메뉴 건너뛰기




Volumn 31, Issue 6, 2010, Pages 519-527

Inhibition of HLA-G Expression Via RNAi Abolishes Resistance of Extravillous Trophoblast Cell Line TEV-1 to NK Lysis

Author keywords

Extravillous trophoblast; HLA G; Immunosuppression; Natural killer cell; Pregnancy; RNA interference

Indexed keywords

CELL ANTIGEN; HLA C ANTIGEN; HLA E ANTIGEN; HLA G ANTIGEN; PROTEIN ILT2; PROTEIN ILT4; PROTEIN KIR2DL4; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

EID: 77952542134     PISSN: 01434004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.placenta.2010.03.008     Document Type: Article
Times cited : (35)

References (50)
  • 1
    • 33645098806 scopus 로고    scopus 로고
    • Mother's little helpers: mechanisms of maternal-fetal tolerance
    • Trowsdale J., and Betz A.G. Mother's little helpers: mechanisms of maternal-fetal tolerance. Nat Immunol 7 3 (2006) 241-246
    • (2006) Nat Immunol , vol.7 , Issue.3 , pp. 241-246
    • Trowsdale, J.1    Betz, A.G.2
  • 2
    • 34247173568 scopus 로고    scopus 로고
    • The changing maternal "self" hypothesis: a mechanism for maternal tolerance of the fetus
    • Adams K.M., Yan Z., Stevens A.M., and Nelson J.L. The changing maternal "self" hypothesis: a mechanism for maternal tolerance of the fetus. Placenta 28 5-6 (2007) 378-382
    • (2007) Placenta , vol.28 , Issue.5-6 , pp. 378-382
    • Adams, K.M.1    Yan, Z.2    Stevens, A.M.3    Nelson, J.L.4
  • 3
    • 45649083472 scopus 로고    scopus 로고
    • Defect in lipid rafts results in failed tolerance induction at the maternal-fetal interface: a possible cause for the recurrent spontaneous abortion
    • Chen L.J., Zhou H., and Zou L. Defect in lipid rafts results in failed tolerance induction at the maternal-fetal interface: a possible cause for the recurrent spontaneous abortion. Med Hypotheses 71 2 (2008) 275-278
    • (2008) Med Hypotheses , vol.71 , Issue.2 , pp. 275-278
    • Chen, L.J.1    Zhou, H.2    Zou, L.3
  • 4
    • 33748440547 scopus 로고    scopus 로고
    • Decidual NK cells regulate key developmental processes at the human fetal-maternal interface
    • Hanna J., Goldman-Wohl D., Hamani Y., Avraham I., Greenfield C., Natanson-Yaron S., et al. Decidual NK cells regulate key developmental processes at the human fetal-maternal interface. Nat Med 12 9 (2006) 1065-1074
    • (2006) Nat Med , vol.12 , Issue.9 , pp. 1065-1074
    • Hanna, J.1    Goldman-Wohl, D.2    Hamani, Y.3    Avraham, I.4    Greenfield, C.5    Natanson-Yaron, S.6
  • 5
    • 65649102625 scopus 로고    scopus 로고
    • NK cells detect changes in adaptive immunity within mouse decidua from gestation day eight
    • Hatta K., van den Heuvel M.J., and Croy B.A. NK cells detect changes in adaptive immunity within mouse decidua from gestation day eight. Placenta 30 6 (2009) 501-506
    • (2009) Placenta , vol.30 , Issue.6 , pp. 501-506
    • Hatta, K.1    van den Heuvel, M.J.2    Croy, B.A.3
  • 6
    • 7244245342 scopus 로고    scopus 로고
    • NK cells and trophoblasts: partners in pregnancy
    • Parham P. NK cells and trophoblasts: partners in pregnancy. J Exp Med 200 8 (2004) 951-955
    • (2004) J Exp Med , vol.200 , Issue.8 , pp. 951-955
    • Parham, P.1
  • 7
    • 67651097924 scopus 로고    scopus 로고
    • Intrauterine growth restriction, human placental development and trophoblast cell death
    • Scifres C.M., and Nelson D.M. Intrauterine growth restriction, human placental development and trophoblast cell death. J Physiol 587 Pt 14 (2009) 3453-3458
    • (2009) J Physiol , vol.587 , Issue.PART 14 , pp. 3453-3458
    • Scifres, C.M.1    Nelson, D.M.2
  • 9
    • 1842415448 scopus 로고    scopus 로고
    • Human histocompatibility leukocyte antigen (HLA)-G molecules inhibit NKAT3 expressing natural killer cells
    • Munz C., Holmes N., King A., Loke Y.W., Colonna M., Schild H., et al. Human histocompatibility leukocyte antigen (HLA)-G molecules inhibit NKAT3 expressing natural killer cells. J Exp Med 185 3 (1997) 385-391
    • (1997) J Exp Med , vol.185 , Issue.3 , pp. 385-391
    • Munz, C.1    Holmes, N.2    King, A.3    Loke, Y.W.4    Colonna, M.5    Schild, H.6
  • 10
    • 0033829539 scopus 로고    scopus 로고
    • HLA-G suppresses proliferation of CD4(+) T-lymphocytes
    • Bainbridge D.R., Ellis S.A., and Sargent I.L. HLA-G suppresses proliferation of CD4(+) T-lymphocytes. J Reprod Immunol 48 1 (2000) 17-26
    • (2000) J Reprod Immunol , vol.48 , Issue.1 , pp. 17-26
    • Bainbridge, D.R.1    Ellis, S.A.2    Sargent, I.L.3
  • 11
    • 0034660339 scopus 로고    scopus 로고
    • Cutting edge: soluble HLA-G1 triggers CD95/CD95 ligand-mediated apoptosis in activated CD8+ cells by interacting with CD8
    • Fournel S., Aguerre-Girr M., Huc X., Lenfant F., Alam A., Toubert A., et al. Cutting edge: soluble HLA-G1 triggers CD95/CD95 ligand-mediated apoptosis in activated CD8+ cells by interacting with CD8. J Immunol 164 12 (2000) 6100-6104
    • (2000) J Immunol , vol.164 , Issue.12 , pp. 6100-6104
    • Fournel, S.1    Aguerre-Girr, M.2    Huc, X.3    Lenfant, F.4    Alam, A.5    Toubert, A.6
  • 13
    • 45249090113 scopus 로고    scopus 로고
    • Novel HLA-G-binding leukocyte immunoglobulin-like receptor (LILR) expression patterns in human placentas and umbilical cords
    • McIntire R.H., Sifers T., Platt J.S., Ganacias K.G., Langat D.K., and Hunt J.S. Novel HLA-G-binding leukocyte immunoglobulin-like receptor (LILR) expression patterns in human placentas and umbilical cords. Placenta 29 7 (2008) 631-638
    • (2008) Placenta , vol.29 , Issue.7 , pp. 631-638
    • McIntire, R.H.1    Sifers, T.2    Platt, J.S.3    Ganacias, K.G.4    Langat, D.K.5    Hunt, J.S.6
  • 14
    • 0026575821 scopus 로고
    • Alternative splicing of HLA-G transcripts yields proteins with primary structures resembling both class I and class II antigens
    • Ishitani A., and Geraghty D.E. Alternative splicing of HLA-G transcripts yields proteins with primary structures resembling both class I and class II antigens. Proc Natl Acad Sci U S A 89 9 (1992) 3947-3951
    • (1992) Proc Natl Acad Sci U S A , vol.89 , Issue.9 , pp. 3947-3951
    • Ishitani, A.1    Geraghty, D.E.2
  • 15
    • 0030848809 scopus 로고    scopus 로고
    • Direct evidence to support the role of HLA-G in protecting the fetus from maternal uterine natural killer cytolysis
    • Rouas-Freiss N., Goncalves R.M., Menier C., Dausset J., and Carosella E.D. Direct evidence to support the role of HLA-G in protecting the fetus from maternal uterine natural killer cytolysis. Proc Natl Acad Sci U S A 94 21 (1997) 11520-11525
    • (1997) Proc Natl Acad Sci U S A , vol.94 , Issue.21 , pp. 11520-11525
    • Rouas-Freiss, N.1    Goncalves, R.M.2    Menier, C.3    Dausset, J.4    Carosella, E.D.5
  • 16
    • 9244226486 scopus 로고    scopus 로고
    • A study of HLA-G1 protection of porcine endothelial cells against human NK cell cytotoxicity
    • Wang S.S., Han J.Y., Wu X.W., Cao R.H., Qi H.G., Xia Z.X., et al. A study of HLA-G1 protection of porcine endothelial cells against human NK cell cytotoxicity. Transplant Proc 36 8 (2004) 2473-2474
    • (2004) Transplant Proc , vol.36 , Issue.8 , pp. 2473-2474
    • Wang, S.S.1    Han, J.Y.2    Wu, X.W.3    Cao, R.H.4    Qi, H.G.5    Xia, Z.X.6
  • 17
    • 0029917430 scopus 로고    scopus 로고
    • Protection from natural killer cell-mediated lysis by HLA-G expression on target cells
    • Pazmany L., Mandelboim O., Vales-Gomez M., Davis D.M., Reyburn H.T., and Strominger J.L. Protection from natural killer cell-mediated lysis by HLA-G expression on target cells. Science 274 5288 (1996) 792-795
    • (1996) Science , vol.274 , Issue.5288 , pp. 792-795
    • Pazmany, L.1    Mandelboim, O.2    Vales-Gomez, M.3    Davis, D.M.4    Reyburn, H.T.5    Strominger, J.L.6
  • 18
    • 0032524965 scopus 로고    scopus 로고
    • HLA-E surface expression depends on binding of TAP-dependent peptides derived from certain HLA class I signal sequences
    • Lee N., Goodlett D.R., Ishitani A., Marquardt H., and Geraghty D.E. HLA-E surface expression depends on binding of TAP-dependent peptides derived from certain HLA class I signal sequences. J Immunol 160 10 (1998) 4951-4960
    • (1998) J Immunol , vol.160 , Issue.10 , pp. 4951-4960
    • Lee, N.1    Goodlett, D.R.2    Ishitani, A.3    Marquardt, H.4    Geraghty, D.E.5
  • 20
    • 56649124517 scopus 로고    scopus 로고
    • Down-regulation of HLA-G boosted natural killer cell-mediated cytolysis in JEG-3 cells cultured in vitro
    • Sun L.L., Han Y., Chen J.H., and Yao Y.Q. Down-regulation of HLA-G boosted natural killer cell-mediated cytolysis in JEG-3 cells cultured in vitro. Fertil Steril 90 6 (2008) 2398-2405
    • (2008) Fertil Steril , vol.90 , Issue.6 , pp. 2398-2405
    • Sun, L.L.1    Han, Y.2    Chen, J.H.3    Yao, Y.Q.4
  • 21
    • 11144282643 scopus 로고    scopus 로고
    • HLA-E surface expression is independent of the availability of HLA class I signal sequence-derived peptides in human tumor cell lines
    • Palmisano G.L., Contardi E., Morabito A., Gargaglione V., Ferrara G.B., and Pistillo M.P. HLA-E surface expression is independent of the availability of HLA class I signal sequence-derived peptides in human tumor cell lines. Hum Immunol 66 1 (2005) 1-12
    • (2005) Hum Immunol , vol.66 , Issue.1 , pp. 1-12
    • Palmisano, G.L.1    Contardi, E.2    Morabito, A.3    Gargaglione, V.4    Ferrara, G.B.5    Pistillo, M.P.6
  • 22
    • 18144428330 scopus 로고    scopus 로고
    • Establishment and characterization of a human first-trimester extravillous trophoblast cell line (TEV-1)
    • Feng H.C., Choy M.Y., Deng W., Wong H.L., Lau W.M., Cheung A.N., et al. Establishment and characterization of a human first-trimester extravillous trophoblast cell line (TEV-1). J Soc Gynecol Investig 12 4 (2005) e21-e32
    • (2005) J Soc Gynecol Investig , vol.12 , Issue.4
    • Feng, H.C.1    Choy, M.Y.2    Deng, W.3    Wong, H.L.4    Lau, W.M.5    Cheung, A.N.6
  • 23
    • 0034665105 scopus 로고    scopus 로고
    • Structural relatedness of distinct determinants recognized by monoclonal antibody TP25.99 on beta 2-microglobulin-associated and beta 2-microglobulin-free HLA class I heavy chains
    • Desai S.A., Wang X., Noronha E.J., Zhou Q., Rebmann V., Grosse-Wilde H., et al. Structural relatedness of distinct determinants recognized by monoclonal antibody TP25.99 on beta 2-microglobulin-associated and beta 2-microglobulin-free HLA class I heavy chains. J Immunol 165 6 (2000) 3275-3283
    • (2000) J Immunol , vol.165 , Issue.6 , pp. 3275-3283
    • Desai, S.A.1    Wang, X.2    Noronha, E.J.3    Zhou, Q.4    Rebmann, V.5    Grosse-Wilde, H.6
  • 24
    • 38449097276 scopus 로고    scopus 로고
    • Pregnancy impairs the innate immune resistance to Salmonella typhimurium leading to rapid fatal infection
    • Pejcic-Karapetrovic B., Gurnani K., Russell M.S., Finlay B.B., Sad S., and Krishnan L. Pregnancy impairs the innate immune resistance to Salmonella typhimurium leading to rapid fatal infection. J Immunol 179 9 (2007) 6088-6096
    • (2007) J Immunol , vol.179 , Issue.9 , pp. 6088-6096
    • Pejcic-Karapetrovic, B.1    Gurnani, K.2    Russell, M.S.3    Finlay, B.B.4    Sad, S.5    Krishnan, L.6
  • 25
    • 72549090509 scopus 로고    scopus 로고
    • Pregnancy does not deter the development of a potent maternal protective CD8+ T-cell acquired immune response against Listeria monocytogenes despite preferential placental colonization
    • Krishnan L., Pejcic-Karapetrovic B., Gurnani K., Zafer A., and Sad S. Pregnancy does not deter the development of a potent maternal protective CD8+ T-cell acquired immune response against Listeria monocytogenes despite preferential placental colonization. Am J Reprod Immunol 63 1 (2010) 54-65
    • (2010) Am J Reprod Immunol , vol.63 , Issue.1 , pp. 54-65
    • Krishnan, L.1    Pejcic-Karapetrovic, B.2    Gurnani, K.3    Zafer, A.4    Sad, S.5
  • 26
    • 0033976570 scopus 로고    scopus 로고
    • HLA-G in the human placenta: expression and potential functions
    • Le Bouteiller P. HLA-G in the human placenta: expression and potential functions. Biochem Soc Trans 28 2 (2000) 208-212
    • (2000) Biochem Soc Trans , vol.28 , Issue.2 , pp. 208-212
    • Le Bouteiller, P.1
  • 27
    • 32144449707 scopus 로고    scopus 로고
    • Does 'soluble' HLA-G really exist? Another twist to the tale
    • Sargent I.L. Does 'soluble' HLA-G really exist? Another twist to the tale. Mol Hum Reprod 11 10 (2005) 695-698
    • (2005) Mol Hum Reprod , vol.11 , Issue.10 , pp. 695-698
    • Sargent, I.L.1
  • 28
    • 29144468668 scopus 로고    scopus 로고
    • Differential expression of alternatively spliced transcripts of HLA-G in human preimplantation embryos and inner cell masses
    • Yao Y.Q., Barlow D.H., and Sargent I.L. Differential expression of alternatively spliced transcripts of HLA-G in human preimplantation embryos and inner cell masses. J Immunol 175 12 (2005) 8379-8385
    • (2005) J Immunol , vol.175 , Issue.12 , pp. 8379-8385
    • Yao, Y.Q.1    Barlow, D.H.2    Sargent, I.L.3
  • 29
    • 18144407990 scopus 로고    scopus 로고
    • HLA-G and immune tolerance in pregnancy
    • Hunt J.S., Petroff M.G., McIntire R.H., and Ober C. HLA-G and immune tolerance in pregnancy. FASEB J 19 7 (2005) 681-693
    • (2005) FASEB J , vol.19 , Issue.7 , pp. 681-693
    • Hunt, J.S.1    Petroff, M.G.2    McIntire, R.H.3    Ober, C.4
  • 30
    • 40649124194 scopus 로고    scopus 로고
    • A caution on the use of HLA-G isoforms as markers of extravillous trophoblasts
    • James J.L., and Chamley L.W. A caution on the use of HLA-G isoforms as markers of extravillous trophoblasts. Placenta 29 3 (2008) 305-306
    • (2008) Placenta , vol.29 , Issue.3 , pp. 305-306
    • James, J.L.1    Chamley, L.W.2
  • 31
    • 0034041995 scopus 로고    scopus 로고
    • Surface expression of HLA-C antigen by human extravillous trophoblast
    • King A., Burrows T.D., Hiby S.E., Bowen J.M., Joseph S., Verma S., et al. Surface expression of HLA-C antigen by human extravillous trophoblast. Placenta 21 4 (2000) 376-387
    • (2000) Placenta , vol.21 , Issue.4 , pp. 376-387
    • King, A.1    Burrows, T.D.2    Hiby, S.E.3    Bowen, J.M.4    Joseph, S.5    Verma, S.6
  • 32
    • 0030988540 scopus 로고    scopus 로고
    • The human major histocompatibility complex class Ib molecule HLA-E binds signal sequence-derived peptides with primary anchor residues at positions 2 and 9
    • Braud V., Jones E.Y., and McMichael A. The human major histocompatibility complex class Ib molecule HLA-E binds signal sequence-derived peptides with primary anchor residues at positions 2 and 9. Eur J Immunol 27 5 (1997) 1164-1169
    • (1997) Eur J Immunol , vol.27 , Issue.5 , pp. 1164-1169
    • Braud, V.1    Jones, E.Y.2    McMichael, A.3
  • 33
    • 0035143984 scopus 로고    scopus 로고
    • HLA-G1 co-expression boosts the HLA class I-mediated NK lysis inhibition
    • Riteau B., Menier C., Khalil-Daher I., Martinozzi S., Pla M., Dausset J., et al. HLA-G1 co-expression boosts the HLA class I-mediated NK lysis inhibition. Int Immunol 13 2 (2001) 193-201
    • (2001) Int Immunol , vol.13 , Issue.2 , pp. 193-201
    • Riteau, B.1    Menier, C.2    Khalil-Daher, I.3    Martinozzi, S.4    Pla, M.5    Dausset, J.6
  • 34
    • 46749123555 scopus 로고    scopus 로고
    • Beyond the increasing complexity of the immunomodulatory HLA-G molecule
    • Carosella E.D., Favier B., Rouas-Freiss N., Moreau P., and Lemaoult J. Beyond the increasing complexity of the immunomodulatory HLA-G molecule. Blood 111 10 (2008) 4862-4870
    • (2008) Blood , vol.111 , Issue.10 , pp. 4862-4870
    • Carosella, E.D.1    Favier, B.2    Rouas-Freiss, N.3    Moreau, P.4    Lemaoult, J.5
  • 35
    • 0032799439 scopus 로고    scopus 로고
    • Role of HLA-G versus HLA-E on NK function: HLA-G is able to inhibit NK cytolysis by itself
    • Khalil-Daher I., Riteau B., Menier C., Sedlik C., Paul P., Dausset J., et al. Role of HLA-G versus HLA-E on NK function: HLA-G is able to inhibit NK cytolysis by itself. J Reprod Immunol 43 2 (1999) 175-182
    • (1999) J Reprod Immunol , vol.43 , Issue.2 , pp. 175-182
    • Khalil-Daher, I.1    Riteau, B.2    Menier, C.3    Sedlik, C.4    Paul, P.5    Dausset, J.6
  • 36
    • 54049151957 scopus 로고    scopus 로고
    • HLA-E: strong association with beta2-microglobulin and surface expression in the absence of HLA class I signal sequence-derived peptides
    • Lo Monaco E., Sibilio L., Melucci E., Tremante E., Suchanek M., Horejsi V., et al. HLA-E: strong association with beta2-microglobulin and surface expression in the absence of HLA class I signal sequence-derived peptides. J Immunol 181 8 (2008) 5442-5450
    • (2008) J Immunol , vol.181 , Issue.8 , pp. 5442-5450
    • Lo Monaco, E.1    Sibilio, L.2    Melucci, E.3    Tremante, E.4    Suchanek, M.5    Horejsi, V.6
  • 37
    • 33748994544 scopus 로고    scopus 로고
    • Cytotrophoblast stem cell lines derived from human embryonic stem cells and their capacity to mimic invasive implantation events
    • Harun R., Ruban L., Matin M., Draper J., Jenkins N.M., Liew G.C., et al. Cytotrophoblast stem cell lines derived from human embryonic stem cells and their capacity to mimic invasive implantation events. Hum Reprod 21 6 (2006) 1349-1358
    • (2006) Hum Reprod , vol.21 , Issue.6 , pp. 1349-1358
    • Harun, R.1    Ruban, L.2    Matin, M.3    Draper, J.4    Jenkins, N.M.5    Liew, G.C.6
  • 38
    • 63849192339 scopus 로고    scopus 로고
    • Human leucocyte antigen (HLA) expression of primary trophoblast cells and placental cell lines, determined using single antigen beads to characterize allotype specificities of anti-HLA antibodies
    • Apps R., Murphy S.P., Fernando R., Gardner L., Ahad T., and Moffett A. Human leucocyte antigen (HLA) expression of primary trophoblast cells and placental cell lines, determined using single antigen beads to characterize allotype specificities of anti-HLA antibodies. Immunology 127 1 (2009) 26-39
    • (2009) Immunology , vol.127 , Issue.1 , pp. 26-39
    • Apps, R.1    Murphy, S.P.2    Fernando, R.3    Gardner, L.4    Ahad, T.5    Moffett, A.6
  • 39
    • 58949089431 scopus 로고    scopus 로고
    • Dimerization of soluble HLA-G by IgG-Fc fragment augments ILT2-mediated inhibition of T-cell alloresponse
    • Zhong M., Weng X., Liang Z., Lu S., Li J., Chen X., et al. Dimerization of soluble HLA-G by IgG-Fc fragment augments ILT2-mediated inhibition of T-cell alloresponse. Transplantation 87 1 (2009) 8-15
    • (2009) Transplantation , vol.87 , Issue.1 , pp. 8-15
    • Zhong, M.1    Weng, X.2    Liang, Z.3    Lu, S.4    Li, J.5    Chen, X.6
  • 40
    • 0036719573 scopus 로고    scopus 로고
    • Natural killer cells and pregnancy
    • Moffett-King A. Natural killer cells and pregnancy. Nat Rev Immunol 2 9 (2002) 656-663
    • (2002) Nat Rev Immunol , vol.2 , Issue.9 , pp. 656-663
    • Moffett-King, A.1
  • 41
    • 0242652204 scopus 로고    scopus 로고
    • NK cell recognition of non-classical HLA class I molecules
    • Lopez-Botet M., Llano M., Navarro F., and Bellon T. NK cell recognition of non-classical HLA class I molecules. Semin Immunol 12 2 (2000) 109-119
    • (2000) Semin Immunol , vol.12 , Issue.2 , pp. 109-119
    • Lopez-Botet, M.1    Llano, M.2    Navarro, F.3    Bellon, T.4
  • 42
    • 0043205005 scopus 로고    scopus 로고
    • Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G
    • Shiroishi M., Tsumoto K., Amano K., Shirakihara Y., Colonna M., Braud V.M., et al. Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G. Proc Natl Acad Sci U S A 100 15 (2003) 8856-8861
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.15 , pp. 8856-8861
    • Shiroishi, M.1    Tsumoto, K.2    Amano, K.3    Shirakihara, Y.4    Colonna, M.5    Braud, V.M.6
  • 45
    • 0034075580 scopus 로고    scopus 로고
    • HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells
    • King A., Allan D.S., Bowen M., Powis S.J., Joseph S., Verma S., et al. HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells. Eur J Immunol 30 6 (2000) 1623-1631
    • (2000) Eur J Immunol , vol.30 , Issue.6 , pp. 1623-1631
    • King, A.1    Allan, D.S.2    Bowen, M.3    Powis, S.J.4    Joseph, S.5    Verma, S.6
  • 46
    • 44849105165 scopus 로고    scopus 로고
    • Conformation of human leucocyte antigen-C molecules at the surface of human trophoblast cells
    • Apps R., Gardner L., Hiby S.E., Sharkey A.M., and Moffett A. Conformation of human leucocyte antigen-C molecules at the surface of human trophoblast cells. Immunology 124 3 (2008) 322-328
    • (2008) Immunology , vol.124 , Issue.3 , pp. 322-328
    • Apps, R.1    Gardner, L.2    Hiby, S.E.3    Sharkey, A.M.4    Moffett, A.5
  • 47
    • 7244234068 scopus 로고    scopus 로고
    • Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive success
    • Hiby S.E., Walker J.J., O'Shaughnessy K.M., Redman C.W., Carrington M., Trowsdale J., et al. Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive success. J Exp Med 200 8 (2004) 957-965
    • (2004) J Exp Med , vol.200 , Issue.8 , pp. 957-965
    • Hiby, S.E.1    Walker, J.J.2    O'Shaughnessy, K.M.3    Redman, C.W.4    Carrington, M.5    Trowsdale, J.6
  • 48
    • 16344366533 scopus 로고    scopus 로고
    • HLA-G up-regulates ILT2, ILT3, ILT4, and KIR2DL4 in antigen presenting cells, NK cells, and T cells
    • LeMaoult J., Zafaranloo K., Le Danff C., and Carosella E.D. HLA-G up-regulates ILT2, ILT3, ILT4, and KIR2DL4 in antigen presenting cells, NK cells, and T cells. FASEB J 19 6 (2005) 662-664
    • (2005) FASEB J , vol.19 , Issue.6 , pp. 662-664
    • LeMaoult, J.1    Zafaranloo, K.2    Le Danff, C.3    Carosella, E.D.4
  • 49
    • 77952294287 scopus 로고    scopus 로고
    • ILT2/HLA-G interaction impairs NK-cell functions through the inhibition of the late but not the early events of the NK-cell activating synapse
    • 10.1096/fj.09-135194 [Epub ahead of print]
    • Favier B., Lemaoult J., Lesport E., and Carosella E.D. ILT2/HLA-G interaction impairs NK-cell functions through the inhibition of the late but not the early events of the NK-cell activating synapse. FASEB J (2009) 10.1096/fj.09-135194 [Epub ahead of print]
    • (2009) FASEB J
    • Favier, B.1    Lemaoult, J.2    Lesport, E.3    Carosella, E.D.4
  • 50
    • 76749133164 scopus 로고    scopus 로고
    • Review: functional role of uterine natural killer (uNK) cells in human early pregnancy decidua
    • Lash G.E., Robson S.C., and Bulmer J.N. Review: functional role of uterine natural killer (uNK) cells in human early pregnancy decidua. Placenta 31 S (2010) S87-S92
    • (2010) Placenta , vol.31 , Issue.SUPPL
    • Lash, G.E.1    Robson, S.C.2    Bulmer, J.N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.