Drug-resistant severe acanthamoeba keratitis caused by rare T5 acanthamoeba genotype

Eye and Contact Lens

Volumn 36, Issue 3, 2010, Pages 183-184

  Iovieno, Alfonso ^a   Oechsler, Rafael A ^a   Ledee, Dolena R ^a   Miller, Darlene ^a   Alfonso, Eduardo C ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORHEXIDINE; DORZOLAMIDE; POLY(HEXAMETHYLENEBIGUANIDE); PROPAMIDINE; PROTOZOAL DNA; TIMOLOL;

ACANTHAMOEBA; ACANTHAMOEBA KERATITIS; ACANTHAMOEBA LENTICULATA; ADULT; ANTIBIOTIC RESISTANCE; ARTICLE; CASE REPORT; CONFOCAL MICROSCOPY; DISEASE SEVERITY; DNA SEQUENCE; DRUG TREATMENT FAILURE; ENUCLEATION; EYE TOXICITY; FEMALE; GENE AMPLIFICATION; GENOTYPE; HUMAN; HUMAN TISSUE; INTRAOCULAR HYPERTENSION; INTRAOCULAR HYPOTENSION; NONHUMAN; PATIENT REFERRAL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SOFT CONTACT LENS; TISSUE CULTURE;

ACANTHAMOEBA; ACANTHAMOEBA KERATITIS; AMEBICIDES; BENZAMIDINES; DRUG RESISTANCE; EYE ENUCLEATION; FEMALE; GENOTYPE; HUMANS; MICROSCOPY, CONFOCAL; MIDDLE AGED; SEVERITY OF ILLNESS INDEX;

EID: 77952308039     PISSN: 15422321     EISSN: None     Source Type: Journal    
DOI: 10.1097/ICL.0b013e3181da2350     Document Type: Article

References (8)

1. Chong EM, Dana MR. Acanthamoeba keratitis. Int Ophthalmol Clin 2007;47:33-46.
2. Ledee DR, Byers TJ. Length and sequence heterogeneity in the mitochondrial internal transcribed spacer of Acanthamoeba spp. J Eukaryot Microbiol 2009;56:257-262.
3. Booton GC, Joslin CE, Shoff M, et al. Genotypic identification of Acanthamoeba sp. isolates associated with an outbreak of acanthamoeba keratitis. Cornea 2009;28:673-676.
4. Ledee DR, Iovieno A, Miller D, et al. Molecular identification of t4 and t5 genotypes in isolates from acanthamoeba keratitis patients. J Clin Microbiol 2009;47:1458-1462.
5. Spanakos G, Tzanetou K, Miltsakakis D, et al. Genotyping of pathogenic Acanthamoebae isolated from clinical samples in Greece-report of a clinical isolate presenting T5 genotype. Parasitol Int 2006;55:147-149.
6. Walochnik J, Obwaller A, Aspock H. Immunological inter-strain crossreactivity correlated to 18S rDNA sequence types in Acanthamoeba spp. Int J Parasitol 2001;31:163-167.
7. Barete S, Combes A, de Jonckheere JF, et al. Fatal disseminated Acanthamoeba lenticulata infection in a heart transplant patient. Emerg Infect Dis 2007;13:736-738.
8. Rivera WL, Adao DE. 18S ribosomal DNA genotypes of Acanthamoeba species isolated from contact lens cases in the Philippines. Parasitol Res 2009;105:1119-1124.