Probing the "charge cluster mechanism" in amphipathic helical cationic antimicrobial peptides

Biochemistry

Volumn 49, Issue 19, 2010, Pages 4076-4084

  Epand, Raquel F ^a   Maloy, W Lee ^b   Ramamoorthy, Ayyalusamy ^c   Epand, Richard M ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b Genaera Pharmaceuticals   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHIPATHIC; ANIONIC CHARGE; ANIONIC LIPIDS; ANTI-MICROBIAL AGENT; ANTIMICROBIAL PEPTIDE; CATIONIC ANTIMICROBIAL PEPTIDES; CHARGE CLUSTERS; CYTOPLASMIC MEMBRANE; E. COLI; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIUM; LOWER DENSITY; MAGAININ; MECHANISM OF ACTION; N-TERMINALS; POSITIVE CHARGES; S. AUREUS; STAPHYLOCOCCUS AUREUS; SYNTHETIC PEPTIDE; TOXIC ACTION;

BACTERIA; BACTERIOLOGY; CELL MEMBRANES; ESCHERICHIA COLI; LIPIDS; PEPTIDES; POLYPEPTIDES; TOXICITY;

DYES;

AMPHOLYTE; ANTIINFECTIVE AGENT; MAGAININ 2; MSI 103; MSI 1254; MSI 469; MSI 843; PEXIGANAN ACETATE; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANTIMICROBIAL ACTIVITY; ARTICLE; CELL MEMBRANE; ESCHERICHIA COLI; GRAM POSITIVE BACTERIUM; NONHUMAN; PRIORITY JOURNAL; SPECIES DIFFERENCE; STAPHYLOCOCCUS AUREUS;

ANTIMICROBIAL CATIONIC PEPTIDES; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; ESCHERICHIA COLI; PEPTIDES; STAPHYLOCOCCUS AUREUS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA; POSIBACTERIA; STAPHYLOCOCCUS AUREUS;

EID: 77952395366     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi100378m     Document Type: Article

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