Early use of high-dose insulin euglycaemic therapy for verapamil toxicity

Medical Journal of Australia

Volumn 191, Issue 6, 2009, Pages 350-352

  Nickson, Christopher P ^a   Little, Mark ^a,b  

^a SIR CHARLES GAIRDNER HOSPITAL   (Australia)

^b ROYAL PERTH HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED CARBON; ADRENALIN; GLUCONATE CALCIUM; INSULIN; NALOXONE; VERAPAMIL;

ADULT; ARTICLE; ATRIOVENTRICULAR JUNCTION ARRHYTHMIA; CASE REPORT; DISEASE SEVERITY; DRUG MEGADOSE; DRUG SAFETY; EARLY INTERVENTION; GLUCOSE BLOOD LEVEL; HEART RATE; HUMAN; HYPOTENSION; MALE; PATIENT MONITORING; RECOMMENDED DRUG DOSE; RECURRENT DISEASE; SELF POISONING; SYSTOLIC BLOOD PRESSURE;

EID: 77952294594     PISSN: 0025729X     EISSN: 13265377     Source Type: Journal    
DOI: 10.5694/j.1326-5377.2009.tb02822.x     Document Type: Article

References (15)

1. Levine MD, Boyer E. Hyperinsulinemia-euglycemia therapy: a useful tool in treating calcium channel blocker poisoning. Crit Care 2006; 10: 149. (Pubitemid 47086915)
2. Greene SL, Gawarammana I, Wood DM, et al. Relative safety of hyperinsulinaemia/ euglycaemia therapy in the management of calcium channel blocker overdose: a prospective observational study. Intensive Care Med 2007; 33: 2019-2024. (Pubitemid 47632262)
3. Megarbane B, Karyo S, Baud FJ. The role of insulin and glucose (hyperinsulinaemia/euglycaemia) therapy in acute calcium channel antagonist and beta-blocker poisoning. Toxicol Rev 2004; 23: 215-222. (Pubitemid 41018275)
4. Lheureux PE, Zahir S, Gris M, et al. Bench-to-bedside review: hyperinsulinaemia/euglycaemia therapy in the management of overdose of calcium-channel blockers. Crit Care 2006; 10: 212. (Pubitemid 47086871)
5. Salhanick SD, Shannon MW. Management of calcium channel antagonist overdose. Drug Saf 2003; 26: 65-79.
6. Yuan TH, Kerns WP 2nd, Tomaszewski CA, et al. Insulin-glucose as adjunctive therapy for severe calcium channel antagonist poisoning. J Toxicol Clin Toxicol 1999; 37: 463-474.
7. Bailey B. Glucagon in beta-blocker and calcium channel blocker overdoses: a systematic review. J Toxicol Clin Toxicol 2003; 41: 595-602. (Pubitemid 37102385)
8. Kerns W 2nd. Management of beta-adrenergic blocker and calcium channel antagonist toxicity. Emerg Med Clin North Am 2007; 25: 309-331; abstract viii.
9. Murray L, Daly F, Little M, Cadogan M. Toxicology handbook. Sydney: Elsevier Australia, 2007.
10. Baud FJ, Megarbane B, Deye N, Leprince P. Clinical review: aggressive management and extracorporeal support for drug-induced cardiotoxicity. Crit Care 2007; 11: 207.
11. Holger JS, Engebretsen KM, Fritzlar SJ, et al. Insulin versus vasopressin and epinephrine to treat beta-blocker toxicity. Clin Toxicol (Phila) 2007; 45: 396-401.
12. Kline JA, Leonova E, Raymond RM. Beneficial myocardial metabolic effects of insulin during verapamil toxicity in the anesthetized canine. Crit Care Med 1995; 23: 1251-1263.
13. Place R, Carlson A, Leiken J, et al. Hyperinsulin therapy in the treatment of verapamil overdose [abstract]. J Toxicol Clin Toxicol 2000; 38: 576-577.
14. Holger JS, Engebretsen KM, Marini JJ. High dose insulin in toxic cardiogenic shock. Clin Toxicol (Phila) 2009; 47: 303-307.
15. Boyer EW, Shannon M. Treatment of calcium-channel-blocker intoxication with insulin infusion. N Engl J Med 2001; 344: 1721-1722. (Pubitemid 32479976)