The Nf-actin gene is an important factor for food-cup formation and cytotoxicity of pathogenic Naegleria fowleri

Parasitology Research

Volumn 106, Issue 4, 2010, Pages 917-924

  Sohn, Hae Jin ^a   Kim, Jong Hyun ^a   Shin, Myeong Heon ^b   Song, Kyoung Ju ^b   Shin, Ho Joon ^a  

^a Ajou University School of Medicine   (South Korea)

^b Hallym Unversity College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ANTISENSE OLIGONUCLEOTIDE; CYTOCHALASIN D; POLYCLONAL ANTIBODY; RECOMBINANT PROTEIN; PROTOZOAL DNA; PROTOZOAL PROTEIN; VIRULENCE FACTOR;

ACTIN POLYMERIZATION; AMOEBASTOME; ANIMAL CELL; ANTIBODY PRODUCTION; ARTICLE; BAGG ALBINO MOUSE; CHO CELL; COCULTURE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; FOOD CUP FORMATION; GENE EXPRESSION; GENE SEQUENCE; IMMUNIZATION; IMMUNOFLUORESCENCE TEST; MOLECULAR CLONING; NAEGLERIA FOWLERI; NAEGLERIA GRUBERI; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PSEUDOPODIUM; SEQUENCE ALIGNMENT; TARGET CELL DESTRUCTION; TROGOCYTOSIS; TROPHOZOITE; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; CRICETULUS; DNA SEQUENCE; FLUORESCENCE MICROSCOPY; GENETICS; HAMSTER; MOLECULAR GENETICS; MOUSE; PATHOGENICITY; PHAGOCYTOSIS; PHYSIOLOGY; SEQUENCE HOMOLOGY;

CRICETULUS GRISEUS; MAMMALIA; MUS; NAEGLERIA FOWLERI; NAEGLERIA GRUBERI;

ACTINS; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CHO CELLS; CLONING, MOLECULAR; CRICETINAE; CRICETULUS; CYTOPLASM; DNA, PROTOZOAN; MICE; MICE, INBRED BALB C; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; NAEGLERIA FOWLERI; PHAGOCYTOSIS; PROTOZOAN PROTEINS; PSEUDOPODIA; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; VIRULENCE FACTORS;

EID: 77952495209     PISSN: 09320113     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00436-010-1760-y     Document Type: Article

References (22)

1. Alsam S, Sissons J, Dudley R, Khan NA (2005) Mechanisms associated with Acanthamoeba castellanii (T4) phagocytosis. Parasitol Res 96:402-409
2. Anderson K, Jamieson A (1972) Primary amoebic meningoencephalitis. Lancet 19:379
3. Apley J, Clarke SK, Roome AP, Sandry SA, Saygi G, Silk B, Warhurst DC (1970) Primary amoebic meningoencephalitis in Britain. Br Med J 7:596-599
4. Baldo ET, Moon EK, Kong HH, Chung DI (2005) Acanthamoeba healyi: molecular cloning and characterization of a coronin homologue, an actin-related protein. Exp Parasitol 110:114-122
5. Bretscher A (1991) Microfilaments structure and function in the cortical cytoskeleton. Annu Rev Cell Biol 7:337-374
6. Brown T (1978) Observations by light microscopy on the cytopathogenicity of Naegleria fowleri in mouse embryo cell cultures. J Med Microbiol 11:249-259
7. Brown T (1979) Inhibition by amoeba-specific antiserum and by cytochalasin B of the cytopathogenicity of Naegleria fowleri in mouse embryo cell cultures. J Med Microbiol 12:355-362
8. Carter RF (1968) Primary amoebic meningoencephalitis: clinical, pathological and epidemiological features of six fatal cases. J Pathol Bacteriol 96:1-25
9. Culbertson CG (1970) Pathogenic Naegleria and Hartmannella (Acanthamoeba). Ann N Y Acad Sci 74:1018-1022
10. De Jonckheere JF (1980) Growth characteristics, cytopathic effect in cell culture, and virulence in mice of 36 type strains belonging to 19 different Acanthamoebae spp. Appl Environ Microbiol 39:681-685
11. González-Robles A, Castañón G, Hernández- Ramírez VI, Salazar-Villatoro L, González-Lázaro M, Omaña-Molina M, Talamás-Rohana P, Martínez-Palomo A (2008) Acanthamoeba castellanii: identification and distribution of actin cytoskeleton. Exp Parasitol 119:411-417
12. Gumbiner BM (1996) Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell 84:345-357
13. John DT, Cole TB Jr, Marciano-Cabral F (1984) Sucker-like structures on the pathogenic amoeba Naegleria fowleri. Appl Environ Microbiol 47:12-14
14. John DT, Cole TB Jr, Bruner RA (1985) Amebostomes of Naegleria fowleri. J Protozool 32:12-19
15. Kang SY, Song KJ, Jeong SR, Kim JH, Park S, Kim K, Kwon MS, Shin HJ (2005) Role of the Nfa1 protein in pathogenic Naegleria fowleri co-cultured with CHO target cells. Clin Diagn Lab Immunol 12:873-876
16. Marciano-Cabral F (1988) Biology of Naegleria spp. Microbiol Rev 52:114-133
17. Marciano-Cabral FM, Fulford DE (1986) Cytopathology of pathogenic and nonpathogenic Naegleria species for cultured rat neuroblastoma cells. Appl Environ Microbiol 51:1133-1137
18. Marciano-Cabral F, John DT (1983) Cytopathogenicity of Naegleria fowleri for rat neuroblastoma cell cultures: scanning electron microscopy study. Infect Immun 40:1214-1217
19. Shin HJ, Im KI (2004) Pathogenic free-living amoebae in Korea. Korean J Parasitol 42:93-119
20. Shin HJ, Cho MS, Jung SY, Kim HI, Park S, Kim HJ, Im KI (2001) Molecular cloning and characterization of a gene encoding a 13.1 kDa antigenic protein of Naegleria fowleri. J Eukaryot Microbiol 48:713-717
21. Swanson JA, Baer SC (1995) Phagocytosis by zippers and triggers. Trends Cell Biol 5:89-93
22. Voigt H, Guillén N (1999) New insights into the role of the cytoskeleton in phagocytosis of Entamoeba histolytica. Cell Microbiol 1:195-203