Mammalian target of rapamycin (mTOR) is involved in the survival of cells mediated by chemokine receptor 7 through PI3K/Akt in metastatic squamous cell carcinoma of the head and neck

British Journal of Oral and Maxillofacial Surgery

Volumn 48, Issue 4, 2010, Pages 291-296

  Liu, Fa Yu ^a   Zhao, Zhen Jin ^a   Li, Peng ^a   Ding, Xue ^a   Zong, Zhi Hong ^a   Sun, Chang Fu ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

CCR7; mTOR; PI3K; Squamous cell carcinoma of head and neck; Survival

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CHEMOKINE RECEPTOR CCR7; CISPLATIN; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; RAPAMYCIN; S6 KINASE;

APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL DEATH; CELL INVASION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; FLOW CYTOMETRY; HEAD AND NECK CARCINOMA; HUMAN; HUMAN CELL; METASTASIS POTENTIAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CELL CYCLE; CELL DEATH; CELL LINE, TUMOR; CELL SURVIVAL; CHEMOKINE CCL19; CHROMONES; CISPLATIN; COLORING AGENTS; ENZYME INHIBITORS; FLOW CYTOMETRY; HEAD AND NECK NEOPLASMS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MORPHOLINES; NEOPLASM INVASIVENESS; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, CCR7; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIROLIMUS; TETRAZOLIUM SALTS; THIAZOLES;

EID: 77952320737     PISSN: 02664356     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bjoms.2009.06.007     Document Type: Article

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