-
1
-
-
55749096587
-
Innate immune signalling at intestinal mucosal surfaces: A fine line between host protection and destruction
-
Cario, E. (2008) Innate immune signalling at intestinal mucosal surfaces: a fine line between host protection and destruction. Curr. Opin. Gastroenterol. 24, 725-732
-
(2008)
Curr. Opin. Gastroenterol.
, vol.24
, pp. 725-732
-
-
Cario, E.1
-
2
-
-
38749083844
-
The "polarizing-tolerizing" mechanism of intestinal epithelium: Its relevance to colonic homeostasis
-
Lee, J., Gonzales-Navajas, J. M., and Raz, E. (2008) The "polarizing-tolerizing" mechanism of intestinal epithelium: its relevance to colonic homeostasis. Semin. Immunopathol. 30, 3-9
-
(2008)
Semin. Immunopathol.
, vol.30
, pp. 3-9
-
-
Lee, J.1
Gonzales-Navajas, J.M.2
Raz, E.3
-
3
-
-
61949313980
-
Intestinal barrier dysfunction in inflammatory bowel diseases
-
McGuckin, M. A., Eri, R., Simms, L. A., Florin, T. H., and Radford-Smith, G. (2009) Intestinal barrier dysfunction in inflammatory bowel diseases. Inflamm. Bowel Dis. 15, 100-113
-
(2009)
Inflamm. Bowel Dis.
, vol.15
, pp. 100-113
-
-
McGuckin, M.A.1
Eri, R.2
Simms, L.A.3
Florin, T.H.4
Radford-Smith, G.5
-
4
-
-
54349095456
-
Intestinal microflora and immunoregulation
-
Boirivant, M., Amendola, A., and Butera, A. (2008) Intestinal microflora and immunoregulation. Mucosal. Immunol. 1(Suppl. 1), S47-S49
-
(2008)
Mucosal. Immunol.
, vol.1
, Issue.SUPPL. 1
-
-
Boirivant, M.1
Amendola, A.2
Butera, A.3
-
5
-
-
34249313567
-
Paneth cells, defensins, and the commensal microbiota: A hypothesis on intimate interplay at the intestinal mucosa
-
Salzman, N. H., Underwood, M. A., and Bevins, C. L. (2007) Paneth cells, defensins, and the commensal microbiota: a hypothesis on intimate interplay at the intestinal mucosa. Semin. Immunol. 19, 70-83
-
(2007)
Semin. Immunol.
, vol.19
, pp. 70-83
-
-
Salzman, N.H.1
Underwood, M.A.2
Bevins, C.L.3
-
6
-
-
20744443283
-
Innate defenses of the intestinal epithelial barrier
-
Muller, C. A., Autenrieth, I. B., and Peschel, A. (2005) Innate defenses of the intestinal epithelial barrier. Cell. Mol. Life Sci. 62, 1297-1307
-
(2005)
Cell. Mol. Life Sci.
, vol.62
, pp. 1297-1307
-
-
Muller, C.A.1
Autenrieth, I.B.2
Peschel, A.3
-
7
-
-
44349132270
-
Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut
-
Artis, D. (2008) Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut. Nat. Rev. Immunol. 8, 411-420
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 411-420
-
-
Artis, D.1
-
8
-
-
0036423239
-
Molecular mechanisms of immunomodulatory activity of glucocorticoids
-
Riccardi, C., Bruscoli, S., and Migliorati, G. (2002) Molecular mechanisms of immunomodulatory activity of glucocorticoids. Pharmacol. Res. 45, 361-368
-
(2002)
Pharmacol. Res.
, vol.45
, pp. 361-368
-
-
Riccardi, C.1
Bruscoli, S.2
Migliorati, G.3
-
9
-
-
30744460611
-
Glucocorticoids in T cell apoptosis and function
-
Herold, M. J., McPherson, K. G., and Reichardt, H. M. (2006) Glucocorticoids in T cell apoptosis and function. Cell. Mol. Life Sci. 63, 60-72
-
(2006)
Cell. Mol. Life Sci.
, vol.63
, pp. 60-72
-
-
Herold, M.J.1
McPherson, K.G.2
Reichardt, H.M.3
-
10
-
-
0037643416
-
Molecular mechanisms of glucocorticoid action and resistance
-
Schaaf, M. J., and Cidlowski, J. A. (2002) Molecular mechanisms of glucocorticoid action and resistance. J. Steroid Biochem. Mol. Biol. 83, 37-48
-
(2002)
J. Steroid Biochem. Mol. Biol.
, vol.83
, pp. 37-48
-
-
Schaaf, M.J.1
Cidlowski, J.A.2
-
11
-
-
0031459881
-
Glucocorticoid-mediated repression of nuclear factor-kappaB-dependent transcription involves direct interference with transactivation
-
De Bosscher, K., Schmitz, M. L., Vanden Berghe, W., Plaisance, S., Fiers, W., and Haegeman, G. (1997) Glucocorticoid-mediated repression of nuclear factor-kappaB-dependent transcription involves direct interference with transactivation. Proc. Natl. Acad. Sci. U. S. A. 94, 13504-13509
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 13504-13509
-
-
De Bosscher, K.1
Schmitz, M.L.2
Vanden Berghe, W.3
Plaisance, S.4
Fiers, W.5
Haegeman, G.6
-
12
-
-
0028305712
-
Novel mechanism of glucocorticoid-mediated gene repression: Nuclear factor-kappaB is target for glucocorticoid-mediated interleukin 8 gene repression
-
Mukaida, N., Morita, M., Ishikawa, Y., Rice, N., Okamoto, S., Kasahara, T., and Matsushima, K. (1994) Novel mechanism of glucocorticoid-mediated gene repression. Nuclear factor-kappa B is target for glucocorticoid-mediated interleukin 8 gene repression. J. Biol. Chem. 269, 13289-13295 (Pubitemid 24978616)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.18
, pp. 13289-13295
-
-
Mukaida, N.1
Morita, M.2
Ishikawa, Y.3
Rice, N.4
Okamoto, S.-I.5
Kasahara, T.6
Matsushima, K.7
-
13
-
-
0033759766
-
Stress hormones: Good and bad
-
Sapolsky, R. M. (2000) Stress hormones: good and bad. Neurobiol. Dis. 7, 540-542
-
(2000)
Neurobiol. Dis.
, vol.7
, pp. 540-542
-
-
Sapolsky, R.M.1
-
15
-
-
11844281004
-
Intestinal epithelial cells synthesize glucocorticoids and regulate T cell activation
-
Cima, I., Corazza, N., Dick, B., Fuhrer, A., Herren, S., Jakob, S., Ayuni, E., Mueller, C., and Brunner, T. (2004) Intestinal epithelial cells synthesize glucocorticoids and regulate T cell activation. J. Exp. Med. 200, 1635-1646
-
(2004)
J. Exp. Med.
, vol.200
, pp. 1635-1646
-
-
Cima, I.1
Corazza, N.2
Dick, B.3
Fuhrer, A.4
Herren, S.5
Jakob, S.6
Ayuni, E.7
Mueller, C.8
Brunner, T.9
-
16
-
-
33748454319
-
The nuclear receptor LRH-1 critically regulates extra-adrenal glucocorticoid synthesis in the intestine
-
Mueller, M., Cima, I., Noti, M., Fuhrer, A., Jakob, S., Dubuquoy, L., Schoonjans, K., and Brunner, T. (2006) The nuclear receptor LRH-1 critically regulates extra-adrenal glucocorticoid synthesis in the intestine. J. Exp. Med. 203, 2057-2062
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2057-2062
-
-
Mueller, M.1
Cima, I.2
Noti, M.3
Fuhrer, A.4
Jakob, S.5
Dubuquoy, L.6
Schoonjans, K.7
Brunner, T.8
-
17
-
-
0026581936
-
RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement
-
Shinkai, Y., Rathbun, G., Lam, K. P., Oltz, E. M., Stewart, V., Mendelsohn, M., Charron, J., Datta, M., Young, F., Stall, A. M., and Alt, F. W. (1992) RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement. Cell 68, 855-867
-
(1992)
Cell
, vol.68
, pp. 855-867
-
-
Shinkai, Y.1
Rathbun, G.2
Lam, K.P.3
Oltz, E.M.4
Stewart, V.5
Mendelsohn, M.6
Charron, J.7
Datta, M.8
Young, F.9
Stall, A.M.10
Alt, F.W.11
-
18
-
-
34548712279
-
LRH-1-mediated glucocorticoid synthesis in enterocytes protects against inflammatory bowel disease
-
Coste, A., Dubuquoy, L., Barnouin, R., Annicotte, J. S., Magnier, B., Notti, M., Corazza, N., Antal, M. C., Metzger, D., Desreumaux, P., Brunner, T., Auwerx, J., and Schoonjans, K. (2007) LRH-1-mediated glucocorticoid synthesis in enterocytes protects against inflammatory bowel disease. Proc. Natl. Acad. Sci. U. S. A. 104, 13098-13103
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 13098-13103
-
-
Coste, A.1
Dubuquoy, L.2
Barnouin, R.3
Annicotte, J.S.4
Magnier, B.5
Notti, M.6
Corazza, N.7
Antal, M.C.8
Metzger, D.9
Desreumaux, P.10
Brunner, T.11
Auwerx, J.12
Schoonjans, K.13
-
19
-
-
0031688717
-
Analysis of liver regeneration in mice lacking type 1 or type 2 tumor necrosis factor receptor: Requirement for type 1 but not type 2 receptor
-
DOI 10.1002/hep.510280410
-
Yamada, Y., Webber, E. M., Kirillova, I., Peschon, J. J., and Fausto, N. (1998) Analysis of liver regeneration in mice lacking type 1 or type 2 tumor necrosis factor receptor: requirement for type 1 but not type 2 receptor. Hepatology 28, 959-970 (Pubitemid 28450256)
-
(1998)
Hepatology
, vol.28
, Issue.4 I
, pp. 959-970
-
-
Yamada, Y.1
Webber, E.M.2
Kirillova, I.3
Peschon, J.J.4
Fausto, N.5
-
20
-
-
0025000094
-
A new method for removal of mononuclear phagocytes from heterogeneous cell populations in vitro, using the liposome-mediated macrophage 'suicide' technique
-
Claassen, I., Van Rooijen, N., and Claassen, E. (1990) A new method for removal of mononuclear phagocytes from heterogeneous cell populations in vitro, using the liposome-mediated macrophage 'suicide' technique. J. Immunol. Methods 134, 153-161
-
(1990)
J. Immunol. Methods
, vol.134
, pp. 153-161
-
-
Claassen, I.1
Van Rooijen, N.2
Claassen, E.3
-
21
-
-
0026536293
-
Liposome-mediated elimination of macrophages
-
Van Rooijen, N. (1992) Liposome-mediated elimination of macrophages. Res. Immunol. 143, 215-219
-
(1992)
Res. Immunol.
, vol.143
, pp. 215-219
-
-
Van Rooijen, N.1
-
22
-
-
0027196986
-
Mechanisms of endotoxin shock and endotoxin hypersensitivity
-
Galanos, C., and Freudenberg, M. A. (1993) Mechanisms of endotoxin shock and endotoxin hypersensitivity. Immunobiology 187, 346-356
-
(1993)
Immunobiology
, vol.187
, pp. 346-356
-
-
Galanos, C.1
Freudenberg, M.A.2
-
23
-
-
62849093368
-
Death receptor signal transducers: Nodes of coordination in immune signaling networks
-
Wilson, N. S., Dixit, V., and Ashkenazi, A. (2009) Death receptor signal transducers: nodes of coordination in immune signaling networks. Nat. Immunol. 10, 348-355
-
(2009)
Nat. Immunol.
, vol.10
, pp. 348-355
-
-
Wilson, N.S.1
Dixit, V.2
Ashkenazi, A.3
-
24
-
-
0037204948
-
TNF-R1 signaling: A beautiful pathway
-
Chen, G., and Goeddel, D. V. (2002) TNF-R1 signaling: a beautiful pathway. Science 296, 1634-1635
-
(2002)
Science
, vol.296
, pp. 1634-1635
-
-
Chen, G.1
Goeddel, D.V.2
-
25
-
-
63049123701
-
Dax-1 and steroid receptor RNA activator (SRA) function as transcriptional coactivators for steroidogenic factor 1 in steroidogenesis
-
Xu, B., Yang, W. H., Gerin, I., Hu, C. D., Hammer, G. D., and Koenig, R. J. (2009) Dax-1 and steroid receptor RNA activator (SRA) function as transcriptional coactivators for steroidogenic factor 1 in steroidogenesis. Mol. Cell. Biol. 29, 1719-1734
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 1719-1734
-
-
Xu, B.1
Yang, W.H.2
Gerin, I.3
Hu, C.D.4
Hammer, G.D.5
Koenig, R.J.6
-
26
-
-
23844496151
-
Tumor necrosis factor-alpha induces apoptosis of enterocytes in mice with fulminant hepatic failure
-
Song, H. L., Lu, S., and Liu, P. (2005) Tumor necrosis factor-alpha induces apoptosis of enterocytes in mice with fulminant hepatic failure. World J. Gastroenterol. 11, 3701-3709 (Pubitemid 41149267)
-
(2005)
World Journal of Gastroenterology
, vol.11
, Issue.24
, pp. 3701-3709
-
-
Song, H.-L.1
Lu, S.2
Liu, P.3
-
27
-
-
0038153911
-
TNF-alpha neutralization ameliorates the severity of murine Crohn's-like ileitis by abrogation of intestinal epithelial cell apoptosis
-
Marini, M., Bamias, G., Rivera-Nieves, J., Moskaluk, C. A., Hoang, S. B., Ross, W. G., Pizarro, T. T., and Cominelli, F. (2003) TNF-alpha neutralization ameliorates the severity of murine Crohn's-like ileitis by abrogation of intestinal epithelial cell apoptosis. Proc. Natl. Acad. Sci. U. S. A. 100, 8366-8371
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 8366-8371
-
-
Marini, M.1
Bamias, G.2
Rivera-Nieves, J.3
Moskaluk, C.A.4
Hoang, S.B.5
Ross, W.G.6
Pizarro, T.T.7
Cominelli, F.8
-
28
-
-
0033818743
-
Leaks in the epithelial barrier caused by spontaneous and TNF-alpha-induced single-cell apoptosis
-
Gitter, A. H., Bendfeldt, K., Schulzke, J. D., and Fromm, M. (2000) Leaks in the epithelial barrier caused by spontaneous and TNF-alpha-induced single-cell apoptosis. FASEB J. 14, 1749-1753
-
(2000)
FASEB J.
, vol.14
, pp. 1749-1753
-
-
Gitter, A.H.1
Bendfeldt, K.2
Schulzke, J.D.3
Fromm, M.4
-
29
-
-
47349097005
-
Infliximab and etanercept are equally effective in reducing enterocyte APOPTOSIS in experimental colitis
-
Fries, W., Muja, C., Crisafulli, C., Costantino, G., Longo, G., Cuzzocrea, S., and Mazzon, E. (2008) Infliximab and etanercept are equally effective in reducing enterocyte APOPTOSIS in experimental colitis. Int. J. Med. Sci. 5, 169-180
-
(2008)
Int. J. Med. Sci.
, vol.5
, pp. 169-180
-
-
Fries, W.1
Muja, C.2
Crisafulli, C.3
Costantino, G.4
Longo, G.5
Cuzzocrea, S.6
Mazzon, E.7
-
30
-
-
62949219864
-
Biological therapies for inflammatory bowel diseases
-
Rutgeerts, P., Vermeire, S., and Van Assche, G. (2009) Biological therapies for inflammatory bowel diseases. Gastroenterology 136, 1182-1197
-
(2009)
Gastroenterology
, vol.136
, pp. 1182-1197
-
-
Rutgeerts, P.1
Vermeire, S.2
Van Assche, G.3
-
31
-
-
0035910751
-
Uncoupling the proinflammatory from the immunosuppressive properties of tumor necrosis factor (TNF) at the p55 TNF receptor level: Implications for pathogenesis and therapy of autoimmune demyelination
-
Kassiotis, G., and Kollias, G. (2001) Uncoupling the proinflammatory from the immunosuppressive properties of tumor necrosis factor (TNF) at the p55 TNF receptor level: implications for pathogenesis and therapy of autoimmune demyelination. J. Exp. Med. 193, 427-434
-
(2001)
J. Exp. Med.
, vol.193
, pp. 427-434
-
-
Kassiotis, G.1
Kollias, G.2
-
32
-
-
0023874728
-
Tumour necrosis factor-alpha in murine autoimmune 'lupus' nephritis
-
Jacob, C. O., and McDevitt, H. O. (1988) Tumour necrosis factor-alpha in murine autoimmune 'lupus' nephritis. Nature 331, 356-358
-
(1988)
Nature
, vol.331
, pp. 356-358
-
-
Jacob, C.O.1
McDevitt, H.O.2
-
33
-
-
0033947471
-
Accelerated autoimmunity and lupus nephritis in NZB mice with an engineered heterozygous deficiency in tumor necrosis factor
-
Kontoyiannis, D., and Kollias, G. (2000) Accelerated autoimmunity and lupus nephritis in NZB mice with an engineered heterozygous deficiency in tumor necrosis factor. Eur. J. Immunol. 30, 2038-2047
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 2038-2047
-
-
Kontoyiannis, D.1
Kollias, G.2
-
34
-
-
33847014113
-
Mechanism of glucocorticoid regulation of the intestinal tight junction barrier
-
Boivin, M. A., Ye, D., Kennedy, J. C., Al-Sadi, R., Shepela, C., and Ma, T. Y. (2007) Mechanism of glucocorticoid regulation of the intestinal tight junction barrier. Am. J. Physiol. Gastrointest. Liver Physiol. 292, G590-G598
-
(2007)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.292
-
-
Boivin, M.A.1
Ye, D.2
Kennedy, J.C.3
Al-Sadi, R.4
Shepela, C.5
Ma, T.Y.6
-
35
-
-
0033571441
-
Nonlymphocyte-derived tumor necrosis factor is required for induction of colitis in recombination activating gene (RAG)2(-/-) mice upon transfer of CD4(+)CD45RB(hi) T cells
-
Corazza, N., Eichenberger, S., Eugster, H. P., and Mueller, C. (1999) Nonlymphocyte-derived tumor necrosis factor is required for induction of colitis in recombination activating gene (RAG)2(-/-) mice upon transfer of CD4(+)CD45RB(hi) T cells. J. Exp. Med. 190, 1479-1492
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1479-1492
-
-
Corazza, N.1
Eichenberger, S.2
Eugster, H.P.3
Mueller, C.4
-
36
-
-
0034670047
-
Gene expressions of Toll-like receptor 2, but not Toll-like receptor 4, is induced by LPS and inflammatory cytokines in mouse macrophages
-
Matsuguchi, T., Musikacharoen, T., Ogawa, T., and Yoshikai, Y. (2000) Gene expressions of Toll-like receptor 2, but not Toll-like receptor 4, is induced by LPS and inflammatory cytokines in mouse macrophages. J. Immunol. 165, 5767-5772
-
(2000)
J. Immunol.
, vol.165
, pp. 5767-5772
-
-
Matsuguchi, T.1
Musikacharoen, T.2
Ogawa, T.3
Yoshikai, Y.4
-
37
-
-
0035424901
-
Decreased expression of Toll-like receptor-4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to bacterial lipopolysaccharide
-
Abreu, M. T., Vora, P., Faure, E., Thomas, L. S., Arnold, E. T., and Arditi, M. (2001) Decreased expression of Toll-like receptor-4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to bacterial lipopolysaccharide. J. Immunol. 167, 1609-1616 (Pubitemid 32703162)
-
(2001)
Journal of Immunology
, vol.167
, Issue.3
, pp. 1609-1616
-
-
Abreu, M.T.1
Vora, P.2
Faure, E.3
Thomas, L.S.4
Arnold, E.T.5
Arditi, M.6
-
38
-
-
0034650930
-
Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing toll-like receptors
-
Cario, E., Rosenberg, I. M., Brandwein, S. L., Beck, P. L., Reinecker, H. C., and Podolsky, D. K. (2000) Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing Toll-like receptors. J. Immunol. 164, 966-972 (Pubitemid 30043724)
-
(2000)
Journal of Immunology
, vol.164
, Issue.2
, pp. 966-972
-
-
Cario, E.1
Rosenberg, I.M.2
Brandwein, S.L.3
Beck, P.L.4
Reinecker, H.-C.5
Podolsky, D.K.6
-
39
-
-
1842583729
-
Mechanisms of cross hyporesponsiveness to Toll-like receptor bacterial ligands in intestinal epithelial cells
-
Otte, J. M., Cario, E., and Podolsky, D. K. (2004) Mechanisms of cross hyporesponsiveness to Toll-like receptor bacterial ligands in intestinal epithelial cells. Gastroenterology 126, 1054-1070
-
(2004)
Gastroenterology
, vol.126
, pp. 1054-1070
-
-
Otte, J.M.1
Cario, E.2
Podolsky, D.K.3
-
40
-
-
0037446528
-
Strategic compartmentalization of Toll-like receptor 4 in the mouse gut
-
Ortega-Cava, C. F., Ishihara, S., Rumi, M. A., Kawashima, K., Ishimura, N., Kazumori, H., Udagawa, J., Kadowaki, Y., and Kinoshita, Y. (2003) Strategic compartmentalization of Toll-like receptor 4 in the mouse gut. J. Immunol. 170, 3977-3985
-
(2003)
J. Immunol.
, vol.170
, pp. 3977-3985
-
-
Ortega-Cava, C.F.1
Ishihara, S.2
Rumi, M.A.3
Kawashima, K.4
Ishimura, N.5
Kazumori, H.6
Udagawa, J.7
Kadowaki, Y.8
Kinoshita, Y.9
-
41
-
-
34249337149
-
Adaptations of intestinal macrophages to an antigen-rich environment
-
Schenk, M., and Mueller, C. (2007) Adaptations of intestinal macrophages to an antigen-rich environment. Semin. Immunol. 19, 84-93
-
(2007)
Semin. Immunol.
, vol.19
, pp. 84-93
-
-
Schenk, M.1
Mueller, C.2
-
42
-
-
0141814990
-
Tumor necrosis factor alpha-dependent up-regulation of Lrh-1 and Mrp3(Abcc3) reduces liver injury in obstructive cholestasis
-
Bohan, A., Chen, W. S., Denson, L. A., Held, M. A., and Boyer, J. L. (2003) Tumor necrosis factor alpha-dependent up-regulation of Lrh-1 and Mrp3(Abcc3) reduces liver injury in obstructive cholestasis. J. Biol. Chem. 278, 36688-36698
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 36688-36698
-
-
Bohan, A.1
Chen, W.S.2
Denson, L.A.3
Held, M.A.4
Boyer, J.L.5
|