Vitamin D-1α-hydroxylase and vitamin D-24-hydroxylase in benign and malign breast tissue

European Journal of Gynaecological Oncology

Volumn 31, Issue 2, 2010, Pages 151-155

  Cordes, T ^a   Fischer, D ^a   Thill, M ^a   Becker, S ^a   Friedrich, M ^b   Salehin, D ^b  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^b HELIOS KLINIKUM KREFELD   (Germany)

Author keywords

1 hydroxylase; 24 hydroxylase; Breast cancer; Breast tissue; Vitamin D3

Indexed keywords

OXYGENASE; RNA; UNCLASSIFIED DRUG; VITAMIN D; VITAMIN D 1ALPHA HYDROXYLASE; VITAMIN D 24 HYDROXYLASE; ISOENZYME; STEROID MONOOXYGENASE; VITAMIN D 1 ALPHA HYDROXYLASE; VITAMIN D 1-ALPHA HYDROXYLASE; VITAMIN D 24-HYDROXYLASE;

ADULT; AGED; ARTICLE; BREAST; BREAST CANCER; FEMALE; HUMAN; HUMAN TISSUE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ALTERNATIVE RNA SPLICING; BREAST TUMOR; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MIDDLE AGED; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADULT; AGED; ALTERNATIVE SPLICING; BLOTTING, WESTERN; BREAST; BREAST NEOPLASMS; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; ISOENZYMES; MIDDLE AGED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STEROID HYDROXYLASES;

EID: 77952480456     PISSN: 03922936     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Ferlayj J., Bray F., Sankila R., Parkin D., GLOBOCAN: "Cancer incidence, mortality and prevalence worldwide". Version 2.0., Lyon, IARC Press, 2002.
2. Cui Y., Rohan TE.: "Vitamin D, calcium, and breast cancer risk: a review". Cancer Epidemiol Biomarkers Prev., 2002, 15, 1427.
3. Colston K.W., Hansen CM.: "Mechanisms implicated in the growth regulatory effects of vitamin D in breast cancer". Endocr. Relat Cancer, 2002, 9, 45.
4. 3-24-hydroxylase in rat osteoblasts". Endocrinology, 1994, 134, 1794. (Pubitemid 24110739)
5. Mawer E.B., Walls J., Howell A., Davies M., Ratcliffe W.A., Bundred N.J.: "Serum 1,25-dihydroxyvitamin D may be related inversely to disease activity in breast cancer patients with bone metastases". J. Clin. Endocrinol. Metab., 1997, 82, 118. (Pubitemid 27021281)
6. Bertone-Johnson E.R., Chen W.Y., Holick M.F., Hollis B.W., Colditz G.A., Willett W.C., Hankinson S.E.: "Plasma 25-hydroxy vitamin D and 1,25-dihydroxyvitamin D and risk of breast cancer". Cancer Epidemiol. Biomarkers Prev., 2005, 14, 1991.
7. Lowe L.C., Guy M., Mansi J.L., Peckitt C., Bliss J., Wilson R.G., Colston K.W.: "Plasma 25-hydroxy vitamin D concentrations, vitamin D receptor genotype and breast cancer risk in a UK Caucasian population". Eur. J. Cancer, 2005, 41, 1164.
8. Colston K.W., Lowe L.C., Mansi J.L., Campbell M.J.: "Vitamin D status and breast cancer risk". Anticancer Res., 2006, 26 (4A), 2573.
9. Friedrich M., Rafi L., Mitschele T., Tilgen W., Schmidt W., Reichrath J.: "Analysis of the vitamin D system in cervical carcinomas, breast cancer and ovarian cancer". Recent Results Cancer Res., 2003, 164, 239.
10. Zehnder D., Bland R., Williams M.C., McNinch R.W., Howie A.J., Stewart P.M., Hewison M.: "Extrarenal expression of 25-hydroxyvitamin D(3)-1α-hydroxylase". J. Clin. Endocrinol. Metab., 2001, 86, 888.
11. Welsh J., Wietzke JA., Zinser G.M., Byrne B., Smith K., Narvaez C.J.: "Vitamin D-3 receptor as a target for breast cancer prevention". J. Nutr., 2003, 133, 2425.
12. Hewison M., Zehnder D., Bland R., Stewart P.M.: "1α- Hydroxylase and the action of vitamin D". J. Mol. Endocrinol., 2000, 25, 141.
13. Hewison M., Zehnder D., Chakraverty R., Adams J.S.: "Vitamin D and barrier function: a novel role for extra-renal 1α-hydroxylase". Mol. Cell. Endocrinol., 2004, 275, 31.
14. Stimpfl M., Tong D., Fasching B., Schuster E., Obermair A., Leodolter S., Zeillinger R.: "Vascular endothelial growth factor splice variants and their prognostic value in breast and ovarian cancer". Clin. Cancer Res., 2002, 8, 2253.
15. Diesel B., Radermacher J., Bureik M., Bernhardt R., Seifert M., Reichrath J. et al.: "Vitamin D(3) metabolism in human glioblastoma multiforme: functionality of CYP27B1 splice variants, metabolism of calcidiol, and effect of calcitriol". Clin. Cancer Res., 2005, 11, 5370.
16. Diesel B., Seifert M., Radermacher J., Fischer U., Tilgen W., Reichrath J., Meese E.: "Towards a complete picture of splice variants of the gene for 25-hydroxyvitamin D31alpha-hydroxylase in brain and skin cancer". J. Steroid. Biochem. Mol. Biol., 2005, 89-90, 527.
17. Maas R.M., Reus K., Diesel B., Steudel W.I., Feiden W., Fischer U., Meese E.: "Amplification and expression of splice variants of the gene encoding the P450 cytochrome 25-hydroxyvitamin D(3) 1,alpha-hydroxylase (CYP 27B1) in human malignant glioma". Clin. Cancer Res., 2001, 7, 868.
18. Livak K.J., Schmittgen T.D.: "Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T))". Method Methods, 2001, 4, 402.
19. Ren S., Nguyen L., Wu S., Encinas C., Adams J.S., Hewison M.: "Alternative splicing of vitamin D-24-hydroxylase: a novel mechanism for the regulation of extrarenal 1,25-dihydroxyvitamin D synthesis". J. Biol. Chem., 2005, 27, 280, 20604.
20. Friedrich M., Diesing D., Cordes T., Fischer D., Becker S., Chen T.C. et al.: "Analysis of 25-hydroxyvitamin D3-1alpha-hydroxylase in normal and malignant breast tissue". Anticancer Res., 2006, 26, 2615.
21. Ner-Gaon H., Halachmi R., Savaldi-Goldstein S., Rubin E., Ophir R., Fluhr R.: "Intron retention is a major phenomenon in alternative splicing in Arabidopsis". Plant J., 2004, 39, 877. (Pubitemid 39320560)
22. Hiller M., Huse K., Platzer M., Backofen R.: "Non-EST based prediction of exon skipping and intron retention events using Pfam information". Nucleic Acids Res., 2005, 33, 5611.
23. Anderson M.G., Nakane M., Ruan X., Kroeger P.E., Wu-Wong J.R.: "Expression of VDR and CYP24A1 mRNA in human tumors". Cancer Chemother. Pharmacol., 2006, 57, 234. (Pubitemid 41779843)
24. Townsend K., Banwell CM., Guy M., Colston K.W., Mansi J.L., Stewart P.M. et al.: "Autocrine metabolism of vitamin D in normal and malignant breast tissue". Clin. Cancer Res., 2005, 11, 3579.
25. Albertson D.G., Ylstra B., Segraves R., Collins C., Dairkee S.H., Kowbel D., Kuo W.L., Gray J.W., Pinkel D.: "Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene". Nat. Genet., 2000, 25, 144. (Pubitemid 30394982)
26. Grant W.B.: "The likely role of vitamin D from solar ultraviolet-B irradiance in increasing cancer survival". Anticancer Res., 2006, 26, 2605.