Urethral Carcinoma and Hyperplasia in Male and Female B6C3F1 Mice Treated With 3,3′,4,4′-Tetrachloroazobenzene (TCAB)

Toxicologic Pathology

Volumn 38, Issue 3, 2010, Pages 372-381

  Singh, B P ^a   Nyska, A ^b   Kissling, G E ^a   Lieuallen, W ^c   Johansson, S L ^d   Malarkey, D E ^a   Hooth, M J ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b TEL AVIV UNIVERSITY   (Israel)

^c CHARLES RIVER LABORATORIES   (United States)

^d NEBRASKA MEDICAL CENTER   (United States)

Author keywords

3, 3 , 4, 4 tetrachloroazobenzene (TCAB); carcinoma; mice; transitional cell carcinoma; urethra

Indexed keywords

3,3',4,4' TETRACHLOROAZOBENZENE; ACETONE; CORN OIL; HERBICIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INVASION; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CELL HYPERPLASIA; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; LONG TERM EXPOSURE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SURVIVAL RATE; TRANSITIONAL CELL CARCINOMA; URETHRA CARCINOMA; URINARY TRACT CARCINOMA; URINARY TRACT OBSTRUCTION; UROGENITAL SYSTEM;

ANIMALS; AZO COMPOUNDS; CARCINOGENS; CARCINOMA, TRANSITIONAL CELL; CHLOROBENZENES; FEMALE; HERBICIDES; HYPERPLASIA; KIDNEY DISEASES; MALE; MICE; URETERAL NEOPLASMS; URETHRAL DISEASES; URETHRAL NEOPLASMS; URINARY BLADDER NEOPLASMS;

ANIMALIA; MUS; ZEA MAYS;

EID: 77952522264     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1177/0192623310362708     Document Type: Article

References (47)

1. Abbott B. D. Birnbaum L. S. (1990). Effects of TCDD on embryonic ureteric epithelial EGF receptor expression and cell proliferation. Teratology 41, 71–84.
2. Abbott B. D. Birnbaum L. S. Pratt R. M. (1987). TCDD-induced hyperplasia of the ureteral epithelium produces hydronephrosis in murine fetuses. Teratology 35, 329–34.
3. Bailer A. J. Portier C. J. (1988). Effects of treatment-induced mortality and tumor-induced mortality on tests for carcinogenicity in small samples. Biometrics 44, 417–31.
4. Bartha R. Pramer D. (1969). Transformation of the herbicide methyl-N-(3,4-dichlorophenyl)-carbamate (Swep) in soil. Bull Environ Contam Toxicol 4, 240–45.
5. R., Bartha, H.H.B., Linke, D., Pramer, Pesticide transformations: Production of chloroazobenzenes from chloroanilines, Science, (1968), 161, 582-583
6. Bieler G. S. Williams R. L. (1993). Ratio estimates, the delta method, and quantal response tests for increased carcinogenicity. Biometrics 49, 793–801.
7. Boorman G. A. Montgomery C. A. Jr. Eustis S. L. Wolfe M. J. McConnell E. E. Hardisty J. F. (1985). Quality assurance in pathology for rodent carcinogenicity studies. In Handbook of Carcinogen Testing (Milman H. A. Weisburger E. K., eds.), pp. 345–57. Noyes Publications, Park Ridge, NJ.
8. Bunce N. J. Corke C. T. Merrick R. L. Bright J. H. (1979). 3,3′,4,4′-Tetrachloroazobenzene as a contaminant in commercial propanil. Chemosphere 8, 283–84.
9. Choi S. S. H. Miller M. A. Harper P. A. (2006). In utero exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin induces amphiregulin gene expression in the developing mouse ureter. Toxicol Sci 94, 163–74.
10. Cox D. R. (1972). Regression models and life-tables. J R Stat Soc B34, 187–220.
11. El-Marjou A. Delouvtee A. Thiery J. P. Radvanyi F. (2001). Involvement of epidermal growth factor receptor in chemically induced mouse bladder tumour progression. Carcinogenesis 21, 2211–18.
12. Food Drug Administration. (1987). Good laboratory practice regulations. Final rule. 21 CFR 58. Fed Reg 52, 33768–82.
13. Gaillard E. T. (1999). Ureter, urinary bladder, and urethra. In Pathology of the Mouse. Reference and Atlas (Maronpot R. R. Boorman G. A. Gaul B. W., eds.). pp. 235–58. Cache River Press, Vienna, IL.
14. Grossblatt N. (1996). Guide for the Care and Use of Laboratory Animals. Washington, DC: National Academy Press.
15. Hill R. H. Jr. Rollen Z. J. Kimbrough R. D. Groce D. F. Needham L. L. (1981). Tetrachloroazobenzene in 3,4-dichloroaniline and its herbicidal derivatives: Propanil, diuron, linuron, and neburon. Arch Environ Health 36, 11–14.
16. International Agency for Research on Cancer (IARC) (1987). IARC Monographs on the Evaluation of the Carcinogenic Risks to Humans. Overall Evaluations of Carcinogenicity: An Updating of IARC Monographs Volumes 1 to 42 (Suppl. 7). IARC Publications, Lyon, France.
17. Jokinen M. P. (1990). Urinary bladder, ureter, and urethra. In Pathology of the Fischer Rat. Reference and Atlas (Boorman G. A. Eustis S. L. Elwell M. R. Montgomery C. A. Jr. MacKenzie W. F., eds.), pp. 109–26. Academic Press, Inc., San Diego.
18. Kearney P. C. Smith R. J. Jr. Plimmer J. R. Guardia F. S. (1970). Propanil and TCAB residues in rice soils. Weed Sci 18, 464–66.
19. Lay M. M. Ilnicki R. D. (1974). Peroxidase activity and propanil degradation in soil. Weed Res 14, 111–13.
20. Lopez-Beltran A. Knowles M. A. Sauter G. Sidransky D. Gasser T. Cordon-Cardo C. Hartman A. Jones P.A. Schmitz-Dräger B. J. Cairns P. Helpap B. Simon R. Ayala A. G. Amin M. B. Tamboli P. Tyczynski J. E. (2004). Infiltrating urothelial carcinoma. In World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs (Eble J. N. Sauter G. Epstein J. I. Sesterhenn I. A., Eds.). pp. 93–109, IARC Press, Lyon, France.
21. Meuten D. J. (2002). Tumors of the urinary system. In Tumors in Domestic Animals (Meuten D. J., ed.). pp. 509–46. Iowa State University Press, Ames, Iowa.
22. Meuten D. J. Everitt J. Inskeep W. Jacobs R. M. Peleteiro M. Thompson K. G. (2004). Histological Classification of Tumors of the Urinary System of Domestic Animals. pp. 26–32. 2nd series ed. Armed Forces Institute of Pathology, Washington D.C.
23. Miller G. C. Zisook R. Zepp R. (1980). Photolysis of 3,4-dichloroaniline in natural waters. J Agric Food Chem 28, 1053–56.
24. National Cancer Institute (NCI) (1977). Bioassays of Nitrilotriacetic Acid (NTA) and Nitrilotriacetic Acid, Trisodium Salt, Monohydrate (Na3NTA•H2O) for Possible Carcinogenicity (CAS No. 139-13-9 (NTA), CAS No. 18662-53-8 (Na3NTA•H2O). Technical Report Series No. 6. NIH Publication No. 77-806. U.S. Department of Health, Education, and Welfare, Public Health Service, National Institutes of Health, Bethesda, MD.
25. National Cancer Institute (NCI) (1978a). Bioassay of o-Anisidine Hydrochloride for Possible Carcinogenicity (CAS No. 134-29-0). Technical Report Series No. 89. NIH Publication No. 78-1339. U.S. Department of Health, Education, and Welfare, Public Health Service, National Institutes of Health, Bethesda, MD.
26. National Cancer Institute (NCI) (1978b). Bioassay of 4-Chloro-o-phenylenediamine for Possible Carcinogenicity (CAS No. 95-83-0). Technical Report Series No. 63. NIH Publication No. 78-1313. U.S. Department of Health, Education, and Welfare, Public Health Service, National Institutes of Health, Bethesda, MD.
27. National Cancer Institute (NCI) (1979). Bioassay of p-cresidine for Possible Carcinogenicity (CAS No. 120-71-8). Technical Report Series No. 142. NIH Publication No. 79-1397. U.S. Department of Health, Education, and Welfare, Public Health Service, National Institutes of Health, Bethesda, MD.
28. National Toxicology Program (NTP) (1982). Carcinogenesis Bioassay of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (CAS No. 1746-01-6) in Osborne-Mendel Rats and B6C3F1 Mice (Gavage Study). Technical Report Series No. 209. NIH Publication No. 82-1765. U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, Research Triangle Park, NC, and Bethesda, MD.
29. National Toxicology Program (NTP) (1985). Toxicology and Carcinogenesis Studies of Telone II® (Technical Grade 1,3-Dichloropropene [CAS No. 542-75-6] Containing 1.0% Epichlorohydrin as a Stabilizer) in F344/N Rats and B6C3F1 Mice (Gavage Studies). Technical Report Series No. 269. NIH Publication No. 85-2525. U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, Research Triangle Park, NC.
30. National Toxicology Program (NTP) (1989). Toxicology and Carcinogenesis Studies of Para-Chloroaniline Hydrochloride (CAS No. 20265-96-7) in F344/N Rats and B6C3F1 Mice (Gavage Studies). Technical Report Series No. 351. NIH Publication No. 89-2806. U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, Research Triangle Park, NC.
31. National Toxicology Program (NTP) (1998). Toxicity Studies of 3,3′,4,4′- Tetrachloroazobenzene (CAS No. 14047-09-7) Administered by Gavage to F344/N Rats and B6C3F1 Mice. Toxicity Report Series No. 65. NIH Publication No. 99-3945. U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, Research Triangle Park, NC.
32. National Toxicology Program (NTP) (2009). Toxicology and Carcinogenesis Studies of 3,3′,4,4′-Tetrachloroazobenzene (CAS No. 14047-09-7) in Sprague Dawley rats and B6C3F1 mice (Gavage studies). Toxicity Report Series No. 558. NIH Publication No. 09-5899. U. S. Department of Health and Human Services, Public Health Service, National Institutes of Health, Research Triangle Park, NC.
33. Parr M. B. Ren H. P. Russell L. D. Prins G. S. Parr E. L. (1992). Urethral glands of the male mouse contain secretory component and immunoglobulin A plasma cells and are targets of testosterone. Biol Reprod 47, 1031–39.
34. Parr M. B. de França L. R. Kepple L. Ying L. Parr E. L. Russell L. D. (1994). The urethral glands of male mice in relation to depletion of secretory granules upon mating. J Reprod Fertil 101, 675–80.
35. Piegorsch W. W. Bailer A. J. (1997). Statistics for Environmental Biology and Toxicology, Section 6.3.2. Chapman and Hall, London, UK.
36. Pillai U. A. Ziegler T. L. Wang D. X. Kattnig M. J. McClure T. Liebler D. C. Mayersohn M. Sipes I. G. (1996). 3,3N,4,4N-Tetrachloroazobenzene absorption, disposition, and metabolism in male Fischer 344 rats. Drug Metab Dispos 24, 238–44.
37. Poland A. Clover E. Kende A. S. DeCamp M. Giandomenico C. M. (1976). 3,4,3′,4′-Tetrachloroazoxybenzene and azobenzene: potent inducers of aryl hydrocarbon hydroxylase. Science 194, 627–630.
38. Portier C. J. Bailer A. J. (1989). Testing for increased carcinogenicity using a survival-adjusted quantal response test. Fundam Appl Toxicol 12, 731–37.
39. Portier C. J. Hedges J. C. Hoel D. G. (1986). Age-specific models of mortality and tumor onset for historical control animals in the National Toxicology Program’s carcinogenicity experiments. Cancer Res 46, 4372–78.
40. Sundström G. Jansson B. Renberg L. (1978). Determination of the toxic impurities 3,3′,4,4′-tetrachloroazobenzene and 3,3′,4,4′-tetrachloroazoxybenzene in commercial diuron, linuron, and 3,4-dichloroaniline samples. Chemosphere 12, 973–79.
41. Tarone R. E. (1975). Tests for trend in life table analysis. Biometrika 62, 679–82.
42. Taylor J. S. Wuthrich R. C. Lloyd K. M. Poland A. (1977). Chloracne from manufacture of a new herbicide. Arch Dermatol 113, 616–19.
43. U. S. Environmental Protection Agency (U.S. EPA) (1985). Health and Environmental Effects Profile for TCAB, TCAOB, and TCHB. EPA/600/X-85/394. Environmental Criteria and Assessment Office, Office of Health and Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Cincinnati, OH.
44. U. S. Environmental Protection Agency (U.S. EPA) (2006). Amendment to Reregistration Eligibility Decision (RED) for Propanil (March 2006) and the Propanil:/RED (September 2003), 5. Available at http://www.epa.gov/pesticides/reregistration/REDs/propanil_red_combined.pdf. U.S. Environmental Protection Agency, Washington D.C.
45. Van Birgelen A. P. J. M. Hébert C. D. Wenk M. L. Grimes L. K. Chapin R. E. Mahler J. Travlos G. S. Bucher J. R. (1999). Toxicity of 3,3′,4,4′-tetrachloroazobenzene in rats and mice. Toxicol Appl Pharmacol 156, 147–59.
46. Wolf J. C. (2002). Characteristics of the spectrum of proliferative lesions observed in the kidney and urinary bladder of Fischer 344 rats and B6C3F1 mice. Toxicol Path 30, 657–62.
47. Worobey B. L. (1984). Fate of 3,3′,4,4′-tetrachloroazobenzene in soybean plants grown in treated soils. Chemosphere 13, 1103–11.