Bulent S, Armstrong LE, Kraemer WJ, et al. Caffeine use in sports: Considerations for the athlete. J Strength Cond Res. 2008; 22: 978-986.
12. Walker GJ, Finlay O, Griffiths H, Sylvester J, Williams M, Bishop NC. Immunoendocrine Response to Cycling following Ingestion of Caffeine and Carbohydrate. Med Sci Sports Exerc. 2007; 39: 1554-1560. (Pubitemid 47360979)
13. Cox GR, Desbrow B, Montgomery PG, et al. Effect of different protocols of caffeine intake on metabolism and endurance performance. JAppl Physiol. 2002; 93: 990-999. (Pubitemid 34919672)
14. Kraemer WJ, Ratamess NA. Fundamentals of Resistance Exercise: progression and Exercise Prescription. Med Sci Sports Exerc. 2004; 36: 674-688.
15. Pedersen BK, Bruunsgaard H, Klokker M, Kappel M, MacLean DA, Nielsen HB, Rohde T, Ullum H, Zacho M. Exercise-induced immunomodulation-possible roles of neuroendocrine and metabolic factors. Int J Sports Med. 1997; 18(S1):s2-s7.
16. Tidball JG. Inflammation in Skeletal Muscle Regeneration. In: Schiaffino S, Partridge T, eds. Skeletal Muscle Repair and Regeneration. 1st ed. New York: Springer Science+Business Media, 2008: 243-268.
17. Liu JF, Chang WY, Chan KH, Tsai WY, Lin CL, Hsu MC. Blood Lipid Peroxides and Muscle Damage Increased following Intensive Resistance Exercise of Female Weightlifters. Ann N Y Acad Sci. 2005; 1042: 255-261.
18. Peake JM, Suzuki K, Wilson G, et al. Exercise-Induced Muscle Damage, Plasma Cytokines, and Markers of Neutrophil Activation. Med Sci Sports Exerc. 2005; 37: 737-745. (Pubitemid 40628277)
19. Magaudda L, Di Mauro D, Trimarchi F, Anastasi G. Effects of Physical Exercise on Skeletal Muscle Fiber: Ultrastructural and Molecular Aspects. Basic Appl Myol. 2004; 14: 17-21.
20. Bassini-Cameron A, Sweet E, Bottino A, Bittar C, Veiga C, Cameron LC. Effect of caffeine supplementation on haematological and biochemical variables in elite soccer players under physical stress conditions. Br J Sports Med. 2007; 41: 523-530. (Pubitemid 47216967)
21. Maridakis V, O'Connor PJ, Dudley GA, McCully KK. Caffeine attenuates delayed-onset muscle pain and force loss following eccentric exercise. J Pain. 2007; 8: 237-243. (Pubitemid 46366854)
22. Graham TE. Caffeine and exercise: metabolism, endurance and performance. Sports Med. 2001; 31: 785-807. (Pubitemid 32846190)
23. Bishop NC, Fitzgerald C, Porter PJ, Scanlon GA, Smith AC. Effect of caffeine ingestion on lymphocyte counts and subset activation in vivo following strenuous cycling. Eur J Appl Physiol. 2005; 93: 606-613. (Pubitemid 40443778)
24. Mayhew DL, Thyfault JP, Koch AJ. Rest interval length affects leukocyte levels during heavy resistance exercise. J Strength Cond Res. 2005; 19: 16-22.
25. Brancaccio P, Maffulli N, Limongelli FM. Creatine kinase monitoring in sport medicine. Br Med Bull. 2007; 81-82: 209-230. (Pubitemid 351194486)
26. Mougios V. Reference intervals for serum creatine kinase in athletes. Br J Sports Med. 2007; 41: 674-678. (Pubitemid 47518442)
27. Totsuka M, Nakaji S, Suzuki K, Sugawara K, Sato K. Break point of serum creatine kinase release after endurance exercise. J Appl Physiol. 2002; 93:1280-1286.
28. Pettersson J, Hindorf U, Persson P, et al. Muscular exercise can cause highly pathological liver function tests in healthy men. Br J Clin Pharmacol. 2008;65:253-259. (Pubitemid 351171267)
29. Chevion S, Moran DS, Heled Y, et al. Plasma antioxidant status and cell injury after severe physical exercise. Proc Natl Acad Sci USA. 2003; 100:5119-5123. (Pubitemid 36542668)
30. Tunnicliffe JM, Erdman KA, Reimer RA, Lun V, Shearer J. Consumption of dietary caffeine and coffee in physically active populations: physiological interactions. Appl PhysiolNutrMetab. 2008;33:1301-1310.