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Volumn 25, Issue 6, 2010, Pages 588-595

Apathy is a prominent neuropsychiatric feature of radiological white-matter changes in patients with dementia

Author keywords

Apathy; Cognitive impairment; CT; Dementia; MRI; Neuropsychiatric symptoms; Vascular factors; White matter changes

Indexed keywords

ADULT; AGED; AGNOSIA; ALZHEIMER DISEASE; ANAMNESIS; APATHY; APHASIA; APRAXIA; ARTICLE; ATAXIA; BABINSKI REFLEX; BLOOD PRESSURE; CAROTID ARTERY OBSTRUCTION; CLINICAL EXAMINATION; COGNITION; COMPUTER ASSISTED TOMOGRAPHY; CONCENTRATION LOSS; CONTROLLED STUDY; DEPRESSION; DIABETES MELLITUS; DISEASE SEVERITY; DISORIENTATION; DYSARTHRIA; DYSPHAGIA; FEMALE; GAIT DISORDER; HALLUCINATION; HEART ARRHYTHMIA; HUMAN; HYPERTENSION; HYPOKINESIA; HYPOTENSION; INHIBITION (PSYCHOLOGY); INTERMITTENT CLAUDICATION; ISCHEMIC HEART DISEASE; JAW OPENING REFLEX; LABORATORY TEST; LANGUAGE DISABILITY; MAJOR CLINICAL STUDY; MALE; MEMORY DISORDER; MENTAL CAPACITY; MENTAL DISEASE; MILD COGNITIVE IMPAIRMENT; MIXED DEPRESSION AND DEMENTIA; MULTIINFARCT DEMENTIA; MYOCLONUS; NEUROLOGIC DISEASE; NUCLEAR MAGNETIC RESONANCE IMAGING; PARANOIA; RESTLESSNESS; RIGIDITY; STROKE; THOUGHT DISORDER; TRANSIENT ISCHEMIC ATTACK; TREMOR; WAKEFULNESS; WHITE MATTER;

EID: 77952414705     PISSN: 08856230     EISSN: 10991166     Source Type: Journal    
DOI: 10.1002/gps.2379     Document Type: Article
Times cited : (53)

References (43)
  • 1
    • 36448966462 scopus 로고    scopus 로고
    • Neuropsychiatric syndromes in dementia: Results from the European Alzheimer Disease Consortium. Part I
    • Aalten P, Verhey FR, Boziki M, et al. 2007. Neuropsychiatric syndromes in dementia: results from the European Alzheimer Disease Consortium. Part I. Dement Geriatr Cogn Disord 24: 457-463.
    • (2007) Dement Geriatr Cogn Disord , vol.24 , pp. 457-463
    • Aalten, P.1    Verhey, F.R.2    Boziki, M.3
  • 2
    • 37349024784 scopus 로고    scopus 로고
    • Consistency of neuropsychiatric syndromes across dementias: Results from the European Alzheimer Disease Consortium. Part II
    • Aalten P, Verhey FR, Boziki M, et al. 2008. Consistency of neuropsychiatric syndromes across dementias: results from the European Alzheimer Disease Consortium. Part II. Dement Geriatr Cogn Disord 25: 1-8.
    • (2008) Dement Geriatr Cogn Disord , vol.25 , pp. 1-8
    • Aalten, P.1    Verhey, F.R.2    Boziki, M.3
  • 3
    • 0004235298 scopus 로고
    • American Psychiatric Association. 3rd edn, revised. American Psychiatric Association: Washington, DC
    • American Psychiatric Association. 1987. Diagnostic and Statistical Manual of Mental Disorders, 3rd edn, revised. American Psychiatric Association: Washington, DC.
    • (1987) Diagnostic and Statistical Manual of Mental Disorders
  • 5
    • 41149085551 scopus 로고    scopus 로고
    • Association of gait and balance disorders with age-related white matter changes: The LADIS study
    • Baezner H, Blahak C, Poggesi A, et al. (2008). Association of gait and balance disorders with age-related white matter changes: the LADIS study. Neurology 70: 935-942.
    • (2008) Neurology , vol.70 , pp. 935-942
    • Baezner, H.1    Blahak, C.2    Poggesi, A.3
  • 6
    • 33748463827 scopus 로고    scopus 로고
    • Age, hypertension, and lacunar stroke are the major determinants of the severity of age-related white matter changes
    • The LADIS (Leukoaraiosis and Disability in the Elderly) Study
    • Basile AM, Pantoni L, Pracucci G, et al. 2006. Age, hypertension, and lacunar stroke are the major determinants of the severity of age-related white matter changes. The LADIS (Leukoaraiosis and Disability in the Elderly) Study. Cerebrovasc Dis 21: 315-322.
    • (2006) Cerebrovasc Dis , vol.21 , pp. 315-322
    • Basile, A.M.1    Pantoni, L.2    Pracucci, G.3
  • 7
    • 66149112915 scopus 로고    scopus 로고
    • Deep frontal and periventricular age-related white matter changes but not basal ganglia and infratentorial hyperintensities are associated with falls - Cross-sectional results from the LADIS study
    • Blahak C, Baezner H, Pantoni L, et al. (2009). Deep frontal and periventricular age-related white matter changes but not basal ganglia and infratentorial hyperintensities are associated with falls - cross-sectional results from the LADIS study. J Neurol Neurosurg Psychiatry 80: 608-613.
    • (2009) J Neurol Neurosurg Psychiatry , vol.80 , pp. 608-613
    • Blahak, C.1    Baezner, H.2    Pantoni, L.3
  • 8
    • 0025978236 scopus 로고
    • White-matter lesions on CT in Alzheimer patients: Relation to clinical symptomatology and vascular factors
    • Blennow K, Wallin A, Uhlemann C, Gottfries CG. 1991. White-matter lesions on CT in Alzheimer patients: relation to clinical symptomatology and vascular factors. Acta Neurol Scand 83: 187-193.
    • (1991) Acta Neurol Scand , vol.83 , pp. 187-193
    • Blennow, K.1    Wallin, A.2    Uhlemann, C.3    Gottfries, C.G.4
  • 9
    • 0034962978 scopus 로고    scopus 로고
    • Dementia due to subcortical ischemic vascular disease
    • Chui H. 2001. Dementia due to subcortical ischemic vascular disease. Clin Cornerstone 3: 40-51.
    • (2001) Clin Cornerstone , vol.3 , pp. 40-51
    • Chui, H.1
  • 10
    • 0028216732 scopus 로고
    • Vascular subcortical dementias: Clinical aspects
    • Cummings JL. 1994. Vascular subcortical dementias: clinical aspects. Dementia 5: 177-180.
    • (1994) Dementia , vol.5 , pp. 177-180
    • Cummings, J.L.1
  • 11
    • 0031866395 scopus 로고    scopus 로고
    • Neuropathology of white matter changes in Alzheimer's disease and vascular dementia
    • Englund E. 1998. Neuropathology of white matter changes in Alzheimer's disease and vascular dementia. Dement Geriatr CognDisord 9 (Suppl 1): 6-12. (Pubitemid 28325636)
    • (1998) Dementia and Geriatric Cognitive Disorders , vol.9 , Issue.SUPPL. 1 , pp. 6-12
    • Englund, E.1
  • 12
    • 0036128625 scopus 로고    scopus 로고
    • Neuropathology of white matter lesions in vascular cognitive impairment
    • DOI 10.1159/000049144
    • Englund E. 2002. Neuropathology of white matter lesions in vascular cognitive impairment. Cerebrovasc Dis 13 (Suppl 2): 11-15. (Pubitemid 34233903)
    • (2002) Cerebrovascular Diseases , vol.13 , Issue.SUPPL. 2 , pp. 11-15
    • Englund, E.1
  • 14
    • 0037111348 scopus 로고    scopus 로고
    • Age-related white matter changes and cognitive impairment
    • DOI 10.1016/S0022-510X(02)00295-2, PII S0022510X02002952
    • Ferro JM, Madureira S. 2002. Age-related white matter changes and cognitive impairment. J Neurol Sci 203-204: 221-225. (Pubitemid 35291190)
    • (2002) Journal of the Neurological Sciences , vol.203-204 , pp. 221-225
    • Ferro, J.M.1    Madureira, S.2
  • 15
    • 23644449403 scopus 로고    scopus 로고
    • White matter hyperintensities and depression-preliminary results from the LADIS study
    • Firbank MJ, O'Brien JT, Pakrasi S, et al. (2005). White matter hyperintensities and depression-preliminary results from the LADIS study. Int J Geriatr Psychiatry 20: 674-679.
    • (2005) Int J Geriatr Psychiatry , vol.20 , pp. 674-679
    • Firbank, M.J.1    O'Brien, J.T.2    Pakrasi, S.3
  • 16
    • 0016823810 scopus 로고
    • 'Mini-mental state'. A practical method for grading the cognitive state of patients for the clinician
    • Folstein MF, Folstein SE, Mchugh PR. 1975. 'Mini-mental state'. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12: 189-198.
    • (1975) J Psychiatr Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    Mchugh, P.R.3
  • 17
    • 44449143042 scopus 로고    scopus 로고
    • Progression of white matter hyperintensities and incidence of new lacunes over a 3-year period: The Leukoaraiosis and Disability study
    • Gouw AA, Van Der Flier WM, Fazekas F, et al. 2008. Progression of white matter hyperintensities and incidence of new lacunes over a 3-year period: the Leukoaraiosis and Disability study. Stroke 39: 1414-1420.
    • (2008) Stroke , vol.39 , pp. 1414-1420
    • Gouw, A.A.1    Van Der Flier, W.M.2    Fazekas, F.3
  • 18
    • 44449089581 scopus 로고    scopus 로고
    • Unrecognized myocardial infarction in relation to risk of dementia and cerebral small vessel disease
    • Ikram MA, Van Oijen M, De Jong FJ, et al. 2008. Unrecognized myocardial infarction in relation to risk of dementia and cerebral small vessel disease. Stroke 39: 1421-1426.
    • (2008) Stroke , vol.39 , pp. 1421-1426
    • Ikram, M.A.1    Van Oijen, M.2    De Jong, F.J.3
  • 19
    • 44649131215 scopus 로고    scopus 로고
    • Morphologic diagnosis of 'vascular dementia' - A critical update
    • Jellinger KA. 2008a. Morphologic diagnosis of 'vascular dementia' - a critical update. J Neurol Sci 270: 1-12.
    • (2008) J Neurol Sci , vol.270 , pp. 1-12
    • Jellinger, K.A.1
  • 20
    • 47849092520 scopus 로고    scopus 로고
    • The pathology of 'vascular dementia': A critical update
    • Jellinger KA. 2008b. The pathology of 'vascular dementia': a critical update. J Alzheimers Dis 14: 107-123.
    • (2008) J Alzheimers Dis , vol.14 , pp. 107-123
    • Jellinger, K.A.1
  • 21
    • 33750147881 scopus 로고    scopus 로고
    • Relationship between periventricular and deep white matter lesions and depressive symptoms in older people
    • The LADIS Study
    • Krishnan MS, O'Brien JT, Firbank MJ, et al. (2006). Relationship between periventricular and deep white matter lesions and depressive symptoms in older people. The LADIS Study. Int J Geriatr Psychiatry 21: 983-989.
    • (2006) Int J Geriatr Psychiatry , vol.21 , pp. 983-989
    • Krishnan, M.S.1    O'Brien, J.T.2    Firbank, M.J.3
  • 23
  • 24
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • Mckhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. 1984. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34: 939-944.
    • (1984) Neurology , vol.34 , pp. 939-944
    • Mckhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 25
    • 0036450036 scopus 로고    scopus 로고
    • Impact of subcortical ischemic lesions on behavior and cognition
    • Mori E. 2002. Impact of subcortical ischemic lesions on behavior and cognition. Ann N Y Acad Sci 977: 141-148.
    • (2002) Ann N Y Acad Sci , vol.977 , pp. 141-148
    • Mori, E.1
  • 26
    • 33749683310 scopus 로고    scopus 로고
    • White matter hyperintensities rather than lacunar infarcts are associated with depressive symptoms in older people: The LADIS study
    • O'brien JT, Firbank MJ, Krishnan MS, et al. 2006. White matter hyperintensities rather than lacunar infarcts are associated with depressive symptoms in older people: the LADIS study. Am J Geriatr Psychiatry 14: 834-841.
    • (2006) Am J Geriatr Psychiatry , vol.14 , pp. 834-841
    • O'brien, J.T.1    Firbank, M.J.2    Krishnan, M.S.3
  • 27
    • 0035195760 scopus 로고    scopus 로고
    • Current concepts in mild cognitive impairment
    • Petersen RC, Doody R, Kurz A, et al. 2001. Current concepts in mild cognitive impairment. Arch Neurol 58: 1985-1992.
    • (2001) Arch Neurol , vol.58 , pp. 1985-1992
    • Petersen, R.C.1    Doody, R.2    Kurz, A.3
  • 28
    • 33644795233 scopus 로고    scopus 로고
    • Vascular dementia prevention: A risk factor analysis
    • Roman GC. 2005. Vascular dementia prevention: a risk factor analysis. Cerebrovasc Dis 20 (Suppl 2): 91-100.
    • (2005) Cerebrovasc Dis , vol.20 , Issue.SUPPL. 2 , pp. 91-100
    • Roman, G.C.1
  • 29
    • 33750022878 scopus 로고    scopus 로고
    • Vascular determinants of cholinergic deficits in Alzheimer disease and vascular dementia
    • Roman GC, Kalaria RN. 2006. Vascular determinants of cholinergic deficits in Alzheimer disease and vascular dementia. Neurobiol Aging 27: 1769-1785.
    • (2006) Neurobiol Aging , vol.27 , pp. 1769-1785
    • Roman, G.C.1    Kalaria, R.N.2
  • 31
    • 0027534657 scopus 로고
    • Vascular dementia: Diagnostic criteria for research studies. Report of the NINDS-AIREN International Workshop
    • Roman GC, Tatemichi TK, Erkinjuntti T, et al. 1993. Vascular dementia: diagnostic criteria for research studies. Report of the NINDS-AIREN International Workshop. Neurology 43: 250-260.
    • (1993) Neurology , vol.43 , pp. 250-260
    • Roman, G.C.1    Tatemichi, T.K.2    Erkinjuntti, T.3
  • 32
    • 43549094981 scopus 로고    scopus 로고
    • Imaging of mild cognitive impairment and early dementia
    • Schuff N, Zhu XP. 2007. Imaging of mild cognitive impairment and early dementia. Br J Radiol 80 (Spec No 2): S109-S114.
    • (2007) Br J Radiol , vol.80 , Issue.SPEC NO 2
    • Schuff, N.1    Zhu, X.P.2
  • 33
    • 0035499941 scopus 로고    scopus 로고
    • Neurofilament protein in cerebrospinal fluid: A marker of white matter changes
    • Sjogren M, Blomberg M, Jonsson M, et al. 2001. Neurofilament protein in cerebrospinal fluid: a marker of white matter changes. J Neurosci Res 66: 510-516.
    • (2001) J Neurosci Res , vol.66 , pp. 510-516
    • Sjogren, M.1    Blomberg, M.2    Jonsson, M.3
  • 35
    • 0034099258 scopus 로고    scopus 로고
    • Apathy and depression following stroke
    • Starkstein SE, Manes F. 2000. Apathy and depression following stroke. CNS Spectr 5: 43-50.
    • (2000) CNS Spectr , vol.5 , pp. 43-50
    • Starkstein, S.E.1    Manes, F.2
  • 36
    • 36849030286 scopus 로고    scopus 로고
    • Differential impact of cerebral white matter changes, diabetes, hypertension and stroke on cognitive performance among non-disabled elderly
    • The LADIS study
    • Verdelho A, Madureira S, Ferro JM, et al. (2007). Differential impact of cerebral white matter changes, diabetes, hypertension and stroke on cognitive performance among non-disabled elderly. The LADIS study. J Neurol Neurosurg Psychiatry 78: 1325-1330.
    • (2007) J Neurol Neurosurg Psychiatry , vol.78 , pp. 1325-1330
    • Verdelho, A.1    Madureira, S.2    Ferro, J.M.3
  • 37
    • 0031814840 scopus 로고    scopus 로고
    • The overlap between Alzheimer's disease and vascular dementia: The role of white matter changes
    • Wallin A. 1998. The overlap between Alzheimer's disease and vascular dementia: the role of white matter changes. Dement Geriatr Cogn Disord 9 (Suppl 1): 30-35.
    • (1998) Dement Geriatr Cogn Disord , vol.9 , Issue.SUPPL. 1 , pp. 30-35
    • Wallin, A.1
  • 38
    • 0028216734 scopus 로고
    • The clinical diagnosis of vascular dementia
    • Wallin A, Blennow K. 1994. The clinical diagnosis of vascular dementia. Dementia 5: 181-184.
    • (1994) Dementia , vol.5 , pp. 181-184
    • Wallin, A.1    Blennow, K.2
  • 39
    • 0024817784 scopus 로고
    • White matter low attenuation on computed tomography in Alzheimer's disease and vascular dementia-diagnostic and pathogenetic aspects
    • Wallin A, Blennow K, Uhlemann C, Langstrom G, Gottfries CG. 1989. White matter low attenuation on computed tomography in Alzheimer's disease and vascular dementia-diagnostic and pathogenetic aspects. Acta Neurol Scand 80: 518-523.
    • (1989) Acta Neurol Scand , vol.80 , pp. 518-523
    • Wallin, A.1    Blennow, K.2    Uhlemann, C.3    Langstrom, G.4    Gottfries, C.G.5
  • 40
    • 0030447084 scopus 로고    scopus 로고
    • Stepwise comparative status analysis (STEP): A tool for identification of regional brain syndromes in dementia
    • Wallin A, Edman A, Blennow K, et al. 1996. Stepwise comparative status analysis (STEP): a tool for identification of regional brain syndromes in dementia. J Geriatr Psychiatry Neurol 9: 185-199.
    • (1996) J Geriatr Psychiatry Neurol , vol.9 , pp. 185-199
    • Wallin, A.1    Edman, A.2    Blennow, K.3
  • 41
    • 0033679258 scopus 로고    scopus 로고
    • Symptoms, vascular risk factors and blood-brain barrier function in relation to CT white-matter changes in dementia
    • Wallin A, Sjogren M, Edman A, Blennow K, Regland B. 2000. Symptoms, vascular risk factors and blood-brain barrier function in relation to CT white-matter changes in dementia. Eur Neurol 44: 229-235.
    • (2000) Eur Neurol , vol.44 , pp. 229-235
    • Wallin, A.1    Sjogren, M.2    Edman, A.3    Blennow, K.4    Regland, B.5
  • 43
    • 4544350756 scopus 로고    scopus 로고
    • Mild cognitive impairment-beyond controversies, towards a consensus: Report of the International Working Group on Mild Cognitive Impairment
    • Winblad B, Palmer K, Kivipelto M, et al. 2004. Mild cognitive impairment-beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment. J Intern Med 256: 240-246.
    • (2004) J Intern Med , vol.256 , pp. 240-246
    • Winblad, B.1    Palmer, K.2    Kivipelto, M.3


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