Development of a high-throughput method for the determination of ethosuximide in human plasma by liquid chromatography mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 878, Issue 19, 2010, Pages 1605-1610

  Bhatt, Mitesh ^a,b   Shah, Sanjay ^a   Shivprakash, ^b  

^a SmtMGPanchal Science and VLShah Commerce College Pilvai   (India)

^b Synchron Research Services Private Limited   (India)

Author keywords

Acquity UPLC; Ethosuximide; Human plasma; LC MS MS

Indexed keywords

ACQUITY; ANALYSIS TIME; ANALYTES; CONCENTRATION RANGES; ETHOSUXIMIDE; HIGH-THROUGHPUT METHOD; HUMAN PLASMAS; INTERNAL STANDARDS; ISOCRATIC ELUTION; LC-MS/MS; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; LOWER LIMIT OF QUANTIFICATIONS; PRAVASTATIN; QUADRUPOLES; SOLID-PHASE EXTRACTION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; UPLC-MS/MS;

CUSTOMER SATISFACTION; ELECTROSPRAY IONIZATION; EXTRACTION; LIQUIDS; MASS SPECTROMETRY; PLASMA (HUMAN); PLASMAS; QUALITY CONTROL; TOTAL QUALITY MANAGEMENT;

LIQUID CHROMATOGRAPHY;

ETHOSUXIMIDE; PRAVASTATIN;

ACCURACY; ANALYTIC METHOD; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG STABILITY; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; ELUTION; FLOW RATE; FREEZE THAWING; HUMAN; PRIORITY JOURNAL; QUADRUPOLE MASS SPECTROMETRY; QUANTITATIVE ASSAY; SOLID PHASE EXTRACTION; STORAGE TEMPERATURE; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; VALIDATION PROCESS;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; ETHOSUXIMIDE; HUMANS; LEAST-SQUARES ANALYSIS; PRAVASTATIN; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SOLID PHASE MICROEXTRACTION; TANDEM MASS SPECTROMETRY;

EID: 77952321714     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2010.03.019     Document Type: Article

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