Anti-fatigue effect of dicethiamine hydrochloride is likely associated with excellent absorbability and high transformability in tissues as a vitamin B1

European Journal of Pharmacology

Volumn 635, Issue 1-3, 2010, Pages 117-123

  Shimizu, Toshikatsu ^a   Hoshino, Hiroshi ^a   Nishi, Shugo ^a   Nozaki, Satoshi ^b   Watanabe, Yasuyoshi ^b,c  

^a SHIONOGI AND CO LTD   (Japan)

^b RIKEN   (Japan)

^c OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Absorption; Dicethiamine; Fatigue; Thiamine; Tissue distribution

Indexed keywords

CETOTIAMINE; THIAMINE; THIAMINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CEREBELLUM; CONTROLLED STUDY; DOSE RESPONSE; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG MEGADOSE; DRUG TISSUE LEVEL; DRUG TRANSFORMATION; FATIGUE; HEART; HIPPOCAMPUS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; THIGH; TISSUE DISTRIBUTION;

ABSORPTION; ADMINISTRATION, ORAL; ANIMALS; FATIGUE; MALE; PYRIMIDINES; RATS; RATS, SPRAGUE-DAWLEY; THIAMINE; TIME FACTORS;

EID: 77952321264     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.02.053     Document Type: Article

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