Thermodynamics of RTA3 peptide binding to membranes and consequences for antimicrobial activity

Biochimica et Biophysica Acta - Biomembranes

Volumn 1798, Issue 6, 2010, Pages 1254-1262

  Hawrani, Ayman ^a,b   Howe, Robin A ^c   Walsh, Timothy R ^b   Dempsey, Christopher E ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c UNIVERSITY HOSPITAL OF WALES   (United Kingdom)

Author keywords

Amphipathic peptide; Commensal organism; Cysteine; Free energy; Interfacial binding; Phospholipid bilayer

Indexed keywords

COLISTIN; POLYPEPTIDE ANTIBIOTIC AGENT; RTA3 PROTEIN; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO ACID SEQUENCE; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL OUTER MEMBRANE; BACTERICIDAL ACTIVITY; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; ESCHERICHIA COLI; LIPID VESICLE; MEMBRANE BINDING; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; SURFACE CHARGE; THERMODYNAMICS;

ANTI-INFECTIVE AGENTS; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; ESCHERICHIA COLI; PEPTIDES; PROTEIN BINDING; PSEUDOMONAS AERUGINOSA; STATIC ELECTRICITY;

ESCHERICHIA COLI; MAMMALIA; NEGIBACTERIA;

EID: 77952554008     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamem.2010.03.017     Document Type: Article

References (32)

1. Hawrani A., Howe R.A., Walsh T.R., Dempsey C.E. Origin of low mammalian cell toxicity in a class of highly active antimicrobial amphipathic peptides. J. Biol. Chem. 2008, 283:18636-18645.
2. Hancock R.E.W., Lehrer R. Cationic peptides: a new source of antibiotics. Trend. Biotechnol. 1998, 16:82-88.
3. Zasloff M. Antimicrobial peptides of multicellular organisms. Nature 2002, 415:389-395.
4. Zhang L.J., Falla T.J. Cationic antimicrobial peptides-an update. Exp. Opin. Invest. Drugs 2004, 13:97-106.
5. Jenssen H., Hamill P., Hancock R.E.W. Peptide antimicrobial agents. Clin. Microbiol. Rev. 2006, 19:491-511.
6. Pereira H.A. Novel therapies based on cationic antimicrobial peptides. Curr. Pharm. Biotech. 2006, 7:229-234.
7. Matsuzaki K. Control of cell selectivity of antimicrobial peptides. Biochim. Biophys. Acta 2009, 1788:1687-1692.
8. Vaara M. New approaches in peptide antibiotics. Curr. Opin. Pharmacol. 2009, 9:571-576.
9. Hornef M.W., Putsep K., Karlsson J., Refai E., Andersson M. Increased diversity of intestinal antimicrobial peptides by covalent dimer formation. Nat. Immunol. 2004, 5:836-843.
10. Batista C.V.F., Scaloni A., Rigden D.J., et al. A novel heterodimeric antimicrobial peptide from the tree-frog Phyllomedusa distincta. FEBS Lett. 2001, 494:85-89.
11. Boman H.G. Peptide antibiotics and their role in innate immunity. Annu. Rev. Immunol. 1995, 13:61-92.
12. Lee W.H., Zhang H., Zhang Y.X., Jin Y., Lai R., Zhang Y. Maximin 9, a novel free thiol containing antimicrobial peptide with antimycoplasma activity from frog Bombina maxima. FEBS Lett. 2005, 579:4443-4448.
13. Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically, Approved Standard - Sixth Edition. M7-A6 2003, Clinical and Laboratory Standards Institute (formerly NCCLS), Clinical and Laboratory Standards Institute, Wayne, PA.
14. Ladokhin A.S., Jayasinghe S., White S.H. How to measure and analyze tryptophan fluorescence in membranes properly, and why bother?. Anal. Biochem. 2000, 285:235-245.
15. Wall J., Golding C.A., van Veen M., O'Shea P. The use of fluoresceinphosphatidylethanolamine (FPE) as a real-time probe for peptide membrane interactions. Mol. Membr. Biol. 1995, 12:183-192.
16. Lehrer R.I., Barton A., Ganz T. Concurrent assessment of inner and outer-membrane permeabilization and bacteriolysis in Escherichia-coli by multiple wavelength spectrophotometry. J. Immunol. Met. 1988, 108:153-158.
17. Takei J., Remenyi A., Clarke A.R., Dempsey C.E. Self-association of disulphide-dimerised melittin analogues. Biochem. 1998, 37:5699-5708.
18. Dempsey C.E., Ueno S., Avison M.B. Enhanced membrane permeabilization and antibacterial activity of a disulfide-dimerized magainin analogue. Biochem. 2003, 42:402-409.
19. Fernandez-Vidall M., Jayasinghe S., Ladokhin A.S., White S.H. Folding amphipathic helices into membranes: amphiphilicity trumps hydrophobicity. J. Mol. Biol. 2007, 370:459-470.
20. Vaara M. Agents that increase the permeability of the outer membrane. Microbiol. Rev. 1992, 56:395-411.
21. Wu M.H., Maier E., Benz R., Hancock R.E.W. Mechanism of interaction of different classes of cationic antimicrobial peptides with planar bilayers and with the cytoplasmic membrane of Escherichia coli. Biochem. 1999, 38:7235-7242.
22. Wimley W.C., White S.H. Experimentally determined hydrophobicity scale for proteins at membrane interfaces. Nat. Struct. Biol. 1996, 3:842-848.
23. Wolfenden R. Experimental measures of amino acid hydrophobicity and the topology of transmembrane and globular proteins. J. Gen. Physiol. 2007, 129:357-362.
24. Hessa T., Kim H., Bihlmaier K., Lundin C., Boekel J., Andersson H., Nilsson I., White S.H., von Heijne G. Recognition of transmembrane helices by the endoplasmic reticulum translocon. Nature 2005, 433:377-381.
25. Hristova K., Dempsey C.E., White S.H. Structure, location, and membrane perturbations of melittin at the membrane interface. Biophys. J. 2001, 80:801-811.
26. Takei J., Remenyi A., Dempsey C.E. Generalized bilayer perturbation from peptide helix dimerisation at membrane surfaces: vesicle lysis induced by disulphide-dimerised melittin analogues. FEBS Lett. 1999, 442:11-14.
27. Brogden K.A. Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria?. Nat. Rev. Microbiol. 2005, 3:238-250.
28. Kwa A., Kosiakou S.K., Tam V.H., Falagas M.E. Polymyxin B: similarities to and differences from colistin (polymyxin E). Expert Rev. Anti-Infect. Ther. 2007, 5:811-821.
29. Pag U., Oedenkoven M., Sass V., Shai Y., Shamova O., Antcheva N., Tossi A., Sahl H.G. Analysis of in vitro activities and modes of action of synthetic antimicrobial peptides derived from an alpha-helical 'sequence template'. J. Antimicrob. Chemother. 2008, 61:341-352.
30. Takeshima K., Chikushi A., Lee K.-K., Yonehara S., Matsuzaki K. Translocation of analogues of the antimicrobial peptides magainin and buforin across human cell membranes. J. Biol. Chem. 2003, 278:1310-1315.
31. Nicolas P. Multifunctional host defense peptides: intracellular-targeting antimicrobial peptides. FEBS J. 2009, 276:6483-6496.
32. MacCallum J.L., Bennett W.F.D., Tieleman D.P. Distribution of amino acids in a lipid bilayer from computer simulations. Biophys. J. 2008, 94:3393-3404.