Liver Transplantation for Hepatocellular Carcinoma in the Model for End-Stage Liver Disease Era

Journal of the American College of Surgeons

Volumn 210, Issue 5, 2010, Pages 727-734

  Levi, David M ^a   Tzakis, Andreas G ^a   Martin, Paul ^a   Nishida, Seigo ^a   Island, Eddie ^a   Moon, Jang ^a   Selvaggi, Gennaro ^a   Tekin, Akin ^a   Madrazo, Beatrice L ^a   Narayanan, Govindarajan ^a   Garcia, Monica T ^a   Feun, Lynn G ^a   Tryphonopoulos, Panagiotis ^a   Skartsis, Nikolaos ^a   Livingstone, Alan S ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA FETOPROTEIN;

ADULT; AGED; ARTICLE; CANCER INVASION; CANCER LOCALIZATION; CANCER RECURRENCE; CANCER SIZE; CANCER STAGING; CANCER SURVIVAL; CONTROLLED STUDY; DISEASE FREE SURVIVAL; FEMALE; FOLLOW UP; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; KIDNEY FAILURE; LIVER CELL CARCINOMA; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RADIOFREQUENCY ABLATION; RETROSPECTIVE STUDY; TUMOR DIFFERENTIATION; COHORT ANALYSIS; LIVER TUMOR; MIDDLE AGED; MORTALITY; PATHOLOGY; PATIENT SELECTION; SURVIVAL RATE; TREATMENT OUTCOME;

ADULT; AGED; CARCINOMA, HEPATOCELLULAR; COHORT STUDIES; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; LIVER NEOPLASMS; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; NEOPLASM STAGING; PATIENT SELECTION; RETROSPECTIVE STUDIES; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 77952305382     PISSN: 10727515     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jamcollsurg.2010.01.007     Document Type: Article

References (36)

1. Mazzaferro V., Chun Y.S., Poon R.T., et al. Liver transplantation for hepatocellular carcinoma. Ann Surg Oncol 15 (2008) 1001-1007
2. Mazzaferro V., Regalia E., Doci R., et al. Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. N Engl J Med 334 (1996) 693-639
3. Freeman R.B., Wiesner R.H., Edwards E., et al. Results of the first year of the new liver allocation plan. Liver Transpl 10 (2004) 7-15
4. Sharma P., Balan V., Hernandez J.L., et al. Liver transplantation for hepatocellular carcinoma: the MELD impact. Liver Transpl 10 (2004) 36-41
5. American Liver Tumor Study Group. A randomized prospective multi-institutional trial of orthotopic liver transplantation or partial hepatic resection with or without adjuvant chemotherapy for hepatocellular carcinoma. Investigators Booklet and Protocol (1998)
6. Starzl T.E., Iwatsuki S., Esquivel C.O., et al. Refinements in the surgical techniques of liver transplantation. Semin Liver Dis 5 (1985) 349-356
7. Nishida S., Nakamura N., Vaidya A., et al. Piggyback techniques in adult liver transplantation: an analysis of 1067 liver transplants at a single center. HPB (Oxford) 8 (2006) 182-188
8. Pararas N., Levi D., Selvaggi G., et al. Mass clamping of the hilum to facilitate difficult hepatectomy during liver transplantation. Ann Surg 250 (2009) 273-276
9. Tzakis A.G., Tryphonopoulos P., Kato T., et al. Preliminary experience with alemtuzumab (Campath-1H) and low-dose tacrolimus immunosuppression in adult liver transplantation. Transplantation 77 (2004) 1209-1214
10. El-Serag H.B., Davila J.A., Petersen N.J., et al. The continuing increase in the incidence of hepatocellular carcinoma in the United States: an update. Ann Intern Med 139 (2003) 817-823
11. Bugianesi E. Non-alcoholic steatohepatitis and cancer. Clin Liver Dis 11 (2007) 191-207
12. Iwatsuki S., Starzl T.E., Sheahan D.G., et al. Hepatic resection versus transplantation for hepatocellular carcinoma. Ann Surg 214 (1991) 221-229
13. Bismuth H., Chiche L., Adam R., et al. Liver resection versus transplantation for hepatocellular carcinoma in cirrhotic patients. Ann Surg 218 (1993) 145-151
14. Ringe B., Wittekind C., Bechstein W.O., et al. The role of liver transplantation in hepatobiliary malignancy: a retrospective analysis of 95 patients with particular regard to tumor stage and recurrence. Ann Surg 209 (1989) 88-98
15. Schwartz M.E., Sung M., Mor E., et al. A multidisciplinary approach to hepatocellular carcinoma in patients with cirrhosis. J Am Coll Surg 180 (1995) 596-603
16. McPeake J.R., O'Grady J.G., Zaman S., et al. Liver transplantation for primary hepatocellular carcinoma: tumor size and number determine outcome. J Hepatol 18 (1993) 226-234
17. Lake J.R. MELD - an imperfect, but thus far the best, solution to the problem of organ allocation. J Gastrointestin Liver Dis 15 (2008) 5-7
18. Yao F.Y., Bass N.M., Nikolai B., et al. A follow-up analysis of the pattern and predictors of dropout from the waiting list for liver transplantation in patients with hepatocellular carcinoma: implications for the current organ allocation policy. Liver Transpl 9 (2003) 684-692
19. Thuluvath P.J., Maheshwari A., Thuluvath N.P., et al. Survival after liver transplantation for hepatocellular carcinoma in the MELD and pre-MELD eras and the independent impact of the hepatitis C virus. Transplantation 15 (2009) 754-762
20. Yao F.Y., Ferrell L., Bass N.M., et al. Liver transplantation for hepatocellular carcinoma: expansion of tumor size limits does not adversely impact survival. Hepatology 33 (2001) 1394-1403
21. Duffy J.P., Vardanian A., Benjamin E., et al. Liver transplantation criteria for hepatocellular carcinoma should be expanded. Ann Surg 246 (2007) 502-511
22. Schwartz M., Roayaie S., and Uva P. Treatment of HCC in patients awaiting liver transplantation. Am J Transplant 7 (2007) 1875-1881
23. Lu D.S.K., Yu N.C., Raman S.S., et al. Percutaneous radiofrequency ablation of hepatocellular carcinoma as a bridge to liver transplantation. Hepatology 41 (2005) 1130-1137
24. Porrett P.M., Peterman H., Rosen H., et al. Lack of benefit of pre-transplant locoregional hepatic therapy for hepatocellular carcinoma in the current MELD era. Liver Transpl 12 (2006) 665-673
25. Lesurtel M., Mullhaupt B., Pestalozzi B.C., et al. Transarterial chemoembolization as a bridge to liver transplantation for hepatocellular carcinoma: an evidence based analysis. Am J Transplant 6 (2006) 2644-2650
26. Belghiti J., Carr B.I., Greig P.D., et al. Treatment before liver transplantation for HCC. Ann Surg Onc 15 (2008) 993-1000
27. Yao Y.F., Kerlan R.K., Hirose R., et al. Excellent outcome following down-staging of hepatocellular carcinoma prior to liver transplantation: an intention to treat analysis. Hepatology 48 (2008) 819-827
28. Volk M.L., Vijan S., and Marrero J.A. A novel model measuring the harm of transplanting hepatocellular carcinoma exceeding Milan criteria. Am J Transpl 8 (2008) 839-846
29. Farinati F., Marino D., De Giorgio M., et al. Diagnostic role of alpha-fetoprotein in hepatocellular carcinoma: both or neither?. Am J Gastroenterol 101 (2006) 524-532
30. Vivarelli M., Cuchetti A., La Barba G., et al. Liver transplantation for hepatocellular carcinoma under calcineurin inhibitors: reassessment of risk factors for tumor recurrence. Ann Surg 248 (2008) 857-862
31. Yao F.Y., Xiao L., Bass N.M., et al. Liver transplantation for hepatocellular carcinoma: validation of the UCSF-expanded criteria based on preoperative imaging. Am J Transpl 7 (2007) 2587-2596
32. Yang S.H., Suh K., Lee H.W., et al. A revised scoring system utilizing serum alphafetoprotein levels to expand candidates for living donor transplantation in hepatocellular carcinoma. Surgery 141 (2007) 598-609
33. 18F-FDG-uptake of hepatocellular carcinoma on PET predicts microvascular tumor invasion in liver transplant patients. Am J Transpl 9 (2009) 592-600
34. Lee J.W., Paeng J.C., Kang K.W., et al. Prediction of tumor recurrence by 18F-FDG PET in liver transplantation for hepatocellular carcinoma. J Nucl Med 50 (2009) 682-687
35. Iizuka N., Oka M., Yamada-Okabe H., et al. Oligonucleotide microarray for prediction of early intrahepatic recurrence of hepatocellular carcinoma after curative resection. Lancet 361 (2003) 923-929
36. Hoshida Y., Villanueva A., Kobayashi M., et al. Gene expression in fixed tissues and outcome in hepatocellular carcinoma. N Engl J Med 359 (2008) 1995-2004