Topological criteria to safely optimize hazardous chemical processes involving consecutive reactions

Industrial and Engineering Chemistry Research

Volumn 49, Issue 10, 2010, Pages 4583-4593

  Copelli, Sabrina ^a   Derudi, Marco ^a   Rota, Renato ^a  

^a POLITECNICO DI MILANO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL SYSTEMS; COMPLEX INTERACTION; CONSECUTIVE REACTION; EXPERIMENTAL DATA; HAZARDOUS CHEMICALS; OPERATING PARAMETERS; OPERATING REGIONS; OPTIMIZATION PROCEDURES; OPTIMUM VALUE; PHASE SPACES; REACTOR TEMPERATURES; SAFE OPERATING CONDITIONS; SAFETY CONSTRAINT; SEMI-BATCH PROCESS; SYSTEM OF ORDINARY DIFFERENTIAL EQUATIONS; TEMPERATURE PROFILES; TOPOLOGICAL ANALYSIS; TOPOLOGICAL CRITERIA;

OPTIMIZATION; PHASE SPACE METHODS; TOPOLOGY;

ORDINARY DIFFERENTIAL EQUATIONS;

EID: 77952346765     PISSN: 08885885     EISSN: 15205045     Source Type: Journal    
DOI: 10.1021/ie901679q     Document Type: Article

References (19)

1. Varma, A., Morbidelli, M., and Wu, H. Parametric Sensitivity in Chemical Systems; Cambridge University Press: Cambridge, U.K., 1999.
2. Strozzi, F.; Zaldívar, J. M.; Kronberg, A. E.; Westerterp, K. R. On-line runaway detection in batch reactors using chaos theory techniques AIChE J. 1999, 45, 2429
3. Zaldívar, J. M.; Cano, J.; Alós, M. A.; Sempere, J. M.; Nomen, R.; Lister, D.; Maschio, G.; Obertopp, T.; Gilles, E. D.; Bosch, J.; Strozzi, F. A general criterion to define runaway limits in chemical reactors J. Loss Prev. Process Ind. 2003, 16, 187
4. Bosch, J.; Strozzi, F.; Zbilut, J. P.; Zaldívar, J. M. On-line runaway detection in isoperibolic batch and semibatch reactors using the divergence criterion Comput. Chem. Eng. 2004, 28, 527
5. Zaldívar, J. M.; Bosch, J.; Strozzi, F.; Zbilut, J. P. Early Warning detection of runaway initiation using non-linear approaches Int. J. Nonlinear Sci. Numer. Simul. 2005, 10, 299
6. Hugo, P.; Steinbach, J. Praxisorientierte Darstellung der thermischen Sicherheitsgrenzen fuür den indirekt gekuühlten Semibatch-Reaktor Chem. Ing. Tech. 1985, 57, 780
7. Steensma, M.; Westerterp, K. R. Thermally safe operation of a cooled semi-batch reactor. Slow liquid-liquid reactions Chem. Eng. Sci. 1988, 43, 2125
8. Steensma, M.; Westerterp, K. R. Thermally safe operation of a semibatch reactor for liquid-liquid reactions. Slow reactions Ind. Eng. Chem. Res. 1990, 29, 1259
9. Steensma, M.; Westerterp, K. R. Thermally safe operation of a semibatch reactor for liquid-liquid reactions. Fast reactions Chem. Eng. Technol. 1991, 14, 367
10. Alós, M. A.; Nomen, R.; Sempere, J. M.; Strozzi, F.; Zaldívar, J. M. Generalized criteria for boundary safe conditions in semi-batch processes: Simulated analysis and experimental results Chem. Eng. Process. 1998, 37, 405
11. Maestri, F.; Rota, R. Temperature diagrams for preventing decomposition or side reactions in liquid-liquid semibatch reactors Chem. Eng. Sci. 2006, 61, 3068
12. Maestri, F.; Copelli, S.; Rota, R.; Gigante, L.; Lunghi, A.; Cardillo, P. Simple procedure for optimally scaling-up fine chemical processes. I. Practical tools Ind. Eng. Chem. Res. 2009, 48, 1307
13. Maestri, F.; Copelli, S.; Rota, R.; Gigante, L.; Lunghi, A.; Cardillo, P. Simple procedure for optimal scale-up of fine chemical processes. II. Nitration of 4-chlorobenzotrifluoride Ind. Eng. Chem. Res. 2009, 48, 1316
14. Maestri, F.; Rota, R. Thermally safe operation of liquid-liquid semibatch reactors. Part I: Single kinetically controlled reactions with arbitrary reaction order Chem. Eng. Sci. 2005, 60, 3309
15. Maestri, F.; Rota, R. Thermally safe operation of liquid-liquid semibatch reactors. Part II: Single diffusion controlled reactions with arbitrary reaction order Chem. Eng. Sci. 2005, 60, 5590
16. van Woezik, B. A. A.; Westerterp, K. R. The nitric acid oxidation of 2-octanol. A model reaction for multiple heterogeneous liquid-liquid reactions Chem. Eng. Process. 2000, 39, 521
17. van Woezik, B. A. A.; Westerterp, K. R. Runaway behaviour and thermally safe operation of multiple liquid-liquid reactions in the semibatch reactor. The nitric acid oxidation of 2-octanol Chem. Eng. Process. 2001, 41, 59
18. Copelli, S.; Derudi, M.; Maestri, F.; Rota, R. Safe operating conditions for semibatch processes involving consecutive reactions with autocatalytic behaviour. Submitted to Chem. Eng. Sci., 2009.
19. Steinbach, J. Safety Assessment for Chemical Processes; Wiley-VCH Verlag GmbH: Weinheim, Germany, 1999.