Serum ceruloplasmin and copper are early biomarkers for traumatic brain injury-associated elevated intracranial pressure

Journal of Neuroscience Research

Volumn 88, Issue 8, 2010, Pages 1719-1726

  Dash, Pramod K ^a   Redell, John B ^a   Hergenroeder, Georgene ^a   Zhao, Jing ^a   Clifton, Guy L ^a   Moore, Anthony ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Biomarker; Brain swelling; Brain trauma; Iron oxidase; Plasma

Indexed keywords

BIOLOGICAL MARKER; CERULOPLASMIN; COPPER;

ADOLESCENT; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; COPPER BLOOD LEVEL; FEMALE; HUMAN; INTRACRANIAL PRESSURE; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY;

ADOLESCENT; ADULT; AGED; ANALYSIS OF VARIANCE; BIOLOGICAL MARKERS; BRAIN INJURIES; CERULOPLASMIN; COPPER; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; INTRACRANIAL HYPERTENSION; MALE; MIDDLE AGED; TIME FACTORS; YOUNG ADULT;

EID: 77952407569     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22336     Document Type: Article

References (43)

1. Abe A, Yamashita S, Noma A. 1989. Sensitive, direct colorimetric assay for copper in serum. Clin Chem 35:552-554. (Pubitemid 19111064)
2. Braakman R, Gelpke GJ, Habbema JD, Maas AI, Minderhoud JM. 1980. Systematic selection of prognostic features in patients with severe head injury. Neurosurgery 6:362-370. (Pubitemid 10102601)
3. Bramlett HM, Dietrich WD. 2007. Progressive damage after brain and spinal cord injury: pathomechanisms and treatment strategies. Prog Brain Res 161:125-141.
4. Bullock R. 1995. Mannitol and other diuretics in severe neurotrauma. New Horiz 3:448-452.
5. Chan PH, Epstein CJ, Li Y, Huang TT, Carlson E, Kinouchi H, Yang G, Kamii H, Mikawa S, Kondo T. 1995. Transgenic mice and knockout mutants in the study of oxidative stress in brain injury. J Neurotrauma 12:815-824.
6. Choi SC, Muizelaar JP, Barnes TY, Marmarou A, Brooks DM, Young HF. 1991. Prediction tree for severely head-injured patients. J Neurosurg 75:251-255.
7. Choi SY, Kwon HY, Kwon OB, Eum WS, Kang JH. 2000. Fragmentation of human ceruloplasmin induced by hydrogen peroxide. Biochimie 82:175-180. (Pubitemid 30153556)
8. Das SK, Ray K. 2006. Wilson's disease: an update. Nat Clin Pract Neurol 2:482-493.
9. Gitlin D, Janeway CA. 1960. Turnover of the copper and protein moieties of ceruloplasmin. Nature 185:693.
10. Goldstein IM, Kaplan HB, Edelson HS, Weissmann G. 1982. Ceruloplasmin: an acute phase reactant that scavenges oxygen-derived free radicals. Ann N Y Acad Sci 389:368-379. (Pubitemid 12013202)
11. Hellman NE, Gitlin JD. 2002. Ceruloplasmin metabolism and function. Annu Rev Nutr 22:439-458.
12. Hergenroeder G, Redell JB, Moore AN, Dubinsky WP, Funk RT, Crommett J, Clifton GL, Levine R, Valadka A, Dash PK. 2008. Identification of serum biomarkers in brain-injured adults: potential for predicting elevated intracranial pressure. J Neurotrauma 25:79-93. (Pubitemid 351252579)
13. Hlatky R, Valadka AB, Robertson CS. 2003. Intracranial hypertension and cerebral ischemia after severe traumatic brain injury. Neurosurg Focus 14:e2.
14. Hoffman RM, Gilliland FD, Adams-Cameron M, Hunt WC, Key CR. 2002. Prostate-specific antigen testing accuracy in community practice. BMC Fam Pract 3:19. (Pubitemid 38994222)
15. Incerti J, Zelmanovitz T, Camargo JL, Gross JL, de Azevedo MJ. 2005. Evaluation of tests for microalbuminuria screening in patients with diabetes. Nephrol Dial Transplant 20:2402-2407. (Pubitemid 41548863)
16. Kang JH, Kim KS, Choi SY, Kwon HY, Won MH. 2001. Oxidative modification of human ceruloplasmin by peroxyl radicals. Biochim Biophys Acta 1568:30-36. (Pubitemid 33145381)
17. Knaus WA, Draper EA, Wagner DP, Zimmerman JE. 1985. APACHE II: a severity of disease classification system. Crit Care Med 13:818-829. (Pubitemid 15250137)
18. Kuhlow CJ, Krady JK, Basu A, Levison SW. 2003. Astrocytic ceruloplasmin expression, which is induced by IL-1beta and by traumatic brain injury, increases in the absence of the IL-1 type 1 receptor. Glia 44:76-84. (Pubitemid 37176322)
19. Marmarou A. 1992. Increased intracranial pressure in head injury and influence of blood volume. J Neurotrauma 9(Suppl 1):S327-S332.
20. Marrero JA, Feng Z, Wang Y, Nguyen MH, Befeler AS, Roberts LR, Reddy KR, Harnois D, Llovet JM, Normolle D, Dalhgren J, Chia D, Lok AS, Wagner PD, Srivastava S, Schwartz M. 2009. Alpha-fetoprotein, des-gamma carboxyprothrombin, and lectin-bound alpha-fetoprotein in early hepatocellular carcinoma. Gastroenterology 137:110-118.
21. Medeiros LR, Rosa DD, da Rosa MI, Bozzetti MC. 2009. Accuracy of CA 125 in the diagnosis of ovarian tumors: a quantitative systematic review. Eur J Obstet Gynecol Reprod Biol 142:99-105.
22. Menkes JH. 1988. Kinky hair disease: twenty five years later. Brain Dev 10:77-79.
23. Nussier MK, Ababneh BM. 2006. Diagnostic efficiency of creatine kinase (CK), CKMB, tropinin T and troponin I in patients with suspected acute myocardial infarction. J Health Sci 52:180-185.
24. O'Connor TP, Bentley D. 1993. Accumulation of actin in subsets of pioneer growth cone filopodia in response to neural and epithelial guidance cues in situ. J Cell Biol 123:935-948. (Pubitemid 23333581)
25. Oertel M, Kelly DF, Lee JH, McArthur DL, Glenn TC, Vespa P, Boscardin WJ, Hovda DA, Martin NA. 2002. Efficacy of hyperventilation, blood pressure elevation, and metabolic suppression therapy in controlling intracranial pressure after head injury. J Neurosurg 97:1045-1053. (Pubitemid 35253540)
26. Petzold A, Green AJ, Keir G, Fairley S, Kitchen N, Smith M, Thompson EJ. 2002. Role of serum S100B as an early predictor of high intracranial pressure and mortality in brain injury: a pilot study. Crit Care Med 30:2705-2710. (Pubitemid 36870573)
27. Povlishock JT. 2000. Pathophysiology of neural injury: therapeutic opportunities and challenges. Clin Neurosurg 46:113-126.
28. Raghupathi R. 2004. Cell death mechanisms following traumatic brain injury. Brain Pathol 14:215-222. (Pubitemid 38656395)
29. Ray SK, Dixon CE, Banik NL. 2002. Molecular mechanisms in the pathogenesis of traumatic brain injury. Histol Histopathol 17:1137-1152.
30. Rebhun J, Madorsky JG, Glovsky MM. 1991. Proteins of the complement system and acute phase reactants in sera of patients with spinal cord injury. Ann Allerg 66:335-338.
31. Reichlin T, Hochholzer W, Bassetti S, Steuer S, Stelzig C, Hartwiger S, Biedert S, Schaub N, Buerge C, Potocki M, Noveanu M, Breidthardt T, Twerenbold R, Winkler K, Bingisser R, Mueller C. 2009. Early diagnosis of myocardial infarction with sensitive cardiac troponin assays. N Engl J Med 361:858-867.
32. Shore PM, Berger RP, Varma S, Janesko KL, Wisniewski SR, Clark RS, Adelson PD, Thomas NJ, Lai YC, Bayir H, Kochanek PM. 2007. Cerebrospinal fluid biomarkers vs. glasgow coma scale and glasgow outcome scale in pediatric traumatic brain injury: the role of young age and inflicted injury. J Neurotrauma 24:75-86. (Pubitemid 46214413)
33. Teasdale G, Jennett B. 1974. Assessment of coma and impaired consciousness. A practical scale. Lancet 2:81-84.
34. Tomas E, Toparceanu F. 1986. Considerations about the possible function of ceruloplasmin in influenza and parainfluenza virus infections. Virologie 37:279-287.
35. Vassiliev V, Harris ZL, Zatta P. 2005. Ceruloplasmin in neurodegenerative diseases. Brain Res Brain Res Rev 49:633-640.
36. Wang KK, Ottens AK, Liu MC, Lewis SB, Meegan C, Oli MW, Tortella FC, Hayes RL. 2005. Proteomic identification of biomarkers of traumatic brain injury. Expert Rev Proteomics 2:603-614. (Pubitemid 41139842)
37. Wang X, Rousset CI, Hagberg H, Mallard C. 2006. Lipopolysaccharide- induced inflammation and perinatal brain injury. Semin Fetal Neonatal Med 11:343-353. (Pubitemid 44038704)
38. Ware ML, Nemani VM, Meeker M, Lee C, Morabito DJ, Manley GT. 2005. Effects of 23.4% sodium chloride solution in reducing intracranial pressure in patients with traumatic brain injury: a preliminary study. Neurosurgery 57:727-736.
39. Xu X, Pin S, Gathinji M, Fuchs R, Harris ZL. 2004. Aceruloplasminemia: an inherited neurodegenerative disease with impairment of iron homeostasis. Ann N Y Acad Sci 1012:299-305. (Pubitemid 38453533)
40. Young AB, Ott LG, Beard D, Dempsey RJ, Tibbs PA, McClain CJ. 1988. The acute-phase response of the brain-injured patient. J Neurosurg 69:375-380.
41. Zemlan FP, Jauch EC, Mulchahey JJ, Gabbita SP, Rosenberg WS, Speciale SG, Zuccarello M. 2002. C-tau biomarker of neuronal damage in severe brain injured patients: association with elevated intracranial pressure and clinical outcome. Brain Res 947:131-139. (Pubitemid 34876523)
42. Zhao J, Moore AN, Redell JB, Dash PK. 2007. Enhancing expression of Nrf2-driven genes protects the blood brain barrier after brain injury. J Neurosci 27:10240-10248. (Pubitemid 47450456)
43. Zweig MH, Campbell G. 1993. Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine. Clin Chem 39:561-577. (Pubitemid 23118304)