Ketamine impairs recognition memory consolidation and prevents learning-induced increase in hippocampal brain-derived neurotrophic factor levels

Neuroscience

Volumn 167, Issue 4, 2010, Pages 969-973

  Goulart, B K ^a,b,c   de Lima, M N M ^b,d   de Farias, C B ^a,b,c   Reolon, G K ^a,b,c   Almeida, V R ^a,b,c   Quevedo, J ^b,e   Kapczinski, F ^b,c   Schroder N ^b,f   Roesler, R ^a,b,c  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b National Institute for Translational Medicine INCT TM   (Brazil)

^c HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

^d NeuroAssay Ltd   (Brazil)

^e UNIVERSITY OF SOUTHERN SANTA CATARINA   (Brazil)

^f PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Brain derived neurotrophic factor; Ketamine; Memory consolidation; NMDA receptor; Novel object recognition

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; KETAMINE; SODIUM CHLORIDE;

AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; DRUG DOSE COMPARISON; EXPLORATORY BEHAVIOR; HIPPOCAMPUS; LEARNING; LONG TERM MEMORY; MALE; MEMORY CONSOLIDATION; MEMORY DISORDER; NONHUMAN; PRIORITY JOURNAL; RAT; RECOGNITION; SIGNAL TRANSDUCTION; TASK PERFORMANCE; TRAINING;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; HIPPOCAMPUS; KETAMINE; LEARNING; MALE; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; RECOGNITION (PSYCHOLOGY); TIME FACTORS;

EID: 77952553529     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2010.03.032     Document Type: Article

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