Neurochemical and behavioral effects elicited by bupropion and diethylpropion in rats

Behavioural Brain Research

Volumn 211, Issue 1, 2010, Pages 132-139

  Santamaría, Abel ^a   Arias, Hugo R ^b  

^a NATIONAL INSTITUTE OF NEUROLOGY AND NEUROSURGERY   (Mexico)

^b MIDWESTERN UNIVERSITY   (United States)

Author keywords

Antidepressant; Bupropion; Diethylpropion; Dopamine release; GABA release; Glutamate release; Locomotor activity; Microdialysis

Indexed keywords

4 AMINOBUTYRIC ACID; AMFEBUTAMONE; AMFEPRAMONE; DOPAMINE; GLUTAMIC ACID;

4 AMINOBUTYRIC ACID RELEASE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINE BRAIN LEVEL; DOPAMINE RELEASE; LOCOMOTION; MALE; MICRODIALYSIS; NEUROCHEMISTRY; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RAT; WEIGHT REDUCTION;

ANALYSIS OF VARIANCE; ANIMALS; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; APPETITE DEPRESSANTS; BEHAVIOR, ANIMAL; BUPROPION; DIETHYLPROPION; DOPAMINE; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; MALE; MICRODIALYSIS; NEOSTRIATUM; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; RATS; RATS, WISTAR; SYNAPTIC TRANSMISSION;

EID: 77952319621     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2010.03.023     Document Type: Article

References (32)

1. Arias H.R. Is the inhibition of nicotinic acetylcholine receptors by bupropion involved in its clinical actions?. Int J Biochem Cell Biol 2009, 41:2098-2108.
2. Arias H.R., Santamaría A., Ali S. Pharmacological and neurotoxicological actions mediated by bupropion and diethylpropion. Int Rev Neurobiol 2009, 88:223-255. [special issue: new concepts of psychostimulants induced neurotoxicity].
3. Balcioglu A., Wurtman R.J. Effects of phentermine on striatal dopamine and serotonin release in conscious rats: in vivo microdialysis study. Int J Obes Relat Metab Disord 1998, 22:325-328.
4. Balleine B.W., Delgado M.R., Hikosaka O. The role of the dorsal striatum in reward and decision-making. J Neurosci 2007, 27:8161-8165.
5. Bruet N., Windels F., Carcenac C., Feuerstein C., Bertrand A., Poupard A., et al. Neurochemical mechanisms induced by high frequency stimulation of the subthalamic nucleus: Increase of extracellular striatal glutamate and GABA in normal and hemiparkinsonian rats. J Neuropathol Exp Neurol 2003, 62:1228-1240.
6. Coulter C.L., Happe H.K., Murrin L.C. Postnatal development of the dopamine transporter: a quantitative autoradiographic study. Brain Res Dev Brain Res 1996, 92:172-181.
7. Expósito I., Del Arco A., Segovia G., Mora F. Endogenous dopamine increases extracellular concentrations of glutamate and GABA in striatum of the freely moving rat: involvement of D1 and D2 dopamine receptors. Neurochem Res 1999, 24:849-856.
8. Galván-Arzate S., Santamaría A. Neurotoxicity of diethylpropion: neurochemical and behavioral findings in rats. Ann N Y Acad Sci 2002, 965:214-224.
9. García E., Limón D., Pérez-De La Cruz V., Giordano M., Díaz-Muñoz M., Maldonado P.D., et al. Lipid peroxidation, mitochondrial dysfunction and neurochemical and behavioural deficits in different neurotoxic models: protective role of S-allylcysteine. Free Radic Res 2008, 42:892-902.
10. Garcia-Mijares M., Bernardes A.M., Silva M.T. Diethylpropion produces psychostimulant and reward effects. Pharmacol Biochem Behav 2009, 91:621-628.
11. Gevaerd M.S., Sultowski E.T., Takahashi R.N. Combined effects of diethylpropion and alcohol on locomotor activity of mice: participation of the dopaminergic and opioid systems. Braz J Med Biol Res 1999, 32:1545-1550.
12. Holson R.R., Gazzara R.A., Gough B. Declines in stimulated striatal dopamine release over the first 32h following microdialysis probe insertion: generalization across releasing mechanisms. Brain Res 1998, 808:182-189.
13. Kimchi E.Y., Torregrossa M.M., Taylor J.R., Laubach M. Neuronal correlates of instrumental learning in the dorsal striatum. J Neurophysiol 2009, 102:475-489.
14. Mello E.L., Maior R.S., Carey R.J., Huston J.P., Tomaz C., Müller C.P. Serotonin1A-receptor antagonism blocks psychostimulant properties of diethylpropion in marmosets (Callithrix penicillata). Eur J Pharmacol 2005, 511:43-52.
15. Nomikos G.G., Damsma G., Wenkstern D., Fibiger H.C. Acute effects of bupropion on extracellular dopamine concentrations in rat striatum and nucleus accumbens studied by in vivo microdyalisis. Neuropsychopharmacology 1989, 2:273-279.
16. Paxinos G., Watson C. The rat brain in stereotaxic coordinates 1998, Academic Press Inc., San Diego, CA, USA.
17. Pérez-De La Cruz V., Elinos-Calderón D., Robledo-Arratia Y., Medina-Campos O.N., Pedraza-Chaverrí J., Ali S.F., et al. Targeting oxidative/nitrergic stress ameliorates motor impairment, and attenuates synaptic mitochondrial dysfunction and lipid peroxidation in two models of Huntington's disease. Behav Brain Res 2009, 199:210-217.
18. Planeta C.S., De Lucia R. Involvement of dopamine receptors in diethylpropion-induced conditioning place preference. Braz J Med Biol Res 1998, 31:561-564.
19. Reimer A.R., Martin-Iverson M.T., Urichuk L.J., Coutts R.T., Byrne A. Conditioned place preferences, conditioned locomotion, and behavioral sensitization occur in rats treated with diethylpropion. Pharmacol Biochem Behav 1995, 51:89-96.
20. Reid M.S., Herrera-Marschitz M., Hökfelt T., Lindefors N., Persson H., Ungerstedt U. Striatonigral GABA, dynorphin, substance P and neurokinin A modulation of nigrostriatal dopamine release: evidence for direct regulatory mechanisms. Exp Brain Res 1990, 82:293-303.
21. Samanin R., Garattini S. Neurochemical mechanism of action of anorectic drugs. Pharmacol Toxicol 1993, 73:63-68.
22. Santamaría A., Jiménez-Capdeville M.E., Camacho A., Rodríguez-Martínez E., Flores A., Galván-Arzate S. In vivo hydroxyl radical formation alter quinolinic acid infusion into the rat corpus striatum. Neuroreport 2001, 12:2693-2696.
23. Sidhpura N., Redfern P., Rowley H., Heal D., Wonnacott S. Comparison of the effects of bupropion and nicotine on locomotor activation and dopamine release in vivo. Biochem Pharmacol 2007, 74:1292-1298.
24. Silva-Adaya D., Pérez-De La Cruz V., Herrera-Mundo M.N., Mendoza-Macedo K., Villeda-Hernández J., Binienda Z., et al. Excitotoxic damage, disrupted energy metabolism, and oxidative stress in the rat brain: antioxidant and neuroprotective effects of l-carnitine. J Neurochem 2008, 105:677-689.
25. Silverstone T. Appetite suppressants: a review. Drugs 1992, 43:820-836.
26. Smith R.J., Panico K.A. Automated analysis of o-phtalaldehyde derivatives of amino acids in physiological fluids by reverse phase high performance liquid chromatography. J Liquid Chromatogr 1985, 8:1783-1795.
27. Surmeier D.J., Ding J., Day M., Wang Z., Shen W. D1 and D2 dopamine-receptor modulation of striatal glutamatergic signaling in striatal medium spiny neurons. Trends Neurosci 2007, 30:228-235.
28. Tella S.R., Ladenheim B., Cadet J.L. Differential regulation of dopamine transporter after chronic self-administration of bupropion and nomifensine. J Pharmacol Exp Ther 1997, 281:508-513.
29. Zhang L., Doyon W.M., Clarck J.J., Phillips P.E.M., Dani J.A. Controls of tonic and phasic dopamine transmission in the dorsal and ventral striatum. Mol Pharmacol 2009, 76:396-404.
30. Zhang T., Zhang L., Liang Y., Siapas A.G., Zhou F.M., Dani J.A. Dopamine signaling differences in the nucleus accumbens and dorsal striatum exploited by nicotine. J Neurosci 2009, 29:4035-4043.
31. Zhou F.M., Liang Y., Dani J.A. Endogenous nicotinic cholinergic activity regulates dopamine release in the striatum. Nat Neurosci 2001, 4:1224-1229.
32. Yu H., Rothman R.B., Dersch C.M., Partilla J.S., Rice K.C. Uptake and release effects of diethylpropion and its metabolites with biogenic amine transporters. Bioorg Med Chem 2000, 8:2689-2692.