A Mechanism for the induction of renal tumours in male Fischer 344 rats by short-chain chlorinated paraffins

Archives of Toxicology

Volumn 84, Issue 3, 2010, Pages 233-243

  Warnasuriya, Gayathri D ^a   Elcombe, Barbara M ^b   Foster, John R ^c   Elcombe, Clifford R ^b  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b CXR Biosciences Ltd   (United Kingdom)

^c ASTRAZENECA   (United Kingdom)

Author keywords

1,4 Dichlorobenzene; Alpha 2 urinary globulin nephropathy; Chlorowax 500C; D Limonene; Short chain chlorinated paraffins

Indexed keywords

ALPHA 2 GLOBULIN; CHLOROWAX 500C; DICHLOROBENZENE; LIMONENE; PARAFFIN; POLYCHLOROTRIDECANE; SHORT CHAIN CHLORINATED PARAFFIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; DOWN REGULATION; FEMALE; FISCHER 344 RAT; GEL FILTRATION CHROMATOGRAPHY; GENETIC TRANSCRIPTION; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; KIDNEY; KIDNEY CELL; KIDNEY TUMOR; LIVER; MALE; MULTIPLEX POLYMERASE CHAIN REACTION; NONHUMAN; PEROXISOME; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS REGULATION; PROTEIN URINE LEVEL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR MODEL; TWO DIMENSIONAL GEL ELECTROPHORESIS;

ALPHA-GLOBULINS; ANIMALS; CARCINOGENS; CELL PROLIFERATION; CHLOROBENZENES; CYCLOHEXENES; DISEASE MODELS, ANIMAL; DOWN-REGULATION; FEMALE; HYDROCARBONS, CHLORINATED; KIDNEY; KIDNEY NEOPLASMS; LIVER; MALE; PEROXISOMES; PROTEIN BINDING; RATS; RATS, INBRED F344; TERPENES; TRANSCRIPTION, GENETIC;

MUS; RATTUS;

EID: 77952541164     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-009-0489-9     Document Type: Article

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