Enhanced spinal excitation from ankle flexors to knee extensors during walking in stroke patients

Clinical Neurophysiology

Volumn 121, Issue 6, 2010, Pages 930-938

  Achache, V ^a,b   Mazevet, D ^a,c   Iglesias, C ^a   Lackmy, A ^a   Nielsen, J B ^d   Katz, R ^a,c   Marchand Pauvert, V ^a  

^a SORBONNE UNIVERSITÉ   (France)

^b Hôpital National Saint Maurice   (France)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Group II; Human; Locomotion; Spinal reflex; Stroke

Indexed keywords

ADAPTATION; ADULT; AGED; ANKLE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ELECTROMYOGRAM; ELECTROSTIMULATION; EXTENSOR MUSCLE; FEMALE; FLEXOR MUSCLE; GAIT DISORDER; HUMAN; JOINT STABILITY; KNEE; LATENT PERIOD; MALE; MOTONEURON; MUSCLE EXCITATION; PARESIS; PERONEUS NERVE; PRIORITY JOURNAL; QUADRICEPS FEMORIS MUSCLE; REFLEX; SPINAL CORD; STANDING; STROKE PATIENT; VASTUS LATERALIS MUSCLE; WALKING; WALKING SPEED;

ADULT; AGED; ANALYSIS OF VARIANCE; ANKLE; ELECTRIC STIMULATION; ELECTROMYOGRAPHY; FEMALE; GAIT; HUMANS; KNEE; MALE; MIDDLE AGED; MOVEMENT; MUSCLE, SKELETAL; PERONEAL NERVE; RECOVERY OF FUNCTION; SPINAL CORD; STROKE; WALKING;

EID: 77952543197     PISSN: 13882457     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinph.2009.12.037     Document Type: Article

References (41)

1. Brandstater M.E., de Bruin H., Gowland C., and Clark B.M. Hemiplegic gait: analysis of temporal variables. Arch Phys Med Rehabil 64 (1983) 583-587
2. Burridge J.H., Wood D.E., Taylor P.N., and McLellan D.L. Indices to describe different muscle activation patterns, identified during treadmill walking, in people with spastic drop-foot. Med Eng Phys 23 (2001) 427-434
3. Chaix Y., Marque P., Meunier S., Pierrot-Deseilligny E., and Simonetta-Moreau M. Further evidence for non-monosynaptic group I excitation of motoneurones in the human lower limb. Exp Brain Res 115 (1997) 35-46
4. Chen G., Patten C., Kothari D.H., and Zajac F.E. Gait differences between individuals with post-stroke hemiparesis and non-disabled controls at matched speeds. Gait Posture 22 (2005) 51-56
5. Choi J.T., and Bastian A.J. Adaptation reveals independent control networks for human walking. Nat Neurosci 10 (2007) 1055-1062
6. Crone C., Johnsen L.L., Biering-Sørensen F., and Nielsen J.B. Appearance of reciprocal facilitation of ankle extensors from ankle flexors in patients with stroke or spinal cord injury. Brain 126 (2003) 495-507
7. Den Otter A.R., Geurts A.C., Mulder T., and Duysens J. Abnormalities in the temporal patterning of lower extremity muscle activity in hemiparetic gait. Gait Posture 25 (2007) 342-352
8. Den Otter A.R., Geurts A.C., Mulder T., and Duysens J. Gait recovery is not associated with changes in the temporal patterning of muscle activity during treadmill walking in patients with post-stroke hemiparesis. Clin Neurophysiol 117 (2006) 4-15
9. Den Otter A.R., Geurts A.C., Mulder T., and Duysens J. Speed related changes in muscle activity from normal to very slow walking speeds. Gait Posture 19 (2004) 270-278
10. Dietz V., and Sinkjaer T. Spastic movement disorder: impaired reflex function and altered muscle mechanics. Lancet Neurol 6 (2007) 725-733
11. Dobkin B.H. Training and exercise to drive poststroke recovery. Nat Clin Pract Neurol 4 (2008) 76-85
12. Farmer S.F., Swash M., Ingram D.A., and Stephens J.A. Changes in motor unit synchronization following central nervous lesions in man. J Physiol 463 (1993) 83-105
13. Hultborn H., Brownstone R.B., Toth T.I., and Gossard J.P. Key mechanisms for setting the input-output gain across the motoneuron pool. Prog Brain Res 143 (2004) 77-95
14. Iglesias C., Nielsen J.B., and Marchand-Pauvert V. Corticospinal inhibition of transmission in propriospinal-like neurones during human walking. Eur J Neurosci 28 (2008) 1351-1361
15. Iglesias C., Nielsen J.B., and Marchand-Pauvert V. Speed-related spinal excitation from ankle dorsiflexors to knee extensors during human walking. Exp Brain Res 188 (2008) 101-110
16. Jahn K., Deutschländer A., Stephan T., Kalla R., Hüfner K., Wagner J., et al. Supraspinal locomotor control in quadrupeds and humans. Prog Brain Res 171 (2008) 353-362
17. Jankowska E. Interneuronal relay in spinal pathways from proprioceptors. Prog Neurobiol 38 (1992) 335-378
18. Lamontagne A., Stephenson J.L., and Fung J. Physiological evaluation of gait disturbances post stroke. Clin Neurophysiol 118 (2007) 717-729
19. Marchand-Pauvert V., Nicolas G., Marque P., Iglesias C., and Pierrot-Deseilligny E. Increase in group II excitation from ankle muscles to thigh motoneurones during human standing. J Physiol 566 (2005) 257-271
20. Marchand-Pauvert V., and Nielsen J.B. Modulation of non-monosynaptic excitation from ankle dorsiflexor afferents to quadriceps motoneurones during human walking. J Physiol 538 (2002) 647-657
21. Marque P., Nicolas G., Simonetta-Moreau M., Pierrot-Deseilligny E., and Marchand-Pauvert V. Group II excitations from plantar foot muscles to human leg and thigh motoneurones. Exp Brain Res 161 (2005) 486-501
22. Marque P., Pierrot-Deseilligny E., and Simonetta-Moreau M. Evidence for excitation of the human lower limb motoneurones by group II muscle afferents. Exp Brain Res 109 (1996) 357-360
23. Marque P., Simonetta-Moreau M., Maupas E., and Roques C.F. Facilitation of transmission in heteronymous group II pathways in spastic hemiplegic patients. J Neurol Neurosurg Psychiatry 70 (2001) 36-42
24. Maupas E., Marque P., Roques C.F., and Simonetta-Moreau M. Modulation of the transmission in group II heteronymous pathways by tizanidine in spastic hemiplegic patients. J Neurol Neurosurg Psychiatry 75 (2004) 130-135
25. Mazzaro N., Nielsen J.F., Grey M.J., and Sinkjaer T. Decreased contribution from afferent feedback to the soleus muscle during walking in patients with spastic stroke. J Stroke Cerebrovasc Dis 16 (2007) 135-144
26. McPherson J.G., Ellis M.D., Heckman C.J., and Dewald J.P. Evidence for increased activation of persistent inward currents in individuals with chronic hemiparetic stroke. J Neurophysiol 100 (2008) 3236-3243
27. Meunier S., Pierrot-Deseilligny E., and Simonetta M. Pattern of monosynaptic heteronymous Ia connections in the human lower limb. Exp Brain Res 96 (1993) 534-544
28. Morisset V., and Nagy F. Plateau potential-dependent windup of the response to primary afferent stimuli in rat dorsal horn neurons. Eur J Neurosci 12 (2000) 3087-3095
29. Nardone A., and Schieppati M. Reflex contribution of spindle group Ia and II afferent input to leg muscle spasticity as revealed by tendon vibration in hemiparesis. Clin Neurophysiol 116 (2005) 1370-1381
30. Nickolls P., Collins D.F., Gorman R.B., Burke D., and Gandevia S.C. Forces consistent with plateau-like behaviour of spinal neurons evoked in patients with spinal cord injuries. Brain 127 (2004) 660-670
31. Nielsen J.B., Brittain J.S., Halliday D.M., Marchand-Pauvert V., Mazevet D., and Conway B.A. Reduction of common motoneuronal drive on the affected side during walking in hemiplegic stroke patients. Clin Neurophysiol 119 (2008) 2813-2818
32. Nielsen J.B., Crone C., and Hultborn H. The spinal pathophysiology of spasticity - from a basic science point of view. Acta Physiol 189 (2007) 171-180
33. Norton J.A., Bennett D.J., Knash M.E., Murray K.C., and Gorassini M.A. Changes in sensory-evoked synaptic activation of motoneurons after spinal cord injury in man. Brain 131 (2008) 1478-1491
34. Peat M., Dubo H.I., Winter D.A., Quanbury A.O., Steinke T., and Grahame R. Electromyographic temporal analysis of gait: hemiplegic locomotion. Arch Phys Med Rehabil 57 (1976) 421-425
35. Pierrot-Deseilligny E., and Burke D. The circuitry of the human spinal cord (2005), Cambridge University Press, New York
36. Rémy-Néris O., Denys P., Daniel O., Barbeau H., and Bussel B. Effect of intrathecal clonidine on group I and group II oligosynaptic excitation in paraplegics. Exp Brain Res 148 (2003) 509-514
37. Shiavi R., Bugle H.J., and Limbird T. Electromyographic gait assessment. Part 2: preliminary assessment of hemiparetic synergy patterns. J Rehabil Res Dev 24 (1987) 24-30
38. Simonetta-Moreau M., Marque P., Marchand-Pauvert V., and Pierrot-Deseilligny E. The pattern of excitation of human lower limb motoneurones by probable group II muscle afferents. J Physiol 517 (1999) 287-300
39. Smith M., and Perrier J.F. Intrinsic properties shape the firing pattern of ventral horn interneurons from the spinal cord of the adult turtle. J Neurophysiol 96 (2006) 2670-2677
40. Wall J.C., and Turnbull G.I. Gait asymmetries in residual hemiplegia. Arch Phys Med Rehabil 67 (1986) 550-553
41. Zehr E.P., Fujita K., and Stein R.B. Reflexes from the superficial peroneal nerve during walking in stroke subjects. J Neurophysiol 79 (1998) 848-858