Influence of body mass index on complications and oncologic outcomes following hepatectomy for malignancy

Journal of Gastrointestinal Surgery

Volumn 14, Issue 5, 2010, Pages 849-857

  Mathur, Amit K ^a   Ghaferi, Amir A ^a   Sell, Kristen ^a   Sonnenday, Christopher J ^a   Englesbe, Michael J ^a   Welling, Theodore H ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Body mass index; Hepatectomy; Hepatic malignancy; Recurrence; Survival

Indexed keywords

AGE; AGED; ARTICLE; BODY MASS; COHORT ANALYSIS; COMPARATIVE STUDY; CONFIDENCE INTERVAL; DISEASE FREE SURVIVAL; FEMALE; FOLLOW UP; HUMAN; KAPLAN MEIER METHOD; LIVER RESECTION; LIVER TUMOR; MALE; METHODOLOGY; MIDDLE AGED; MORTALITY; OBESITY; PATHOLOGY; POSTOPERATIVE COMPLICATION; PROBABILITY; PROPORTIONAL HAZARDS MODEL; REFERENCE VALUE; RETROSPECTIVE STUDY; RISK; RISK ASSESSMENT; SEX DIFFERENCE; SURVIVAL; TUMOR RECURRENCE;

AGE FACTORS; AGED; BODY MASS INDEX; COHORT STUDIES; CONFIDENCE INTERVALS; DISEASE-FREE SURVIVAL; FEMALE; FOLLOW-UP STUDIES; HEPATECTOMY; HUMANS; KAPLAN-MEIERS ESTIMATE; LIVER NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; OBESITY; ODDS RATIO; POSTOPERATIVE COMPLICATIONS; PROBABILITY; PROPORTIONAL HAZARDS MODELS; REFERENCE VALUES; RETROSPECTIVE STUDIES; RISK ASSESSMENT; SEX FACTORS; SURVIVAL ANALYSIS;

EID: 77952550573     PISSN: 1091255X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11605-010-1163-5     Document Type: Article

References (32)

1. Ogden CL, Yanovski SZ, Carroll MD, Flegal KM. The epidemiology of obesity. Gastroenterology 2007; 132(6): 2087-2102.
2. Pitt HA. Hepato-pancreato-biliary fat: the good, the bad and the ugly. HPB (Oxford) 2007; 9(2): 92-97.
3. Renehan AG, Roberts DL, Dive C. Obesity and cancer: pathophysiological and biological mechanisms. Arch Physiol Biochem 2008; 114(1): 71-83.
4. Renehan AG, Tyson M, Egger M, Heller RF, Zwahlen M. Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies. Lancet 2008; 371(9612): 569-578.
5. Gedaly R, McHugh PP, Johnston TD, Jeon H, Ranjan D, Davenport DL. Obesity, diabetes, and smoking are important determinants of resource utilization in liver resection: a multicenter analysis of 1029 patients. Ann Surg 2009; 249(3): 414-419.
6. Benns M, Woodall C, Scoggins C, McMasters K, Martin R. The Impact of Obesity on Outcomes Following Pancreatectomy for Malignancy. Ann Surg Oncol 2009; 16(9): 2565-2569.
7. Utsunomiya T, Okamoto M, Kameyama T, Matsuyama A, Yamamoto M, Fujiwara M et al. Impact of obesity on the surgical outcome following repeat hepatic resection in Japanese patients with recurrent hepatocellular carcinoma. World J Gastroenterol 2008; 14(10): 1553-1558.
8. Mullen JT, Davenport DL, Hutter MM, Hosokawa PW, Henderson WG, Khuri SF et al. Impact of body mass index on perioperative outcomes in patients undergoing major intra-abdominal cancer surgery. Ann Surg Oncol 2008; 15(8): 2164-2172.
9. Ryan CK, Johnson LA, Germin BI, Marcos A. One hundred consecutive hepatic biopsies in the workup of living donors for right lobe liver transplantation. Liver Transpl 2002; 8(12): 1114-1122.
10. Kooby DA, Fong Y, Suriawinata A, Gonen M, Allen PJ, Klimstra DS et al. Impact of steatosis on perioperative outcome following hepatic resection. J Gastrointest Surg 2003; 7(8): 1034-1044.
11. Mathur A, Zyromski NJ, Pitt HA, Al-Azzawi H, Walker JJ, Saxena R et al. Pancreatic steatosis promotes dissemination and lethality of pancreatic cancer. J Am Coll Surg 2009; 208(5): 989-994; discussion 994-986.
12. Fleming JB, Gonzalez RJ, Petzel MQ, Lin E, Morris JS, Gomez H et al. Influence of obesity on cancer-related outcomes after pancreatectomy to treat pancreatic adenocarcinoma. Arch Surg 2009; 144(3): 216-221.
13. Larsson SC, Wolk A. Overweight, obesity and risk of liver cancer: a meta-analysis of cohort studies. Br J Cancer 2007; 97(7): 1005-1008.
14. Larsson SC, Wolk A. Obesity and the risk of gallbladder cancer: a meta-analysis. Br J Cancer 2007; 96(9): 1457-1461.
15. House MG, Fong Y, Arnaoutakis DJ, Sharma R, Winston CB, Protic M et al. Preoperative predictors for complications after pancreaticoduodenectomy: impact of BMI and body fat distribution. J Gastrointest Surg 2008; 12(2): 270-278.
16. Behrns KE, Tsiotos GG, DeSouza NF, Krishna MK, Ludwig J, Nagorney DM. Hepatic steatosis as a potential risk factor for major hepatic resection. J Gastrointest Surg 1998; 2(3): 292-298.
17. Schrader AJ, Rustemeier J, Rustemeier JC, Timmesfeld N, Varga Z, Hegele A et al. Overweight is associated with improved cancer-specific survival in patients with organ-confined renal cell carcinoma. J Cancer Res Clin Oncol 2009.
18. Haferkamp A, Pritsch M, Bedke J, Wagener N, Pfitzenmaier J, Buse S et al. The influence of body mass index on the long-term survival of patients with renal cell carcinoma after tumour nephrectomy. BJU Int 2008; 101(10): 1243-1246.
19. Ogino S, Nosho K, Baba Y, Kure S, Shima K, Irahara N et al. A Cohort Study of STMN1 Expression in Colorectal Cancer: Body Mass Index and Prognosis. Am J Gastroenterol 2009.
20. Ogino S, Shima K, Nosho K, Irahara N, Baba Y, Wolpin BM et al. A cohort study of p27 localization in colon cancer, body mass index, and patient survival. Cancer Epidemiol Biomarkers Prev 2009; 18(6): 1849-1858.
21. Meyerhardt JA, Niedzwiecki D, Hollis D, Saltz LB, Mayer RJ, Nelson H et al. Impact of body mass index and weight change after treatment on cancer recurrence and survival in patients with stage III colon cancer: findings from Cancer and Leukemia Group B 89803. J Clin Oncol 2008; 26(25): 4109-4115.
22. Meyerhardt JA, Tepper JE, Niedzwiecki D, Hollis DR, McCollum AD, Brady D et al. Impact of body mass index on outcomes and treatment-related toxicity in patients with stage II and III rectal cancer: findings from Intergroup Trial 0114. J Clin Oncol 2004; 22(4): 648-657.
23. Meyerhardt JA, Catalano PJ, Haller DG, Mayer RJ, Benson AB, 3rd, Macdonald JS et al. Influence of body mass index on outcomes and treatment-related toxicity in patients with colon carcinoma. Cancer 2003; 98(3): 484-495.
24. Dignam JJ, Polite BN, Yothers G, Raich P, Colangelo L, O'Connell MJ et al. Body mass index and outcomes in patients who receive adjuvant chemotherapy for colon cancer. J Natl Cancer Inst 2006; 98(22): 1647-1654.
25. Miyake K, Hayakawa K, Nishino M, Morimoto T, Mukaihara S. Effects of oral 5-fluorouracil drugs on hepatic fat content in patients with colon cancer. Acad Radiol 2005; 12(6): 722-727.
26. He S, Atkinson C, Evans Z, Ellett JD, Southwood M, Elvington A et al. A role for complement in the enhanced susceptibility of steatotic livers to ischemia and reperfusion injury. J Immunol 2009; 183(7): 4764-4772.
27. He S, Atkinson C, Qiao F, Cianflone K, Chen X, Tomlinson S. A complement-dependent balance between hepatic ischemia/reperfusion injury and liver regeneration in mice. J Clin Invest 2009; 119(8): 2304-2316.
28. Gao F, Xu X, Ling Q, Wu J, Zhou L, Xie HY et al. Efficacy and safety of moderately steatotic donor liver in transplantation. Hepatobiliary Pancreat Dis Int 2009; 8(1): 29-33.
29. Gomez D, Malik HZ, Bonney GK, Wong V, Toogood GJ, Lodge JP et al. Steatosis predicts postoperative morbidity following hepatic resection for colorectal metastasis. Br J Surg 2007; 94(11): 1395-1402.
30. Vetelainen R, Bennink RJ, van Vliet AK, van Gulik TM. Mild steatosis impairs functional recovery after liver resection in an experimental model. Br J Surg 2007; 94(8): 1002-1008.
31. Aloia T, Sebagh M, Plasse M, Karam V, Levi F, Giacchetti S et al. Liver histology and surgical outcomes after preoperative chemotherapy with fluorouracil plus oxaliplatin in colorectal cancer liver metastases. J Clin Oncol 2006; 24(31): 4983-4990.
32. El-Badry AM, Breitenstein S, Jochum W, Washington K, Paradis V, Rubbia-Brandt L et al. Assessment of Hepatic Steatosis by Expert Pathologists: The End of a Gold Standard. Ann Surg 2009; 250(5); 691-697.