The effect of blood transfusion on brain oxygenation in children with severe traumatic brain injury

Pediatric Critical Care Medicine

Volumn 11, Issue 3, 2010, Pages 325-331

  Figaji, Anthony A ^a   Zwane, Eugene ^a   Kogels, M ^a   Fieggen, A Graham ^a   Argent, Andrew C ^a   Le Roux, Peter D ^b   Peter, Jonathan C ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Blood transfusion; Brain tissue oxygen tension; Children; Head injury; Traumatic brain injury

Indexed keywords

HEMOGLOBIN; OXYGEN;

ARTICLE; BLOOD PRESSURE; BLOOD TRANSFUSION; BRAIN BLOOD FLOW; BRAIN OXYGEN TENSION; BRAIN PERFUSION; BRAIN TISSUE; CHILD; CONTROLLED STUDY; HEMODYNAMICS; HUMAN; MAJOR CLINICAL STUDY; OXYGEN TISSUE LEVEL; PATIENT MONITORING; PEDIATRIC HOSPITAL; PRIORITY JOURNAL; RETROSPECTIVE STUDY; TRAUMATIC BRAIN INJURY; TREATMENT RESPONSE; WHITE MATTER;

EID: 77952314331     PISSN: 15297535     EISSN: None     Source Type: Journal    
DOI: 10.1097/PCC.0b013e3181b80a8e     Document Type: Article

References (30)

1. Vincent JL, Piagnerelli M: Transfusion in the intensive care unit. Crit Care Med 2006;34:S96-S101
2. Armano R, Gauvin F, Ducruet T, et al: Determinants of red blood cell transfusions in a pediatric critical care unit: a prospective, descriptive epidemiological study. Crit Care Med 2005;33:2637-2644
3. Marik PE, Corwin HL: Efficacy of red blood cell transfusion in the critically ill: A systematic review of the literature. Crit Care Med 2008;36:2667-2674
4. Hebert PC, Yetisir E, Martin C, et al: Is a low transfusion threshold safe in critically ill patients with cardiovascular diseases? Crit Care Med 2001;29:227-234
5. Hare GM, Mazer CD, Hutchison JS, et al: Severe hemodilutional anemia increases cerebral tissue injury following acute neurotrauma. J Appl Physiol 2007;103:1021-1029
6. Hare GM, Tsui AK, McLaren AT, et al: Anemia and cerebral outcomes: many questions, fewer answers. Anesth Analg 2008;107:1356-1370
7. Sena MJ, Rivers RM, Muizelaar JP, et al: Transfusion practices for acute traumatic brain injury: a survey of physicians at US trauma centers. Intensive Care Med 2008;35:480-488
8. Salim A, Hadjizacharia P, DuBose J, et al: Role of anemia in traumatic brain injury. J Am Coll Surg 2008;207:398-406
9. Smith MJ, Stiefel MF, Magge S, et al: Packed red blood cell transfusion increases local cerebral oxygenation. Crit Care Med 2005;33:1104-1108
10. Figaji AA, Fieggen AG, Argent AC, et al: Does adherence to treatment targets in children with severe traumatic brain injury avoid brain hypoxia? A brain tissue oxygenation study. Neurosurgery 2008;63:83, 91 discussion 91-92
11. Yager JY, Thornhill JA: The effect of age on susceptibility to hypoxic-ischemic brain damage. Neurosci Biobehav Rev 1997;21:167-174
12. Desmet L, Lacroix J: Transfusion in pediatrics. Crit Care Clin 2004;20:299-311
13. Adelson PD, Bratton SL, Carney NA, et al: Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 1: Introduction. Pediatr Crit Care Med 2003;4:S2-S4
14. Adelson PD, Bratton SL, Carney NA, et al: Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 12. Use of hyperventilation in the acute management of severe pediatric traumatic brain injury. Pediatr Crit Care Med 2003;4:S45-S48
15. Leal-Noval SR, Rincon-Ferrari MD, Marin-Niebla A et al: Transfusion of erythrocyte concentrates produces a variable increment on cerebral oxygenation in patients with severe traumatic brain injury: a preliminary study. Intensive Care Med 2006;32:1733-1740
16. Leal-Noval SR, Munoz-Gomez M, Arellano-Orden V, et al: Impact of age of transfused blood on cerebral oxygenation in male patients with severe traumatic brain injury. Crit Care Med 2008;36:1290-1296
17. Zygun DA, Nortje J, Hutchinson PJ, et al: The effect of red blood cell transfusion on cerebral oxygenation and metabolism after severe traumatic brain injury. Crit Care Med 2009;37:1074-1078
18. Netzer G, Dutton RP, Hess JR: Right data, wrong conclusions. Crit Care Med 2008;36:1383-1384
19. Fitzgerald RD, Martin CM, Dietz GE, et al: Transfusing red blood cells stored in citrate phosphate dextrose adenine-1 for 28 days fails to improve tissue oxygenation in rats. Crit Care Med 1997;25:726-732
20. Raat NJ, Ince C: Oxygenating the microcirculation: the perspective from blood transfusion and blood storage. Vox Sang 2007;93:12-18
21. Walsh TS, McArdle F, McLellan SA, et al: Does the storage time of transfused red blood cells influence regional or global indexes of tissue oxygenation in anemic critically ill patients? Crit Care Med 2004;32:364-371
22. Hlatky R, Valadka AB, Gopinath SP, et al: Brain tissue oxygen tension response to induced hyperoxia reduced in hypoperfused brain. J Neurosurg 2008;108:53-58
23. Stiefel MF, Spiotta A Gracias VH, et al: Reduced mortality rate in patients with severe traumatic brain injury treated with brain tissue oxygen monitoring. J Neurosurg 2005;103:805-811
24. Enriquez P, Bullock R: Molecular and cellular mechanisms in the pathophysiology of severe head injury. Curr Pharm Des 2004;10:2131-2143
25. Astrup J, Sorensen PM, Sorensen HR: Oxygen and glucose consumption related to Na+-K+ transport in canine brain. Stroke 1981;12:726-730
26. Siesjo BK, Siesjo P: Mechanisms of secondary brain injury. Eur J Anaesthesiol 1996;13:247-268
27. Menon DK, Coles JP, Gupta AK, et al: Diffusion limited oxygen delivery following head injury. Crit Care Med 2004;32:1384-1390
28. Vespa PM, O'Phelan K, McArthur D, et al: Pericontusional brain tissue exhibits persistent elevation of lactate/pyruvate ratio independent of cerebral perfusion pressure. Crit Care Med 2007;35:1153-1160
29. Rosenthal G, Hemphill JC 3rd, Sorani M, et al: Brain tissue oxygen tension is more indicative of oxygen diffusion than oxygen delivery and metabolism in patients with traumatic brain injury. Crit Care Med 2008;36:1917-1924
30. Scheufler KM, Lehnert A, Rohrborn HJ, et al: Individual value of brain tissue oxygen pressure, microvascular oxygen saturation, cytochrome redox level, and energy metabolites in detecting critically reduced cerebral energy state during acute changes in global cerebral perfusion. J Neurosurg Anesthesiol 2004;16:210-219