Chronic high Epstein-Barr viral load carriage in pediatric small bowel transplant recipients

Pediatric Transplantation

Volumn 14, Issue 4, 2010, Pages 549-553

  Lau, Audrey H ^a   Soltys, Kyle ^b   Sindhi, Rakesh K ^b   Bond, Geoffrey ^b   Mazariegos, George V ^b   Green, Michael ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

Author keywords

Epstein Barr virus; Intestinal transplantation; Post transplant lymphoproliferative disorder

Indexed keywords

ARTICLE; CHILD; CONTROLLED STUDY; DISEASE CARRIER; DISEASE SURVEILLANCE; ENTERITIS; EPSTEIN BARR VIRUS; EPSTEIN BARR VIRUS INFECTION; GRAFT RECIPIENT; HUMAN; INTESTINE TRANSPLANTATION; MAJOR CLINICAL STUDY; OUTCOME ASSESSMENT; POPULATION RESEARCH; RETROSPECTIVE STUDY; SEROPREVALENCE; SPINDLE CELL CARCINOMA; VIRUS LOAD; CHRONIC DISEASE; EPSTEIN-BARR VIRUS INFECTIONS; FEMALE; HEALTH SURVEY; HETEROZYGOTE; ISOLATION AND PURIFICATION; LIVER TRANSPLANTATION; MALE; PROSPECTIVE STUDY; SMALL INTESTINE; TRANSPLANTATION; UNITED STATES; VIROLOGY;

CARRIER STATE; CHILD; CHRONIC DISEASE; EPSTEIN-BARR VIRUS INFECTIONS; FEMALE; HERPESVIRUS 4, HUMAN; HUMANS; INTESTINE, SMALL; LIVER TRANSPLANTATION; MALE; PENNSYLVANIA; POPULATION SURVEILLANCE; PROSPECTIVE STUDIES; VIRAL LOAD;

EID: 77952274815     PISSN: 13973142     EISSN: 13993046     Source Type: Journal    
DOI: 10.1111/j.1399-3046.2009.01283.x     Document Type: Article

References (14)

1. Green M, Michaels MG, Katz BZ, et al. CMV-IVIG for prevention of Epstein-Barr virus disease and posttransplant lymphoproliferative disease in pediatric liver transplant recipients. Am J Transplant 2006 : 6 : 1906 1912.
2. Webber SA, Green M. Post-transplant lymphoproliferative disorders following pediatric heart transplantation. In : Fine R, Webber SA, Harmon W, Olthoff K, Kelly D, eds. Pediatric Solid Organ Transplantation, 2nd edn.
3. Webber SA, Naftel DC, Fricker FJ, et al. Lymphoproliferative disorders after paediatric heart transplantation: A multi-institutional study. Lancet 2006 : 367 : 233 239.
4. Green M, Reyes J, Webber S, Michaels MG, Rowe D. The role of viral load in the diagnosis, management, and possible prevention of Epstein-Barr virus-associated posttransplant lymphoproliferative disease following solid organ transplantation. Curr Opin Organ Transplant 1999 : 4 : 292 296.
5. Rowe DT, Qu L, Reyes J, et al. Use of quantitative competitive PCR to measure Epstein-Barr virus genome load in the peripheral blood of pediatric transplant patients with lymphoproliferative disorders. J Clin Microbiol 1997 : 35 : 1612 1615.
6. Rowe DT, Webber S, Schauer EM, Reyes J, Green M. Epstein-Barr virus load monitoring: Its role in the prevention and management of post-transplant lymphoproliferative disease. Transpl Infect Dis 2001 : 3 : 79 87.
7. Green M, Webber SA. EBV viral load monitoring: Unanswered questions. Am J Transplant 2002 : 2 : 894 895.
8. Bingler MA, Feingold B, Miller SA, et al. Chronic high Epstein-Barr viral load state and risk for late-onset posttransplant lymphoproliferative disease/lymphoma in children. Am J Transplant 2008 : 8 : 442 445.
9. Green M, Cacciarelli TV, Mazariegos GV, et al. Serial measurement of Epstein-Barr viral load in peripheral blood in pediatric liver transplant recipients during treatment for posttransplant lymphoproliferative disease. Transplantation 1998 : 66 : 1641 1644.
10. Green M, Soltys K, Rowe DT, Webber SA, Mazareigos G. Chronic high Epstein-Barr viral load carriage in pediatric liver transplant recipients. Pediatr Transplant 2009 : 13 : 319 323.
11. Green M, Webber SA. Persistent increased Epstein-Barr virus loads after solid organ transplantation: Truth and consequences? Liver Transpl 2007 : 13 : 321 322.
12. Qu L, Green M, Webber S, Reyes J, Ellis D, Rowe D. Epstein-Barr virus gene expression in the peripheral blood of transplant recipients with persistent circulating virus loads. J Infect Dis 2000 : 182 : 1013 1021.
13. Wadowsky RM, Laus S, Green M, Webber SA, Rowe D. Measurement of Epstein-Barr virus DNA loads in whole blood and plasma by TaqMan PCR and in peripheral blood lymphocytes by competitive PCR. J Clin Microbiol 2003 : 41 : 5245 5249.
14. Harris N, Swerdlow S, Frizzera G, Knowles D. Post-transplant lymphoproliferative disorders. In : Jaffe E, Harris N, Stein H, Vardiman J, eds. World Health Organization Classification of Tumors: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues.