Preventive effects of low molecular mass potassium alginate extracted from brown algae on DOCA salt-induced hypertension in rats

Biomedicine and Pharmacotherapy

Volumn 64, Issue 4, 2010, Pages 291-295

  Chen, Yu Yun ^a   Ji, Wei ^a   Du, Jun Rong ^a   Yu, Dong Ke ^a   He, Yao ^a   Yu, Chuan Xing ^b   Li, De Shan ^b   Zhao, Chang yi ^b   Qiao, Kui yun ^b  

^a SICHUAN UNIVERSITY   (China)

^b Dalian Yaweite Bioengineering Company   (China)

Author keywords

DOCA salt; Hypertension; Hypokalemia; Potassium alginate; Potassium supplementation; Sodium excretion

Indexed keywords

ALGINATE POTASSIUM; ATRIAL NATRIURETIC FACTOR; DEOXYCORTICOSTERONE ACETATE; POLYSACCHARIDE; POTASSIUM CHLORIDE; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ALDOSTERONE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BROWN ALGA; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; HEART WEIGHT; HYPERTENSION; HYPOKALEMIA; KIDNEY MASS; MALE; MOLECULAR WEIGHT; MORNING DOSAGE; MORTALITY; NONHUMAN; PLASMA VOLUME; POTASSIUM BLOOD LEVEL; PRIMARY PREVENTION; PRIORITY JOURNAL; RAT; SODIUM BLOOD LEVEL; SODIUM EXCRETION; SYSTOLIC BLOOD PRESSURE;

ALGAE, BROWN; ALGINATES; ANIMALS; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; DESOXYCORTICOSTERONE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCURONIC ACID; HEXURONIC ACIDS; HYPERTENSION; MALE; POTASSIUM; POTASSIUM CHLORIDE; RATS; RATS, SPRAGUE-DAWLEY; SODIUM;

EID: 77952321241     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopha.2009.09.004     Document Type: Article

References (28)

1. Kearney P.M., Whelton M., Reynolds K., Muntner P., Whelton P.K., He J. Global burden of hypertension: analysis of worldwide data. Lancet 2005, 365:217-223.
2. Adrogué H.J., Madias N.E. Sodium and potassium in the pathogenesis of hypertension. N Engl J Med 2007, 356:1966-1978.
3. Weinberger M.H. Salt sensitivity of blood pressure in humans. Hypertension 1996, 27:481-490.
4. Weinberger M.H., Fineberg N.S., Fineberg S.E., Weinberger M. Salt sensitivity, pulse pressure, and death in normal and hypertensive humans. Hypertension 2001, 37:429-432.
5. Khaw K.T., Barrett-Connor E. Dietary potassium and stroke-associated mortality: a 12-year prospective population study. N Engl J Med 1987, 316:235-240.
6. Villamil M.F., Deland E.C., Henney R.P., Maloney J.V. Anion effects on cation movements during correction of potassium depletion. Am J Physiol 1975, 29:161-166.
7. Novaczek I., Athy A. Sea vegetable recipes for the Pacific Islands. A guide to the common edible and medicinal sea plants of the Pacific Islands [USP Marine Studies Programme/SPC Coastal Fisheries Programme: Training Materials for Pacific Community Fisheries] 2001, University of the South Pacific, Secretariat of Pacific Community, Fiji.
8. Kawada A., Hiura N., Shiraiwa M., Tajima S., Hiruma M., Hara K., et al. Stimulation of human keratinocyte growth by alginate oligosaccharides, a possible co-factor for epidermal growth factor in cell culture. FEBS Lett 1997, 408:43-46.
9. Kawada A., Hiura N., Tajima S., Takahara H. Alginate oligosaccharides stimulate VEGF-mediated growth and migration of human endothelial cells. Arch Dermatol Res 1999, 291:542-547.
10. Queiroz K.C., Medeiros V.P., Queiroz L.S., Abreu L.R., Rocha H.A., Ferreira C.V., et al. Inhibition of reverse transcriptase activity of HIV by polysaccharides of brown algae. Biomed Pharmacother 2008, 62:303-307.
11. Ji W., Chen Y.Y., Du J.R., Yu D.K., Zheng X.Y., Yang F., et al. Antihypertensive effect and pharmacokinetics of low molecular mass potassium alginate. J Sichuan University (Medical Science Edition) 2009, 40:694-696.
12. Donati I., Gamini A., Skjak-Braek G., Vetere A., Campa C., Coslovi A., et al. Determination of the diadic composition of alginate by means of circular dichroism: a fast and accurate improved method. Carbohydr Res 2003, 338:1139-1142.
13. Lahlou S., Carneiro-Leão R.F.L., Leal-Cardoso J.H. Cardiovascular effects of the essential oil of Mentha×villosa in DOCA-salt-hypertensive rats. Phytomedicine 2002, 9:715-720.
14. Maeda K., Orita M., Hirano H., Higashino H. The effect of Kampo medicines (Gorei-san or Sairei-to) on DOCA-salt hypertension rat. J Trad Med 2003, 20:74-81.
15. Mulrow P.J., Forman B.H. The tissue effects of mineralocorticoids. Am J Med 1972, 53:561-572.
16. Young M., Fullerton M., Dilley R., Funder J. Mineralocorticoids, hypertension, and cardiac fibrosis. J Clin Invest 1994, 93:2578-2583.
17. Ellis D., Banner B., Janosky J.E., Feig P.U. Potassium supplementation attenuates experimental hypertensive renal injury. J Am Soc Nephrol 1992, 2:1529-1537.
18. Dolson G.M., Ellis K.J., Bernardo M.V., Prakash R., Adrogué H.J. Acute decreases in serum potassium augment blood pressure. Am J Kidney Dis 1995, 26:321-326.
19. Meneely G.R., Ball C.O. Experimental epidemiology of chronic sodium chloride toxicity and the protective effect of potassium chloride. Am J Med 1958, 25:713-725.
20. Suzuki H., Kondo K., Saruta T. Effect of potassium chloride on the blood pressure in two-kidney, one clip Goldblatt hypertensive rats. Hypertension 1981, 3:566-573.
21. Volpe M., Camargo M.J., Mueller F.B., Campbell W.G., Sealey J.E., Pecker M.S., et al. Relation of plasma renin to end organ damage and to protection of K+ feeding in stroke-prone hypertensive rats. Hypertension 1990, 15:318-326.
22. Manger W.M., Simchon S., Stier C.T., Loscalzo J., Jan K.M., Jan R., et al. Protective effects of dietary potassium chloride on hemodynamics of Dahl salt-sensitive rats in response to chronic administration of sodium chloride. J Hypertens 2003, 21:2305-2313.
23. Dolson G.M., Wesson D.E., Adrogue H.J. Vascular relaxation probably mediates the antihypertensive effect of a high-potassium diet: a role for enhanced vascular Na, K-ATPase activity. J Hypertens 1995, 13:1433-1439.
24. Cress L.W., Freas W., Haddy F., Muldoon S.M. Effects of bufalin on norepinephrine turnover in canine saphenous vein. Hypertension 1991, 18:516-522.
25. Fujita T., Sato Y. Changes in renal and central noradrenergic activity with potassium in DOCA-salt rats. Am J Physiol 1984, 246:F670-F675.
26. +) on the secretion of aldosterone. Endocrinology 1969, 85:381-384.
27. Valdes G., Bio C.P., Montero J., Avendano R. Potassium supplementation lowers blood pressure and increases urinary kallikrein in essential hypertensives. J Hum Hypertens 1991, 5:91-96.
28. Morris R.C., Sebastian A., Forman A., Tanaka M., Schmidlin O. Normotensive salt sensitivity: effects of race and dietary potassium. Hypertension 1999, 33:18-23.